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Chemical Structure| 1361537-47-4 Chemical Structure| 1361537-47-4

Structure of 1361537-47-4

Chemical Structure| 1361537-47-4

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Product Details of [ 1361537-47-4 ]

CAS No. :1361537-47-4
Formula : C14H20IN3O4
M.W : 421.23
SMILES Code : IC(C=N1)=CN=C1N(C(OC(C)(C)C)=O)C(OC(C)(C)C)=O
MDL No. :MFCD28137693

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Application In Synthesis of [ 1361537-47-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1361537-47-4 ]

[ 1361537-47-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1445-39-2 ]
  • [ 24424-99-5 ]
  • [ 1361537-47-4 ]
YieldReaction ConditionsOperation in experiment
97% With dmap; In tetrahydrofuran; for 24h;Reflux; <strong>[1445-39-2]2-Amino-5-iodopyrimidine</strong> (1.0 g, 4.52 mmol, 1.0 eq.), di-tert-butyldicarbonate (2.39 g, 10.9 mmol,2.4 eq.) and 4-dimethylaminopyridine (0.14 g, 1.15 mmol, 0.26 eq.) were dissolved in THF (50 mL)and refluxed for 24 h. The solvent was removed under reduced pressure and the brown solid waspurified via column chromatography (hexane/ethyl acetate, 3:1, Rf = 0.60) to give N, N-di-tertbutoxycarbonyl-<strong>[1445-39-2]5-iodopyrimidin-2-amine</strong> 2b (1.85 g, 97%) as a colorless solid (m.p.: 147 C).
 

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