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Chemical Structure| 1359869-36-5 Chemical Structure| 1359869-36-5

Structure of 1359869-36-5

Chemical Structure| 1359869-36-5

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Product Details of [ 1359869-36-5 ]

CAS No. :1359869-36-5
Formula : C9H10IN
M.W : 259.09
SMILES Code : NC1=CC=C(I)C2=C1CCC2
MDL No. :MFCD23162662

Safety of [ 1359869-36-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Application In Synthesis of [ 1359869-36-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1359869-36-5 ]

[ 1359869-36-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 32202-61-2 ]
  • [ 1359869-36-5 ]
YieldReaction ConditionsOperation in experiment
With Iodine monochloride; In acetic acid; at 20℃; Example 3, Step aTo a solution of <strong>[32202-61-2]4-aminoindan</strong> (5 g, 37.56 mmol) in acetic acid (350 mL) was added dropwise IC1 (6.09 g, 37.56 mmol) in acetic acid (14 mL) at room temperature. The resulting solution was stirred overnight. Upon completion of the reaction, the solvent was evaporated under reduced pressure. The residue was dissolved in EtOAc (200 mL) and the solution was washed with saturated aHC03 solution and the aqueous layer was extracted with EtOAc (200 mL). The combined extracts were washed with water, brine, dried over Na2S04 and concentrated in vacuo. The crude was purified by flash chromatography (ISCO, EtOAc: petroleum ether, 1 1 :89) to obtain iodide 3a (6.4 g) as a white solid. LC/MS (Condition 9): Rt = 1.40 min. lH NMR (CDC13, delta = 7.26 ppm, 400 MHz): delta 7.31 (d, J = 8.4, 1H), 6.29 (d, J = 8.4, 1H), 3.55 ( br s, 2H), 2.91-2.84 (m , 4H), 2.13-2.06 (m, 2H). LC/MS: Anal. Calcd. for [M+H]+ C9H11I : 259.99; found 260.0.
 

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