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Chemical Structure| 132335-49-0 Chemical Structure| 132335-49-0

Structure of 132335-49-0

Chemical Structure| 132335-49-0

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Product Details of [ 132335-49-0 ]

CAS No. :132335-49-0
Formula : C9H15NOS
M.W : 185.29
SMILES Code : O[C@@H](C1=CC=CS1)CCN(C)C
MDL No. :MFCD11558915
InChI Key :XWCNSHMHUZCRLN-MRVPVSSYSA-N
Pubchem ID :10103884

Safety of [ 132335-49-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Application In Synthesis of [ 132335-49-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 132335-49-0 ]
  • Downstream synthetic route of [ 132335-49-0 ]

[ 132335-49-0 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 321-38-0 ]
  • [ 144-62-7 ]
  • [ 132335-49-0 ]
  • [ 132335-47-8 ]
YieldReaction ConditionsOperation in experiment
75.6%
Stage #1: With sodium hydride In N,N-dimethyl acetamide at 70℃; for 0.333333 h;
Stage #2: at 110℃; for 1 h;
DX-A 03 (2.0 g, 0.011 mol)Was dissolved in dimethylacetamide (100 mL)A solution of 60percent sodium hydride (463 mg, 0.012 mol)Dropwise.The resulting mixture was heated at 70 ° C. for 20 minutes.1-Fluoronaphthalene (1.27 mL, 0.012 mol)Was added dropwise to this mixed solution,And heated at 110 ° C. for 60 minutes.The reaction mixture was diluted with water,And extracted twice with diethyl ether.The extracts are combined,Wash with water,Then washed with saturated sodium chloride solution,It was dried over anhydrous sodium sulfate,After concentration under reduced pressure,To obtain an oily compound (DX-A 04, 3.28 g, 75.6percent).
References: [1] Patent: JP2016/172704, 2016, A, . Location in patent: Paragraph 0027; 0053.
 

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