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Structure of Voriconazole
CAS No.: 137234-62-9
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Voriconazole is a second-generation triazole antifungal used to treat serious fungal infections by inhibiting the synthesis of ergosterol, the major sterol of the fungal cell membrane.
Synonyms: UK-109496; DRG 0301; Vfend
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 137234-62-9 |
Formula : | C16H14F3N5O |
M.W : | 349.31 |
SMILES Code : | O[C@@]([C@@H](C)C1=NC=NC=C1F)(CN2N=CN=C2)C(C(F)=C3)=CC=C3F |
Synonyms : |
UK-109496; DRG 0301; Vfend
|
MDL No. : | MFCD00905717 |
InChI Key : | BCEHBSKCWLPMDN-VQVVDHBBSA-N |
Pubchem ID : | 69155711 |
GHS Pictogram: |
![]() ![]() |
Signal Word: | Danger |
Hazard Statements: | H301-H360 |
Precautionary Statements: | P501-P270-P202-P201-P264-P280-P308+P313-P301+P310+P330-P405 |
Class: | 6.1 |
UN#: | 2811 |
Packing Group: | Ⅲ |
In Vitro:
Concentration | Treated Time | Description | References |
Candida albicans SC 5314 | 1.0 µg/mL | To evaluate the antifungal activity of Voriconazole and its salts against Candida albicans | PMC6832385 | |
Candida glabrata DSM 11226 | 4.0 µg/mL | To evaluate the antifungal activity of Voriconazole and its salts against Candida glabrata | PMC6832385 | |
Candida krusei DSM 6128 | 2.0 µg/mL | To evaluate the antifungal activity of Voriconazole and its salts against Candida krusei | PMC6832385 | |
Candida tropicalis KKP 334 | 0.25 µg/mL | To evaluate the antifungal activity of Voriconazole and its salts against Candida tropicalis | PMC6832385 | |
Candida lusitaniae DSM 70102 | 0.062 µg/mL | To evaluate the antifungal activity of Voriconazole and its salts against Candida lusitaniae | PMC6832385 | |
Rat liver microsomes | 0.01, 0.1, 1, 10, 25, 50, 100 µM | 50 minutes | Voriconazole inhibited the metabolism of vonoprazan with an IC50 of 2.93 μM, showing mixed inhibition. | PMC7280087 |
In Vivo:
Administration | Dosage | Frequency | Description | References |
Sprague-Dawley rats | Sprague-Dawley rats | Oral | 30 mg/kg | Single dose and multiple doses (14 days) | To investigate the effects of voriconazole on the pharmacokinetics of vonoprazan, results showed that voriconazole increased the area under the plasma concentration-time curve (AUC), prolonged the elimination half-life (t1/2), and decreased the clearance (CL) of vonoprazan. | PMC7280087 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT02381080 | B-Cell Chronic Lymphocytic Leu... More >>kemia Less << | Phase 1 | Completed | - | Canada ... More >> N/a N/a, Canada Russian Federation Moscow, Russian Federation Petrozavodsk, Russian Federation St. Petersburg, Russian Federation Spain Madrid, Spain Pamplona, Spain Less << |
NCT00003031 | Infection Pul... More >>monary Complications Less << | Phase 3 | Completed | - | - |
NCT01787032 | Healthy | Phase 1 | Completed | - | Germany ... More >> Boehringer Ingelheim Investigational Site Ingelheim, Germany Less << |
NCT00177788 | - | Completed | - | United States, Pennsylvania ... More >> University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 Less << | |
NCT00624143 | Pediatric Acute Leukemia Induc... More >>tion Less << | Phase 3 | Unknown | - | India ... More >> Institute Rotary Cancer Hospital, All India Institute of Medical Sciences Recruiting New Delhi, Delhi, India, 110029 Contact: SAMEER BAKHSHI, MD 91-11-26588153 sambakh@hotmail.com Less << |
NCT01787032 | - | Completed | - | - | |
NCT00001646 | Acquired Immunodeficiency Synd... More >>rome Aspergillosis HIV Infections Immunologic Deficiency Syndromes Neutropenia Less << | Phase 3 | Completed | - | United States, Maryland ... More >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Less << |
NCT03554239 | Infection | Not Applicable | Terminated | - | - |
NCT00079222 | Cancer | Not Applicable | Completed | - | United States, California ... More >> Jonsson Comprehensive Cancer Center, UCLA Los Angeles, California, United States, 90095-1678 Less << |
NCT01321372 | - | Completed | - | Canada, Ontario ... More >> Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Less << | |
NCT00059878 | Infection Uns... More >>pecified Adult Solid Tumor, Protocol Specific Less << | Phase 2 | Completed | - | United States, Arkansas ... More >> Arkansas Cancer Research Center at University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72205 United States, Florida Shands Cancer Center at the University of Florida Health Science Center Gainesville, Florida, United States, 32610-100277 United States, Maryland Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support Bethesda, Maryland, United States, 20892-1182 Less << |
NCT00740389 | HIV AIDS ... More >> Fungal Infection Less << | Phase 1 | Completed | - | - |
NCT00001757 | Mycoses | PHASE3 | COMPLETED | 2000-07-01 | National Institute of Allergy ... More >>and Infectious Diseases (NIAID), Bethesda, Maryland, 20892, United States Less << |
NCT00557362 | Fungal Keratitis | Phase 1 Phase 2 | Completed | - | India ... More >> Aravind Eye Hospital Madurai, Tamil Nadu, India Aravind Eye Hospital Pondicherry, Tamil Nadu, India Less << |
NCT00015665 | Mycoses | PHASE3 | COMPLETED | 2025-03-03 | National Institute of Allergy ... More >>and Infectious Diseases (NIAID), Bethesda, Maryland, 20892, United States Less << |
NCT00557362 | - | Completed | - | - | |
NCT00001810 | Aspergillosis|Candidiasis|Fung... More >>emia|Mycoses Less << | PHASE3 | COMPLETED | 2000-10-01 | National Cancer Institute (NCI... More >>), Bethesda, Maryland, 20892, United States Less << |
NCT00005912 | Aspergillosis|Candidiasis|Fung... More >>al Diseases|Mycoses Less << | PHASE1 | COMPLETED | 2025-01-01 | National Cancer Institute (NCI... More >>), Bethesda, Maryland, 20892, United States Less << |
NCT01344512 | Pediatrics Ce... More >>ftazidime Ciprofloxacin Voriconazole Less << | Not Applicable | Completed | - | France ... More >> CHU de Bordeaux, Hôpital Pellegrin Bordeaux, France, 33076 Hospices Civils de Lyon Bron, France, 69500 CHU Clermont Ferrand Clermont Ferrand, France, 63000 CHU de Dijon Dijon, France, 21079 CHU de Grenoble Grenoble, France, 38043 CHRU Lille Lille, France, 59037 AP-HM, Hôpital La Timone Marseille, France, 13005 CHU Montpellier Montpellier, France, 34925 APHP - Hôpital NEcker Paris, France, 75015 AP-HP - Hôpital Robert Debré Paris, France, 75019 CHU Poitiers Poitiers, France, 86000 CHU Rouen Rouen, France, 76031 CHU Toulouse Toulouse, France, 31059 CHU tours Tours, France, 37044 Less << |
NCT00288197 | Invasive Fungal Infections | Phase 4 | Completed | - | China, Guangdong ... More >> Pfizer Investigational Site Guangzhou, Guangdong, China, 510080 China, Hubei Pfizer Investigational Site Wuhan, Hubei, China, 430022 Pfizer Investigational Site Wuhan, Hubei, China, 430030 China Pfizer Investigational Site Beijing, China, 100083 Pfizer Investigational Site Beijing, China, 100853 Pfizer Investigational Site Hangzhou, China, 310003 Pfizer Investigational Site Shanghai, China, 200040 Pfizer Investigational Site Shanghai, China, 200080 Pfizer Investigational Site Tianjin, China, 300020 Pfizer Investigational Site Tianjin, China, 300052 Less << |
NCT00066599 | Kidney Cancer ... More >> Leukemia Lymphoma Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms Neuroblastoma Neutropenia Sarcoma Less << | Phase 2 | Completed | - | United States, California ... More >> Children's Hospital of Orange County Orange, California, United States, 92868 Children's Hospital and Health Center, San Diego San Diego, California, United States, 92123-4282 United States, Maryland Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support Bethesda, Maryland, United States, 20892-1182 United States, North Carolina Duke Comprehensive Cancer Center Durham, North Carolina, United States, 27710 United States, Ohio Ireland Cancer Center Cleveland, Ohio, United States, 44106-5065 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104-4318 United States, Texas Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas Dallas, Texas, United States, 75390 Less << |
NCT00412893 | Aspergillosis ... More >> Invasive Fungal Infection Less << | Phase 3 | Completed | - | - |
NCT02180165 | Aspergillosis | Phase 3 | Completed | - | - |
NCT01621321 | Allergic Bronchopulmonary Aspe... More >>rgillosis Less << | Phase 2 Phase 3 | Completed | - | India ... More >> Postgraduate Institute of Medical Education and Research Chandigarh, India, 160012 Less << |
NCT00001940 | Mycoses | PHASE3 | COMPLETED | 2025-07-01 | National Cancer Institute (NCI... More >>), Bethesda, Maryland, 20892, United States Less << |
NCT00418951 | Acute Myelogenous Leukemia ... More >> Myelodysplastic Syndrome Less << | Phase 2 | Completed | - | United States, Texas ... More >> The University of Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 Less << |
NCT00423163 | Aspergillosis/Blood ... More >> Aspergillosis/Invasive Less << | Phase 4 | Withdrawn(An alternative joint... More >> industry effort will provide information on combination versus single agent therapy for treatment of aspergillosis) Less << | - | - |
NCT00412893 | - | Completed | - | - | |
NCT00150319 | Kidney Failure | Phase 1 Phase 2 | Terminated(See Detailed Descri... More >>ption) Less << | - | United States, Louisiana ... More >> Pfizer Investigational Site New Orleans, Louisiana, United States, 70118 Pfizer Investigational Site New Orleans, Louisiana, United States, 70119 United States, Minnesota Pfizer Investigational Site Minneapolis, Minnesota, United States, 55404 United States, Tennessee Pfizer Investigational Site Knoxville, Tennessee, United States, 37920 United States, Texas Pfizer Investigational Site Austin, Texas, United States, 78727 Pfizer Investigational Site Austin, Texas, United States, 78758 Less << |
NCT00455364 | Infection | PHASE4 | TERMINATED | 2025-04-07 | The University of Chicago, Chi... More >>cago, Illinois, 60637, United States Less << |
NCT00418951 | - | Completed | - | - | |
NCT01576315 | Cystic Fibrosis ... More >> Aspergillus Infections Less << | Phase 2 | Completed | - | France ... More >> CRCM Adulte et Pédiatrie - Hôpital Nord Amiens, France, 80054 CRCM adulte - Centre Robert Debré Angers, France, 49033 Pediatry - Centre Robert Debré Angers, France, 49033 Pediatric penumologic - Groupe hospitalier de Pellegrin Bordeaux, France, 33000 Pneumology pediatric - Hôpital Femme-Mère-Enfants Bron, France, 69500 CRCM - Pediatry - CHI Créteil Créteil, France, 94000 Service de Pneumologie-Immuno-Allergologie / Hôpital Calmette Lille, France, 59037 Hôpital Nord - Pneumology Marseille, France, 13015 Pneumologie Infantile - Hôpital des enfants Nancy, France, 54577 CRCM - Hôpital Sud Rennes, France, 35000 Pneumology - Hôpital Pontchaillou Rennes, France, 35000 CRCM Pédiatrique - Hôpital de Hautepierre Strasbourg, France, 67098 Pédiatrie - Pneumologie, Allergologie - Hôpital des enfants Toulouse, France, 31059 Pneumology - CH Bretagne-Atlantique Vannes, France, 56017 United Kingdom Manchester Adult Cystic Fibrosis Centre - University Hospital of South Manchester Manchester, United Kingdom, M23 9LT Less << |
NCT00940017 | Aspergillosis ... More >> Candidemia Less << | Phase 4 | Completed | - | United States, Connecticut ... More >> Pfizer Investigational Site Hartford, Connecticut, United States, 06102 Less << |
NCT00673348 | - | Unknown | April 2010 | Korea, Republic of ... More >> St. Mary's Hospital Not yet recruiting Seoul, Korea, Republic of, 150-713 Contact: Dong-Gun Lee, M.D., Ph.D. 82-2-3779-1114 ext 1099 symonlee@catholic.ac.kr Principal Investigator: Dong-Gun Lee, M.D., Ph.D. St. Mary's Hospital Recruiting Seoul, Korea, Republic of, 150-713 Contact: Hae-Young Youn, Pharm D 82-2-3779-1114 ext 1216 baram@catholic.ac.kr Less << | |
NCT00940017 | - | Completed | - | - | |
NCT01207128 | Aspergillosis | Phase 2 | Withdrawn(None enrolled) | - | United States, Arkansas ... More >> UAMS Little Rock, Arkansas, United States, 72205 University of Arkansas Little Rock, Arkansas, United States, 72205 Less << |
NCT00647907 | Candidiasis|Cryptococcosis|Asp... More >>ergillosis Less << | PHASE4 | COMPLETED | 2025-05-04 | Pfizer Investigational Site, K... More >>aohsiung, Taiwan|Pfizer Investigational Site, Taichung, 40705, Taiwan|Pfizer Investigational Site, Taipei, 100, Taiwan|Pfizer Investigational Site, Taipei, 114, Taiwan Less << |
NCT00548262 | Candidemia In... More >>vasive Candidiasis Less << | Phase 4 | Completed | - | Brazil ... More >> Pfizer Investigational Site Brasilia, DF, Brazil, 70710-905 Pfizer Investigational Site Curitiba, PR, Brazil, 80060-900 Pfizer Investigational Site Rio de Janeiro, RJ, Brazil, 21941-913 Pfizer Investigational Site Porto Alegre, RS, Brazil, 90020-090 Pfizer Investigational Site Porto Alegre, RS, Brazil, 90110-270 Pfizer Investigational Site Sao Jose do Rio Preto, SP, Brazil, 15090-000 Chile Pfizer Investigational Site Independencia, Santiago, RM, Chile, 8380456 Colombia Pfizer Investigational Site Bogota DC, Cundinamarca, Colombia, 0000 Pfizer Investigational Site Cali, Valle Del Cauca, Colombia, 0000 Mexico Pfizer Investigational Site Leon, Guanajuato, Mexico, 37320 Pfizer Investigational Site Guadalajara, Jalisco, Mexico, 44280 Pfizer Investigational Site San Luis Potosi, Mexico, 78240 Panama Pfizer Investigational Site Panama, Panama Less << |
NCT03230058 | Infection, Fungal | Phase 2 Phase 3 | Recruiting | September 30, 2018 | India ... More >> GMRV Campus LV Prasad Eye Insitute Recruiting Visakhapatnam, Andhra Pradesh, India Contact: Merle Fernandes, MS merle@lvpei.org Contact: Antonio Di Zazzo, MD antoniodizazzo@gmail.com Less << |
NCT00833482 | Human Immunodeficiency Virus T... More >>ype 1 (HIV-1) HIV Infections Less << | Phase 1 | Completed | - | United States, California ... More >> West Coast Clinical Trials, Llc Cypress, California, United States, 90630 Netherlands Local Institution Nijmegen, Netherlands, 6425 GA Less << |
NCT00289991 | Antifungal Prophylaxis of Inva... More >>sive Fungal Infections Less << | Phase 3 | Completed | - | - |
NCT00159822 | Aspergillosis | PHASE2|PHASE3 | COMPLETED | 2025-12-08 | Pfizer Investigational Site, N... More >>antes, Cedex, 44093, France|Pfizer Investigational Site, Angers Cedex, 49033, France|Pfizer Investigational Site, Bobigny, 93000, France|Pfizer Investigational Site, Brest Cedex, 29609, France|Pfizer Investigational Site, Bris Sous Forges, 94640, France|Pfizer Investigational Site, Caen Cedex, 14033, France|Pfizer Investigational Site, Dinan Cedex, 22101, France|Pfizer Investigational Site, Grenoble Cedex 09, 38043, France|Pfizer Investigational Site, Lille Cedex, 59037, France|Pfizer Investigational Site, Lyon Cedex, 69394, France|Pfizer Investigational Site, Montpellier Cedex 5, 34295, France|Pfizer Investigational Site, Paris Cedex 18, 75877, France|Pfizer Investigational Site, Paris Cedex 20, 75970, France|Pfizer Investigational Site, Paris, 75010, France|Pfizer Investigational Site, Poitiers Cedex, 86021, France|Pfizer Investigational Site, Reims Cedex, 51092, France|Pfizer Investigational Site, Rouen Cedex, 76031, France|Pfizer Investigational Site, Suresnes, 92150, France Less << |
NCT00159822 | Aspergillosis | PHASE2|PHASE3 | COMPLETED | 2025-12-08 | Pfizer Investigational Site, N... More >>antes, Cedex, 44093, France|Pfizer Investigational Site, Angers Cedex, 49033, France|Pfizer Investigational Site, Bobigny, 93000, France|Pfizer Investigational Site, Brest Cedex, 29609, France|Pfizer Investigational Site, Bris Sous Forges, 94640, France|Pfizer Investigational Site, Caen Cedex, 14033, France|Pfizer Investigational Site, Dinan Cedex, 22101, France|Pfizer Investigational Site, Grenoble Cedex 09, 38043, France|Pfizer Investigational Site, Lille Cedex, 59037, France|Pfizer Investigational Site, Lyon Cedex, 69394, France|Pfizer Investigational Site, Montpellier Cedex 5, 34295, France|Pfizer Investigational Site, Paris Cedex 18, 75877, France|Pfizer Investigational Site, Paris Cedex 20, 75970, France|Pfizer Investigational Site, Paris, 75010, France|Pfizer Investigational Site, Poitiers Cedex, 86021, France|Pfizer Investigational Site, Reims Cedex, 51092, France|Pfizer Investigational Site, Rouen Cedex, 76031, France|Pfizer Investigational Site, Suresnes, 92150, France Less << |
NCT00143312 | Prophylaxis Of Invasive Fungal... More >> Infections Less << | Phase 4 | Completed | - | Belgium ... More >> Pfizer Investigational Site Leuven, Belgium, 3000 France Pfizer Investigational Site Marseille, Cedex 09, France, 13273 Pfizer Investigational Site Creteil, France, 94010 Pfizer Investigational Site Nantes, France, 44035 cedex Pfizer Investigational Site Pessac, France, 33600 Pfizer Investigational Site Strasbourg, France, 67098 Germany Pfizer Investigational Site Koeln, Germany, 50937 Pfizer Investigational Site Mainz, Germany, 55101 Pfizer Investigational Site Wuerzburg, Germany, 97070 Portugal Pfizer Investigational Site Lisboa, Portugal, 1099-023 Spain Pfizer Investigational Site Barcelona, Spain, 08025 Pfizer Investigational Site Barcelona, Spain, 08036 Pfizer Investigational Site Madrid, Spain, 28006 Sweden Pfizer Investigational Site Stockholm, Sweden, 141 86 Switzerland Pfizer Investigational Site CH-4031 Basel, Switzerland United Kingdom Pfizer Investigational Site London, United Kingdom, W12 0NN Pfizer Investigational Site Manchester, United Kingdom, M20 4BX Less << |
NCT00548262 | - | Completed | - | - | |
NCT00289991 | - | Completed | - | - | |
NCT00136968 | Fungal Infection | PHASE1 | COMPLETED | 2025-05-05 | - |
NCT03515382 | Healthy | Phase 1 | Completed | - | United Kingdom ... More >> Quotient Sciences Limited Ruddington, United Kingdom Less << |
NCT00833482 | - | Completed | - | - | |
NCT00143312 | - | Completed | - | - | |
NCT00150345 | Possible Fungal Infection | Phase 3 | Completed | - | Germany ... More >> Pfizer Investigational Site Augsburg, Germany, 86156 Pfizer Investigational Site Berlin, Germany, 10117 Pfizer Investigational Site Berlin, Germany, 12200 Pfizer Investigational Site Berlin, Germany, 13353 Pfizer Investigational Site Bielefeld, Germany, 33611 Pfizer Investigational Site Bremen, Germany, 28177 Pfizer Investigational Site Chemnitz, Germany, 09113 Pfizer Investigational Site Dresden, Germany, 01307 Pfizer Investigational Site Erlangen, Germany, 91054 Pfizer Investigational Site Essen, Germany, 45239 Pfizer Investigational Site Frankfurt (Oder), Germany, 15236 Pfizer Investigational Site Freiburg, Germany, 79106 Pfizer Investigational Site Goettingen, Germany, 37075 Pfizer Investigational Site Hannover, Germany, 30623 Pfizer Investigational Site Homburg/Saar, Germany, 66421 Pfizer Investigational Site Kiel, Germany, 24116 Pfizer Investigational Site Koeln, Germany, 50937 Pfizer Investigational Site Leipzig, Germany, 04103 Pfizer Investigational Site Ludwigshafen, Germany, 67063 Pfizer Investigational Site Luebeck, Germany, 23538 Pfizer Investigational Site Mainz, Germany, 55101 Pfizer Investigational Site Muenchen, Germany, 81675 Pfizer Investigational Site Muenchen, Germany, 81737 Pfizer Investigational Site Potsdam, Germany, 14467 Pfizer Investigational Site Stuttgart, Germany, 70376 Pfizer Investigational Site Trier, Germany, 54290 Pfizer Investigational Site Wiesbaden, Germany, 65191 Pfizer Investigational Site Wuerzburg, Germany, 97070 Less << |
NCT01418846 | - | Completed | - | Belgium ... More >> Ghent University Hospital - Cystic Fibrosis Clinic Ghent, East Flanders, Belgium, 9000 University Hospitals Leuven Leuven, Vlaams-Brabant, Belgium, 3000 University Hospital Brussels - Cystic Fibrosis Clinic Brussels, Belgium, 1090 Less << | |
NCT00238355 | - | Terminated(competing study at ... More >>site) Less << | - | - | |
NCT00150345 | - | Completed | - | - | |
NCT01657201 | Systemic Mycotic Infection | Phase 1 | Completed | - | Korea, Republic of ... More >> Clinical Research Institute, Seoul National University Hospital Seoul, Korea, Republic of Less << |
NCT00942773 | Healthy | PHASE1 | COMPLETED | 2025-03-09 | Seoul National University Hosp... More >>ital Clinical Trial Center, Seoul, 110-744, Korea, Republic of Less << |
NCT02074462 | - | Completed | - | Netherlands ... More >> University Medical Center Groningen Groningen, Netherlands, 9700 RB Less << | |
NCT00174473 | Neutropenia | PHASE1|PHASE2 | COMPLETED | 2025-08-05 | - |
NCT00745992 | - | Unknown | July 2011 | Taiwan ... More >> National Taiwan University Hospital Not yet recruiting Taipei, Taiwan, 100 Contact: Shu-Wen Lin, PharmD, MS 886-2-2312-3456 ext 88408 shuwenlin@ntu.edu.tw Contact: Fe-Lin L. Wu, Ph.D. 886-2-2312-3456 ext 88389 flwu@ntu.edu.tw Principal Investigator: Shu-Wen Lin, PharmD, MS Sub-Investigator: Fe-Lin L. Wu, Ph.D. Less << | |
NCT00075803 | Lymphoma Infe... More >>ction Leukemia Less << | Phase 3 | Completed | - | - |
NCT00620074 | - | Terminated(See Detailed Descri... More >>ption) Less << | - | - | |
NCT00075803 | - | Completed | - | - | |
NCT00997035 | - | Completed | - | - | |
NCT00997035 | Corneal Ulcer ... More >> Eye Infections, Fungal Less << | Phase 3 | Completed | - | United States, California ... More >> Proctor Foundation, UCSF San Francisco, California, United States, 94143 India Aravind Eye Hospital Coimbatore, Tamil Nadu, India Aravind Eye Hospitals Madurai, Tamil Nadu, India Aravind Eye Hospital Pondicherry, Tamil Nadu, India Aravind Eye Hospital Tirunelveli, Tamil Nadu, India Nepal Bharatpur Eye Hospital Bharatpur, Chitwan, Nepal Lumbini Eye Institute Bhairahawa, Lumbini, Nepal Less << |
NCT01418833 | - | Completed | - | Belgium ... More >> University Hospitals Leuven Leuven, Vlaams-Brabant, Belgium, 3000 Less << | |
NCT00620074 | Aspergillosis | Phase 4 | Terminated(See Detailed Descri... More >>ption) Less << | - | United States, Georgia ... More >> Pfizer Investigational Site Atlanta, Georgia, United States, 30322 United States, Michigan Pfizer Investigational Site Detroit, Michigan, United States, 48202 United States, Texas Pfizer Investigational Site Fort Worth, Texas, United States, 76104 Pfizer Investigational Site Fort Worth, Texas, United States, 76107 Less << |
NCT01104376 | Efavirenz, Metabolism and Phar... More >>macokinetics Changes Less << | Not Applicable | Completed | - | United States, Indiana ... More >> Indiana University Indianapolis, Indiana, United States, 46202 Less << |
NCT00836875 | Invasive Aspergillosis | PHASE3 | TERMINATED | 2025-05-13 | Childrens Hospital Los Angeles... More >>, Los Angeles, California, 90027, United States|Children's Hospital & Research Center Oakland (CHRCO), Oakland, California, 94609, United States|Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, 15224, United States|The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, United States|Children's Pavilion, Virginia Commonwealth University Health System, Richmond, Virginia, 23219, United States|Virginia Commonwealth University Health System, Hospital Pharmacy, Richmond, Virginia, 23298-0042, United States|Pediatric Hematology and Oncology, Virginia Commonwealth University Health System, Richmond, Virginia, 23298, United States|Virginia Commonwealth University/MCV Clinical Pathology, Richmond, Virginia, 23298, United States|Virginia Commonwealth University, Richmond, Virginia, 23298, United States|Alberta Children's Hospital, Pediatric Oncology Office, Calgary, Alberta, T3B 6A8, Canada|Alberta Children's Hospital, Calgary, Alberta, T3B 6A8, Canada|Fakultni nemocnice Brno, Brno, 625 00, Czechia|Fakultni nemocnice Brno, Brno, 62500, Czechia|UMC St. Radboud, Nijmegen, 6500 HB, Netherlands|Klinika Transplantacji Szpiku, Onkologii i Hematologii Dzieciecej, Wroclaw, 50-345, Poland|National University Hospital, Singapore, 119074, Singapore|KK Women's and Children's Hospital, Singapore, 229899, Singapore|Hospital General Universitari Vall D'Hebron, Barcelona, 08035, Spain|Hospital Universitari Vall d'Hebron. Servicio de Farmacia, Barcelona, 08035, Spain|Hospital Universitario Vall d'Hebron, Barcelona, 08035, Spain|HOSPITAL UNIVERSITARIO 12 DE OCTUBRE Servicio de Farmacia, Madrid, 28041, Spain|Hospital Universitario 12 de Octubre, Madrid, 28041, Spain|Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok noi, Bangkok, 10700, Thailand|Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Patumwan, Bangkok, 10330, Thailand|Department of Pediatrics, Phramongkutklao hospital, Rajathevee, Bangkok, 10400, Thailand Less << |
NCT00238355 | Infection Uns... More >>pecified Adult Solid Tumor, Protocol Specific Less << | Phase 2 | Terminated(competing study at ... More >>site) Less << | - | United States, Oregon ... More >> OHSU Knight Cancer Institute Portland, Oregon, United States, 97239-3098 Less << |
NCT02631954 | Aspergillus Infections ... More >> Candida Infections Fungal Infections Less << | Phase 1 | Completed | - | Korea, Republic of ... More >> Inha University Hospital Jung-gu, Incheon, Korea, Republic of, 22332 Less << |
NCT02912156 | Fungus Infection | Phase 4 | Completed | - | - |
NCT01080651 | Invasive Aspergillosis | PHASE1 | COMPLETED | 2025-03-09 | Seoul National University Hosp... More >>ital Clinical Trial Center, Seoul, Korea, Republic of Less << |
NCT00836875 | Invasive Aspergillosis | PHASE3 | TERMINATED | 2025-05-13 | Childrens Hospital Los Angeles... More >>, Los Angeles, California, 90027, United States|Children's Hospital & Research Center Oakland (CHRCO), Oakland, California, 94609, United States|Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, 15224, United States|The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, United States|Children's Pavilion, Virginia Commonwealth University Health System, Richmond, Virginia, 23219, United States|Virginia Commonwealth University Health System, Hospital Pharmacy, Richmond, Virginia, 23298-0042, United States|Pediatric Hematology and Oncology, Virginia Commonwealth University Health System, Richmond, Virginia, 23298, United States|Virginia Commonwealth University/MCV Clinical Pathology, Richmond, Virginia, 23298, United States|Virginia Commonwealth University, Richmond, Virginia, 23298, United States|Alberta Children's Hospital, Pediatric Oncology Office, Calgary, Alberta, T3B 6A8, Canada|Alberta Children's Hospital, Calgary, Alberta, T3B 6A8, Canada|Fakultni nemocnice Brno, Brno, 625 00, Czechia|Fakultni nemocnice Brno, Brno, 62500, Czechia|UMC St. Radboud, Nijmegen, 6500 HB, Netherlands|Klinika Transplantacji Szpiku, Onkologii i Hematologii Dzieciecej, Wroclaw, 50-345, Poland|National University Hospital, Singapore, 119074, Singapore|KK Women's and Children's Hospital, Singapore, 229899, Singapore|Hospital General Universitari Vall D'Hebron, Barcelona, 08035, Spain|Hospital Universitari Vall d'Hebron. Servicio de Farmacia, Barcelona, 08035, Spain|Hospital Universitario Vall d'Hebron, Barcelona, 08035, Spain|HOSPITAL UNIVERSITARIO 12 DE OCTUBRE Servicio de Farmacia, Madrid, 28041, Spain|Hospital Universitario 12 de Octubre, Madrid, 28041, Spain|Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok noi, Bangkok, 10700, Thailand|Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Patumwan, Bangkok, 10330, Thailand|Department of Pediatrics, Phramongkutklao hospital, Rajathevee, Bangkok, 10400, Thailand Less << |
NCT01073618 | - | Completed | - | - | |
NCT00904995 | Leukemia Fung... More >>al Infection Less << | Phase 3 | Completed | - | United States, Texas ... More >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Less << |
NCT01104376 | - | Completed | - | - | |
NCT00904995 | - | Completed | - | - | |
NCT00152594 | Leukemia, Myelocytic, Acute | Phase 3 | Terminated | - | Germany ... More >> Johann Wolfgang Goethe-Universität Frankfurt am Main Frankfurt am Main, Germany, 60590 Universitätsklinikum Mannheim, Universität Heidelberg Heidelberg, Germany, 68305 Klinikum der Universität Köln Köln, Germany, 50931 Less << |
NCT00739934 | Candidiasis C... More >>andidemia Less << | Phase 2 | Completed | - | United States, Arizona ... More >> Pfizer Investigational Site Tucson, Arizona, United States, 85719 Pfizer Investigational Site Tucson, Arizona, United States, 85724 United States, California Pfizer Investigational Site Orange, California, United States, 92868 United States, Florida Pfizer Investigational Site Jacksonville, Florida, United States, 32207 United States, Georgia Pfizer Investigational Site Atlanta, Georgia, United States, 30322-1062 Pfizer Investigational Site Atlanta, Georgia, United States, 30322 Pfizer Investigational Site Atlanta, Georgia, United States, 30342-1600 United States, Louisiana Pfizer Investigational Site New Orleans, Louisiana, United States, 70118 United States, Maryland Pfizer Investigational Site Baltimore, Maryland, United States, 21215 United States, North Carolina Pfizer Investigational Site Durham, North Carolina, United States, 27710 United States, Ohio Pfizer Investigational Site Cleveland, Ohio, United States, 44106 United States, Oregon Pfizer Investigational Site Portland, Oregon, United States, 97239 United States, Tennessee Pfizer Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas Pfizer Investigational Site Houston, Texas, United States, 77030 Less << |
NCT01073631 | - | Completed | - | - | |
NCT01073618 | - | Completed | - | - | |
NCT00531479 | - | Completed | - | - | |
NCT01782131 | Fungal Infections | Phase 3 | Recruiting | September 16, 2019 | - |
NCT00531479 | Aspergillosis | Phase 3 | Completed | - | - |
NCT01073631 | - | Completed | - | - | |
NCT00890708 | Mycoses | Not Applicable | Completed | - | Korea, Republic of ... More >> Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Less << |
NCT02906176 | Healthy Volunteers | Phase 1 | Completed | - | Korea, Republic of ... More >> Seoul National University Hospital Clinical Trial Center Seoul, Korea, Republic of Less << |
NCT01416025 | - | Completed | - | - | |
NCT01148160 | - | Terminated | - | Korea, Republic of ... More >> Asan Medical Center, University of Ulsan College of Medicine Seoul, Korea, Republic of, 138-736 Less << | |
NCT01383993 | - | Completed | - | - | |
NCT01137292 | - | Completed | - | - | |
NCT00739934 | - | Completed | - | - | |
NCT01137292 | - | Completed | - | - | |
NCT00556998 | Pharmacokinetics | PHASE2 | COMPLETED | 2025-12-09 | Pfizer Investigational Site, C... More >>hicago, Illinois, 60637, United States|Pfizer Investigational Site, New Orleans, Louisiana, 70118, United States|Pfizer Investigational Site, Durham, North Carolina, 27705, United States|Pfizer Investigational Site, Cleveland, Ohio, 44106, United States|Pfizer Investigational Site, Portland, Oregon, 97239, United States|Pfizer Investigational Site, Nashville, Tennessee, 37232-2195, United States|Pfizer Investigational Site, Nashville, Tennessee, 37232, United States|Pfizer Investigational Site, Fort Worth, Texas, 76104-2796, United States|Pfizer Investigational Site, Houston, Texas, 77030, United States Less << |
NCT00556998 | Pharmacokinetics | PHASE2 | COMPLETED | 2025-12-09 | Pfizer Investigational Site, C... More >>hicago, Illinois, 60637, United States|Pfizer Investigational Site, New Orleans, Louisiana, 70118, United States|Pfizer Investigational Site, Durham, North Carolina, 27705, United States|Pfizer Investigational Site, Cleveland, Ohio, 44106, United States|Pfizer Investigational Site, Portland, Oregon, 97239, United States|Pfizer Investigational Site, Nashville, Tennessee, 37232-2195, United States|Pfizer Investigational Site, Nashville, Tennessee, 37232, United States|Pfizer Investigational Site, Fort Worth, Texas, 76104-2796, United States|Pfizer Investigational Site, Houston, Texas, 77030, United States Less << |
NCT03672292 | Invasive Pulmonary Aspergillos... More >>is Less << | Phase 2 | Not yet recruiting | October 2020 | - |
NCT01416025 | Fungal Infection | Phase 4 | Completed | - | United States, Maryland ... More >> Johns Hopkins Baltimore, Maryland, United States, 21205 Less << |
NCT01812473 | - | Completed | - | Belgium ... More >> University Hospitals Leuven Leuven, Vlaams-Brabant, Belgium, 3000 Less << | |
NCT01812473 | - | Completed | - | - | |
NCT02227797 | Fungal Infection | PHASE1 | COMPLETED | 2019-03-01 | University of Minnesota Medica... More >>l Center, Fairview, Minneapolis, Minnesota, 55455, United States Less << |
NCT01092832 | - | Terminated(This protocol termi... More >>nated prematurely on July 8, 2013 due to slow enrollment, not because of any safety issues or concerns.) Less << | - | - | |
NCT01480219 | - | Completed | - | - | |
NCT01383993 | Aspergillosis, Aspergilloma | Phase 2 | Completed | - | Japan ... More >> Japanese Red Cross Nagoya Daiichi Hospital Nagoya, Aichi, Japan National hospital Organization Nagoya Medical Center Nagoya, Aichi, Japan Sapporo Hokuyu Hosipital Sapporo, Hokkaido, Japan Kanagawa Children's Medical Center Yokohama, Kanagawa, Japan Osaka Medical Center and Research Institute for Maternal and Child Health Izumi, Osaka, Japan Dokkyo Medical University Hospital Shimotsuga-gun, Tochigi, Japan Less << |
NCT01188759 | Aspergillosis ... More >> Invasive Pulmonary Aspergillosis Neuroaspergillosis Less << | Phase 3 | Withdrawn | August 2014 | - |
NCT00893555 | Invasive Fungal Infection ... More >> Hematological Malignancy Less << | Phase 3 | Completed | - | Netherlands ... More >> University Medical Center Groningen Groningen, Netherlands, 9713GZ Less << |
NCT01092832 | Candidiasis | Phase 3 | Terminated(This protocol termi... More >>nated prematurely on July 8, 2013 due to slow enrollment, not because of any safety issues or concerns.) Less << | - | China, Hubei ... More >> Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan, Hubei, China, 430030 China Beijing Children's Hospital, Capital University of Medical Sciences Beijing, China, 100045 Czech Republic Fakultni nemocnice Brno - Klinika detske onkologie Brno, Czech Republic, 625 00 Hong Kong Department of Paediatrics and Adolescent Medicine Hong Kong, Hong Kong, 0 Queen Mary Hospital Hong Kong, Hong Kong The Chinese University of Hong Kong, Prince of Wales Hospital Shatin, N.T., Hong Kong Hungary Semmelweis Egyetem, II. sz. Szemeszeti Klinika Budapest, Hungary, 1085 Semmelweis Egyetem, II. sz. Gyermekgyogyaszati Klinika Budapest, Hungary, 1094 Fovarosi Onkormanyzat Egyesitett Szent Istvan és Szent Laszlo Korhaz-Rendelointezet Budapest, Hungary, 1097 Mexico Instituto Nacional de Pediatria Colonia Insurgentes Cuicuilco, Delegacion Coyoacan, DF, Mexico, 04530 Philippines Medical Research Laboratory Philippine General Hospital University of the Philippines Ermita,, Manila, Philippines, 1000 Rm. 112 ICHHD, National Institutes of Health-University of the Philippines Manila Manila, Philippines, 1000 Poland Oddzial Pediatryczny I- Hematologiczno-Onkologiczny Olsztyn, Poland, 10-561 Slovakia Detska fakultna nemocnica s poliklinikou Bratislava Bratislava, Slovakia, 833 40 Less << |
NCT01539330 | Healthy | Phase 4 | Completed | - | Austria ... More >> Medical University of Vienna, Department of Clinical Pharmacology Vienna, Austria, 1090 Less << |
NCT00792246 | Graft Versus Host Disease ... More >> Stem Cell Transplantation Less << | Phase 1 | Completed | - | United States, North Carolina ... More >> Duke University Medical Center Durham, North Carolina, United States, 27710 Less << |
NCT02689713 | Pain Thermal ... More >>Injury Burns Hyperalgesia Less << | Phase 2 | Recruiting | June 2020 | United States, Texas ... More >> San Antonio Military Medical Center Recruiting San Antonio, Texas, United States, 78234 Contact: Christopher White, MD christopher.e.white34.mil@mail.mil Less << |
NCT00300677 | Infections, Fungal | Phase 4 | Completed | - | United States, Massachusetts ... More >> Pfizer Investigational Site Belmont, Massachusetts, United States, 02478-1041 Less << |
NCT00300677 | - | Completed | - | - | |
NCT01185405 | Invasive Fungal Infection | Not Applicable | Withdrawn | December 2013 | Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Less << |
NCT02396225 | Invasive Aspergillosis | TERMINATED | 2025-12-16 | Aarhus University Hospital, Aa... More >>rhus C, 8000, Denmark Less << | |
NCT00855101 | Healthy Volunteers | Phase 1 | Completed | - | Belgium ... More >> Pfizer Investigational Site Bruxelles, Belgium, 1070 Less << |
NCT01480219 | - | Completed | - | - | |
NCT03760276 | Fungal Infection | Phase 1 | Completed | - | Korea, Republic of ... More >> Seoul National University Hospital Clinical Trial Center Seoul, Korea, Republic of, 03080 Less << |
NCT03731169 | Aspergillosis Invasive ... More >> Fungal Infection Less << | Phase 4 | Recruiting | June 2019 | Canada, Ontario ... More >> Toronto General Hospital Recruiting Toronto, Ontario, Canada, M5G 2C4 Princess Margaret Cancer Care Centre Recruiting Toronto, Ontario, Canada, M5G 2M9 Less << |
NCT02283905 | Blastomycosis | Phase 4 | Suspended(Manufacturer of amph... More >>otericin-B deoxycholate cannot supply at this time.) Less << | December 2018 | Canada, Manitoba ... More >> St. Boniface General Hospital Winnipeg, Manitoba, Canada, R2H 2A6 Less << |
NCT01101386 | Fungal Infection | COMPLETED | 2025-11-12 | University of Colorado Hospita... More >>l, Aurora, Colorado, 80045, United States Less << | |
NCT03067350 | - | Recruiting | October 2018 | France ... More >> University Hospital, Grenoble Alpes Recruiting Grenoble, France, 38043 Less << | |
NCT01030653 | Healthy | Phase 4 | Completed | - | United States, New Jersey ... More >> TKL Research Inc Paramus, New Jersey, United States, 07652 Less << |
NCT01030653 | - | Completed | - | - | |
NCT02904434 | - | Recruiting | June 2020 | United States, Pennsylvania ... More >> Children's Hospital of Philadelphia Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Athena Zuppa, MD 267-426-7359 zuppa@email.chop.edu Contact: Nicole Zane, PharmD, PhD 215.590.8797 zanen@email.chop.edu Less << | |
NCT01660334 | Scedosporium Infection | COMPLETED | 2025-05-12 | - | |
NCT01151085 | Systemic Mycosis | COMPLETED | 2025-05-12 | - | |
NCT02100761 | Invasive Pulmonary Aspergillos... More >>is Less << | UNKNOWN | 2025-06-15 | Qilu Hospital, Jinan, Shandong... More >>, 250012, China Less << | |
NCT01976078 | - | Completed | - | United States, California ... More >> Children's Hospital Los Angeles Los Angeles, California, United States, 90027 Less << | |
NCT01151085 | Systemic Mycosis | COMPLETED | 2025-05-12 | - | |
NCT01887457 | Immunocompromised Patient ... More >> Aspergillosis Fusarium Less << | Phase 2 | Suspended(Transfer of manageme... More >>nt of study) Less << | December 2016 | United Kingdom ... More >> The Christie NHS Foundation Trust Manchester, United Kingdom, M20 4BX Less << |
NCT02234739 | Invasive Pulmonary Aspergillos... More >>is|COPD Less << | PHASE4 | UNKNOWN | 2025-12-16 | Hangzhou Red Cross Hospital, H... More >>angzhou, Zhejiang, 310003, China Less << |
NCT03260634 | Voriconazole|Fungal Infection | UNKNOWN | 2018-01-01 | Chulalongkorn university, Bang... More >>kok, 10330, Thailand Less << | |
NCT01660334 | Scedosporium Infection | COMPLETED | 2025-05-12 | - | |
NCT02110316 | Voriconazole ... More >>Bioavailability Critically Ill Less << | Phase 4 | Withdrawn(no eligible patients... More >>; study stopped without inclusion) Less << | - | Netherlands ... More >> University Medical Center Groningen Groningen, Netherlands, 9700 RB Less << |
NCT04743544 | Adverse Drug Reactions | UNKNOWN | 2022-10-31 | Dokuz Eylul University Hospita... More >>l, ?zmir, 35330, Turkey Less << | |
NCT03827278 | Talaromyces in Human Immunodef... More >>iciency Virus Negative|To Compare Voriconazole and Amphotericin Sequential Itraconazole Therapy|To Dynamically Monitor the Anti-Interferon-γ Autoantibodies Less << | UNKNOWN | 2021-12-30 | Guangxi Medical University, Na... More >>nning, Guangxi, 530021, China Less << | |
NCT04547335 | Adverse Drug Reactions | UNKNOWN | 2022-10-31 | Dokuz Eylul University Hospita... More >>l, ?zmir, 35340, Turkey Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.86mL 0.57mL 0.29mL |
14.31mL 2.86mL 1.43mL |
28.63mL 5.73mL 2.86mL |
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Dissolving Methods |
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound. Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
|