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Chemical Structure| 1369782-16-0 Chemical Structure| 1369782-16-0

Structure of 1369782-16-0

Chemical Structure| 1369782-16-0

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Product Details of [ 1369782-16-0 ]

CAS No. :1369782-16-0
Formula : C9H8BrN
M.W : 210.07
SMILES Code : N#CC1=CC(CC)=CC(Br)=C1
MDL No. :MFCD23163451

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Application In Synthesis of [ 1369782-16-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1369782-16-0 ]

[ 1369782-16-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 59785-43-2 ]
  • copper(l) cyanide [ No CAS ]
  • [ 1369782-16-0 ]
YieldReaction ConditionsOperation in experiment
With pyridine; In N,N-dimethyl-formamide; at 150℃; for 3h; Intermediate 583-Bromo-5-ethylbenzonitrile; A mixture of <strong>[59785-43-2]1,3-dibromo-5-ethylbenzene</strong> (2.7 g, 10.2 mmol), copper cyanide (0.916 g, 10.2 mmol), pyridine (1.65 mL, 20.5 mmol) in DMF (15 mL) was heated at 150 C. for 3 h. After cooling to r.t., the mixture was poured into a solution of H2O (30 mL) and ammonia (25% aq. Solution, 20 mL) and extracted with EtOAc. The combined organic layer was dried (MgSO4), filtered and concentrated in vacuo. The product was purified using flash chromatography on silica gel, gradient elution of 0-60% EtOAc in n-heptane. GCMS (CI) m/z 210 [M+1]+.
 

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