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Chemical Structure| 1314968-29-0 Chemical Structure| 1314968-29-0

Structure of 1314968-29-0

Chemical Structure| 1314968-29-0

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Product Details of [ 1314968-29-0 ]

CAS No. :1314968-29-0
Formula : C6H9N3O
M.W : 139.16
SMILES Code : CNC1=CN=C(OC)N=C1
MDL No. :MFCD19226755

Safety of [ 1314968-29-0 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 1314968-29-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1314968-29-0 ]

[ 1314968-29-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 50-00-0 ]
  • [ 56621-89-7 ]
  • [ 1314968-29-0 ]
YieldReaction ConditionsOperation in experiment
31% With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20℃; for 18h;Molecular sieve; A solution of 2- methoxypyrimidin-5-amine (100 mg, 0.8 mmol) and activated molecular sieves 3A (60 mg) in DCE (2.0 mL) was treated with paraformaldehyde (144 mg, 4.8 mmol) and sodium triacetoxyborohydride (509 mg, 2.4 mmol). The resulting mixture was allowed to stir at room temperature for 18h, then filtered over a glass filter and the resulting crude mixture was washed few timeswith DCM. Removal of the solvent gave a crude product which was subjected to flash chromatography on neutral alumina gel Al2O3, pH = 7) eluting with DCM as solvent To give the compound as white solid in 31% yield: 1H NMR (400 MHz, DMSO-d6) delta 7.94 (s, 2H), 5.57 - 5.44 (m, 1H), 3.78 (s, 3H), 2.67 (d, J = 5.3 Hz, 3H).
 

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