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Chemical Structure| 137862-53-4 Chemical Structure| 137862-53-4

Structure of Valsartan
CAS No.: 137862-53-4

Chemical Structure| 137862-53-4

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Valsartan is a selective angiotensin II AT1 receptor antagonist with elimination half-life‎ of ‎6 hours.

Synonyms: CGP 48933

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Product Details of Valsartan

CAS No. :137862-53-4
Formula : C24H29N5O3
M.W : 435.52
SMILES Code : CC(C)[C@H](N(CC1=CC=C(C2=CC=CC=C2C3=NN=NN3)C=C1)C(CCCC)=O)C(O)=O
Synonyms :
CGP 48933
MDL No. :MFCD00865840

Safety of Valsartan

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H336-H361
Precautionary Statements:P201-P202-P261-P271-P280-P304+P340+P312-P308+P313-P403+P233-P405-P501

Related Pathways of Valsartan

GPCR

Isoform Comparison

Biological Activity

Target
  • AT2 receptor

In Vitro:

Cell Line
Concentration Treated Time Description References
AML-12 cells 20µM 12 hours To investigate the effect of Sac/Val on FGF21 expression in AML-12 cells, results showed that Sac/Val upregulated FGF21 expression via PPARα PMC11847388
H9C2 cells 20µM 12 hours To investigate the effect of Sac/Val on FGF21 expression in H9C2 cells under hypoxic conditions, results showed that Sac/Val significantly upregulated FGF21 expression PMC11847388
NIH-3T3 cells (induced as CAFs) 5 μg/ml Val and 0.5 μg/ml DOX 72 hours Regulate CAFs activity and reduce collagen expression PMC10904913
4T1 tumor cells 5 μg/ml Val and 0.5 μg/ml DOX 72 hours Induce tumor cell senescence and inhibit proliferation and migration PMC10904913
Human aortic endothelial cells (HAECs) 10 μM Valsartan + 15–240 μg/mL IS 18 hours Valsartan significantly increased nitrite levels in HAECs, while IS at 60–240 μg/mL significantly decreased valsartan-induced nitrite production in a dose-dependent manner. PMC6974788
Primary cortico-hippocampal neurons 100 μM 24 hours Inhibited oligomerization of Aβ1–42 into high-molecular-weight (HMW) soluble oligomers PMC2040315

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
C57BL/6 mice Subtotal nephrectomy (SNx) mice Oral (Valsartan) and intraperitoneal (IS) 60 mg/kg/day Valsartan daily, IS thrice a week for six weeks Valsartan significantly improved blood flow reperfusion and CD31+ capillary density in ischemic limbs of SNx mice, while IS attenuated the protective effect of valsartan. Cotreatment with apocynin and calphostin C reversed the IS-mediated inhibition of valsartan-induced neovascularization. PMC6974788
Transgenic TG(mRen2)27(Ren2) rats Hypertension and non-alcoholic fatty liver disease model Oral 30 mg/kg/day Once daily for 3 weeks To evaluate the effects of valsartan on hypertension and non-alcoholic fatty liver disease. Results showed that valsartan significantly attenuated hepatic oxidative stress, steatosis, inflammation, and fibrosis. PMC2683586
Mice Myocardial infarction model Oral gavage 52 mg/kg/day Once daily for 14 days To investigate the effect of Sac/Val on cardiac function, fibrosis, and oxidative stress in MI mice, results showed that Sac/Val improved cardiac function and reduced fibrosis and oxidative stress by upregulating FGF21 expression PMC11847388
Mice Tg2576 AD model mice Oral administration via drinking water 10 or 40 mg/kg/d Approximately 5 months of continuous treatment Reduced brain HMW Aβ oligomers, improved spatial learning deficits, and attenuated amyloid plaque pathology PMC2040315
BALB/c mice 4T1 tumor model Intravenous injection 40 mg/kg Dosing interval not specified, continued until tumor volume endpoint Significantly inhibits tumor growth and lung metastasis, extends survival PMC10904913
Transgenic Ren2 rats Transgenic Ren2 rat model Intraperitoneal injection 30 mg/kg/day Once daily for 21 days To evaluate the effects of Valsartan on myocardial hypertrophy and fibrosis in transgenic Ren2 rats. Results showed that Valsartan significantly reduced systolic blood pressure and serum aldosterone levels, and improved markers of myocardial hypertrophy and fibrosis. PMC3640616
Mice High-fat diet-induced type 2 diabetes model and db/db mice model Drinking water 10 mg/kg/day Once daily for 8 weeks To investigate the effects of valsartan alone or in combination with vildagliptin in a mouse model of type 2 diabetes. Results showed that combination therapy significantly improved glucose metabolism, insulin sensitivity, reduced inflammatory markers, and ameliorated hepatic steatosis and pancreatic beta-cell function. PMC4176757
C57BL/6J mice Experimental acute myocardial infarction model Oral gavage 20 mg/kg BW/day Once daily for 28 days To investigate the effect of LCZ696 on cardiac rupture and survival rate after acute myocardial infarction. Results showed that LCZ696 significantly reduced the incidence of cardiac rupture and improved survival rate. PMC6059351
Mice Diabetic cardiomyopathy model Subcutaneous osmotic minipumps 2 mg/kg Replaced every 4 weeks for 10 weeks Prevented diabetes-induced cardiac dysfunction, reduced oxidative stress and cardiomyocyte apoptosis PMC3830441

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00190580 Chronic Kidney Disease ... More >> Hypertension Less << Phase 4 Completed - Japan ... More >> St. Marianna University School of Medicine Kawasaki, Kanagawa, Japan, 216-8511 Less <<
NCT00386607 Hypertension Phase 3 Completed - United States, California ... More >> Investigative Centers San Diego, California, United States Canada Investigative Centers Canada, Canada Germany Investigative Centers Germany, Germany Netherlands Investigative Centers Netherlands, Netherlands Less <<
NCT00386607 - Completed - -
NCT01406431 Hyperlipidemia ... More >> Hypertension Less << Phase 1 Completed - Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of Less <<
NCT01129557 Proteinuric Kidney Disease ... More >> Diabetic Nephropathy Hypertensive Nephrosclerosis IgA Nephropathy Focal Segmental Glomerulosclerosis Glomerulopathy (Obesity-associated) Glomerulonephritis, Membranous Less << Phase 4 Terminated - United States, New York ... More >> Columbia University Medical Center New York, New York, United States, 10032 Less <<
NCT02415192 - Unknown November 2016 Korea, Republic of ... More >> LG Life Science Recruiting Seoul, Jongno gu, Korea, Republic of, 110-783 Contact: Hye jin Yoon Less <<
NCT01129557 - Terminated - -
NCT03279861 Congestive Heart Failure ... More >> Hypertension Less << Phase 4 Withdrawn(protocol change) November 2019 -
NCT00277472 Hypertension Phase 4 Completed - United States, New Jersey ... More >> Novartis East Hanover, New Jersey, United States, 07936 Less <<
NCT00687206 Hypertension ... More >>Ventricular Remodeling Erectile Dysfunctions Less << Phase 4 Completed - Italy ... More >> Department of internal medicine University Federico II Naples, Italy, 80131 Less <<
NCT00367939 Hypertension Phase 3 Completed - Germany ... More >> Investigative Centers, Germany Less <<
NCT00523549 Hypertension ... More >>Diastolic Dysfunction Less << Phase 4 Completed - United States, New Jersey ... More >> Novartis Investigative Sites USA, New Jersey, United States Less <<
NCT00523549 - Completed - -
NCT02970669 Heart Failure, Reduced Ejectio... More >>n Fraction Less << Phase 4 Completed - United States, Alabama ... More >> Novartis Investigative Site Fort Payne, Alabama, United States, 35967 United States, California Novartis Investigative Site Beverly Hills, California, United States, 90211 Novartis Investigative Site Stockton, California, United States, 95204 Novartis Investigative Site West Hills, California, United States, 91307 United States, Florida Novartis Investigative Site Doral, Florida, United States, 33126 Novartis Investigative Site Inverness, Florida, United States, 34452 Novartis Investigative Site Ormond Beach, Florida, United States, 32174 Novartis Investigative Site Port Orange, Florida, United States, 32127 United States, Maryland Novartis Investigative Site Lutherville, Maryland, United States, 21093 United States, New Jersey Novartis Investigative Site East Brunswick, New Jersey, United States, 08816 Novartis Investigative Site Ridgewood, New Jersey, United States, 07450 United States, South Carolina Novartis Investigative Site Columbia, South Carolina, United States, 29203 Novartis Investigative Site Greenville, South Carolina, United States, 29615 Novartis Investigative Site Lancaster, South Carolina, United States, 29720 United States, Texas Novartis Investigative Site Allen, Texas, United States, 75002-3688 Novartis Investigative Site McKinney, Texas, United States, 75013 Novartis Investigative Site New Braunfels, Texas, United States, 78130 Novartis Investigative Site San Antonio, Texas, United States, 78229 Novartis Investigative Site San Marcos, Texas, United States, 78666 Novartis Investigative Site Sherman, Texas, United States, 75092 Novartis Investigative Site Tomball, Texas, United States, 77375 United States, Virginia Novartis Investigative Site Midlothian, Virginia, United States, 23114 United States, Washington Novartis Investigative Site Tacoma, Washington, United States, 98405 Less <<
NCT01415505 Hypertension Phase 3 Completed - -
NCT00523744 Hypertension Phase 3 Completed - Germany ... More >> Novartis Investigative Site, , Germany Schwerin, Germany Less <<
NCT00698646 Hypertension Phase 4 Completed - United States, Alabama ... More >> Investigative site Birmingham, Alabama, United States United States, Arizona Investigative site Phoenix, Arizona, United States United States, California Investigative Site Escondido, California, United States Investigative site Fresno, California, United States Investigative site Huntington Park, California, United States Investigative Sites Pismo Beach, California, United States United States, Florida Investigative site Miami, Florida, United States Investigative site Ormond Beach, Florida, United States United States, Georgia Investigative site Conyers, Georgia, United States United States, Kentucky Investigative Site Lexington, Kentucky, United States United States, Maine Investigative site Portland, Maine, United States United States, Nevada Investigative site Las Vegas, Nevada, United States United States, New York Investigative site Buffalo, New York, United States United States, North Carolina Investigative site Shelby, North Carolina, United States United States, Ohio Investigative site Carlisle, Ohio, United States United States, Oklahoma Investigative site Oklahoma City, Oklahoma, United States United States, Pennsylvania Investigative site Erie, Pennsylvania, United States United States, South Carolina Investigative Site Greer, South Carolina, United States Investigative Site Taylors, South Carolina, United States United States, Utah Investigative site St George, Utah, United States Less <<
NCT00523744 - Completed - -
NCT00698646 - Completed - -
NCT02069821 Healthy Phase 1 Completed - Korea, Republic of ... More >> Chungnam national university hospital Daejeon, Jung-gu, Korea, Republic of, 301-721 Less <<
NCT00874601 Acute Ischemic Stroke Phase 4 Unknown July 2012 Korea, Republic of ... More >> Hallym University Sacred Heart Hospital Recruiting Anyang, Gyeonggi, Korea, Republic of, 430-070 Contact: Byung-chul Lee, MD, PhD    +82-31-380-3741    ssbrain@hallym.ac.kr    Sub-Investigator: Kyung-ho Yu, MD, PhD Less <<
NCT02519010 Healthy Phase 1 Completed - Egypt ... More >> Genuine Research Center GRC Cairo, Egypt Less <<
NCT00550095 Microalbuminuria ... More >> Proteinuria Less << Phase 4 Completed - Egypt ... More >> Novartis Investigative Site , Cairo, Egypt Less <<
NCT00439738 Hypertension Phase 4 Completed - United States, Alabama ... More >> Terence T. Hart, MD Muscle Shoals, Alabama, United States, 35662 United States, California Westlake Medical Research Westlake Village, California, United States, 91361 United States, Oklahoma Oklahoma Cardiovascular & Hypertension Oklahoma City, Oklahoma, United States, 73132 United States, Texas Northeast Tarrant Internal Medicine Assoc Euless, Texas, United States, 76040 United States, Washington Frandsen Family Medicine Port Orchard, Washington, United States, 98366 Less <<
NCT00439738 - Completed - -
NCT02403349 Blood Pressure ... More >> Ischemic Stroke Less << Phase 4 Unknown September 2015 -
NCT00425997 Hypertension Phase 4 Completed - United States, New Jersey ... More >> Sites in USA East Hanover, New Jersey, United States, 07936 Less <<
NCT03771729 CKD Early Phase 1 Not yet recruiting June 15, 2019 -
NCT00939588 Hypertension Phase 2 Completed - Russian Federation ... More >> Novartis Investigative Site Moscow, Russian Federation Less <<
NCT00413049 Hypertension Phase 3 Completed - China ... More >> China-Japan Friendship Hospital Beijing, China, 100029 People's hospital affiliated Beijing University Beijing, China, 100044 The third Xiangya hospital of central south University Changsha, China, 410003 The first hospital affiliated the third military Medical University Chongqing, China, 400038 The third hospital affiliated the third military Medical University Chongqing, China, 400042 Union hospital affiliated Fujian medical University Fuzhou, China, 350001 The first hospital affiliated Fujian medical University Fuzhou, China, 350005 The second hospital affiliated Jiangxi medical school Nanchang, China, 330006 Institute of Hypertension, Ruijin Hospital Shanghai, China, 200025 Zhongshan hospital affiliated Fudan University Shanghai, China, 200032 The sixth people's hospital of Shanghai Shanghai, China, 200233 The first hospital affiliated school of medical of Xi'an Jiaotong University Xi'an, China, 710061 Less <<
NCT00413413 Hypertension Phase 3 Completed - China ... More >> Beijing ChaoYang Hospital, Affiliate of Capital University of Medical Sciences Beijing, China, 100020 Beijing General Hospital of Beijing Military Region Beijing, China, 100700 Beijing Hospital Beijing, China, 100730 The First People's Hospital of Hangzhou Hangzhou, China, 310006 The Second Affiliated Hospital of Medical College of Zhejiang University Hangzhou, China, 310006 The First Affiliated Hospital of Medical College of Zhejiang University Hangzhou, China, 310007 Southeast University Affiliated Zhong Da Hospital Nanjing, China, 210009 The First Affiliated Hospital of Nanjing Medical University Nanjing, China, 210029 Second Military Medical University Affiliated Changzheng Hospital Shanghai, China, 200003 Department of cardiology, Ruijin hospital; Shanghai, China, 200025 Department of cardiology, Ruijin hospital Shanghai, China, 200025 Fudan University affiliated zhongshan hospital Shanghai, China, 200032 Second Military Medical University Affiliated Changhai Hospital Shanghai, China, 200433 The First Affiliated Hospital of China Medical University Shenyang, China, 110001 The people's Hospital of Liaoning Province Shenyang, China, 110016 Second Hospital of Hebei University of Medical Sciences Shijiazhuang, China, 050050 The People's Hospital of Hebei Provincial Shijiazhuang, China, 050051 The Second Affiliated Hospital of Soochow University Suzhou, China, 215004 The First Affiliated Hospital of Soochow University Suzhou, China, 215006 Less <<
NCT00413413 - Completed - -
NCT00413049 - Completed - -
NCT00302705 Hypertension Phase 4 Completed - Spain ... More >> Hospital Clínico Universitario de Santiago Santiago de Compostela, Spain, 15706 Less <<
NCT01122251 Essential Hypertension Phase 2 Completed - Korea, Republic of ... More >> 23 sites in Korea Seoul, Busan etc., Korea, Republic of Seoul National University Hospital Seoul, Korea, Republic of Less <<
NCT00394745 Hypertension ... More >>Metabolic Syndrome Less << Phase 3 Completed - Germany ... More >> Investigative Centers, Germany Switzerland Novartis Basel, Switzerland Less <<
NCT01167153 - Completed - -
NCT02900378 Chronic Heart Failure With Red... More >>uced Ejection Fraction Less << Phase 3 Completed - -
NCT01375322 Hypertension ... More >>Diabetes Mellitus, Type 2 Albuminuria Less << Phase 4 Completed - Taiwan ... More >> Chang Gung Memorial Hospital-Kaohsiung Kaohsiung, Taiwan, 833 Taichung Veterans General Hospital Taichung, Taiwan, 407 Tri-Service General Hospital Taipei, Taiwan, 114 Far Eastern Memorial Hospital Taipei, Taiwan, 220 Less <<
NCT01167153 Hypertension Phase 4 Completed - China ... More >> Novartis Pharmaceuticals Beijing, China Less <<
NCT02973035 Hypertension Phase 4 Recruiting June 2019 Korea, Republic of ... More >> Busan Baik Hospital Recruiting Busan, Korea, Republic of Contact: Jeong-Suk Seo, M.D.       orifilter@hanmail.net    Busan University Hospital Recruiting Busan, Korea, Republic of Contact: Yong-Hyun Park       nadroj@chol.com    Chungnam University Hospital Recruiting Daejeon, Korea, Republic of Contact: Jae-Hyung Park, M.D.       jaehpark@cnuh.co.kr    Asan Medical Center Recruiting Seoul, Korea, Republic of Contact: Duk-Hyun Kang, M.D.       dhkang@amc.seoul.kr Less <<
NCT01365481 - Completed - -
NCT01447485 Hypertension ... More >>Chronic Kidney Disease Nephrotic Syndrome Less << Phase 1 Completed - Japan ... More >> Novartis Investigative Site Aichi, Japan Novartis Investigative Site Tokyo, Japan Less <<
NCT01735890 Healthy Phase 1 Completed - -
NCT01365481 Hypertension ... More >>Chronic Kidney Disease Less << Phase 3 Completed - Colombia ... More >> Novartis Investigative Site Bucaramanga, Santander, Colombia, 0001 Novartis Investigative Site Barranquilla, Colombia Novartis Investigative Site Cali, Colombia Finland Novartis Investigative Site Helsinki, Finland, 00029 Germany Novartis Investigative Site Bochum, Germany, 44791 Novartis Investigative Site Cottbus, Germany, 03048 Novartis Investigative Site Freiburg, Germany, 79106 Novartis Investigative Site Homburg, Germany, 66421 Novartis Investigative Site Rostock, Germany, 18107 Guatemala Novartis Investigative Site Guatemala City, Guatemala, 01010 Korea, Republic of Novartis Investigative Site Seoul, Korea, Korea, Republic of, 03080 Philippines Novartis Investigative Site Manila, Philippines, 1000 Novartis Investigative Site Quezon City, Philippines, 1100 Novartis Investigative Site Quezon City, Philippines, 1101 Poland Novartis Investigative Site Warszawa, Poland, 04-154 Romania Novartis Investigative Site Cluj-Napoca, Jud Cluj, Romania Novartis Investigative Site Tg. Mures, jud Mures, Romania, 540104 Novartis Investigative Site Timisoara, jud. Timis, Romania, 300011 Novartis Investigative Site Bucuresti, Romania, 041451 Novartis Investigative Site Bucuresti, Romania, 20395 Novartis Investigative Site Iasi, Romania, 700309 Russian Federation Novartis Investigative Site Kazan, Russian Federation, 420012 Novartis Investigative Site Moscow, Russian Federation, 119991 Novartis Investigative Site Moscow, Russian Federation, 125315 Novartis Investigative Site Moscow, Russian Federation, 127412 Novartis Investigative Site Voronezh, Russian Federation, 394036 Singapore Novartis Investigative Site Singapore, Singapore, 119074 Novartis Investigative Site Singapore, Singapore, 229899 Less <<
NCT00589732 Coronary Artery Disease Phase 4 Completed - Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Samsung Medical Center Seoul, Korea, Republic of St. Mary's Catholic Medical Center Seoul, Korea, Republic of Yonsei University Medical Center Seoul, Korea, Republic of Ajou University Hospital Suwon, Korea, Republic of Less <<
NCT00927394 Hypertension Phase 4 Completed - United States, Delaware ... More >> Investigative Site Newark, Delaware, United States, USA United States, Missouri Investigative Site Kansas, Missouri, United States United States, New Jersey Investigative Site Camden, New Jersey, United States United States, Pennsylvania Investigative Site Philadelphia, Pennsylvania, United States Less <<
NCT00927394 - Completed - -
NCT00415883 Healthy Phase 1 Completed - India ... More >> Novartis Investigative Site Mumbai, India Less <<
NCT01432106 Hypertension ... More >>Metabolic Syndrome Less << Phase 1 Withdrawn(Novartis terminated ... More >>all projects involving aliskiren. Findings of the DMC overseeing the ALTITUDE clinical trial found a higher incidence of adverse events.) Less << - United States, Michigan ... More >> University of Michigan Health System Ann Arbor, Michigan, United States, 48106 Less <<
NCT02554890 Acute Heart Failure Phase 4 Completed - -
NCT00790946 Hypertension ... More >>Obesity Less << Phase 4 Unknown December 2009 Japan ... More >> Chuwa Tei,MD,FACC,FAHA Recruiting Kagoshima, Japan, 890-8520 Contact: Chuwa Tei, MD,FACC,FAHA       tei@m.kufm.kagoshima-u.ac.jp    Contact: Masaaki Miyata, MD,PhD、FACC       miyatam@m3.kufm.kagoshima-u.ac.jp Less <<
NCT01617681 Pediatric Hypertension With or... More >> Without CKD Less << Phase 3 Completed - Belgium ... More >> Novartis Investigative Site Antwerpen, Belgium, 2020 Novartis Investigative Site Liege, Belgium, 4000 Brazil Novartis Investigative Site Curitibia, Parana, Brazil, 80250-060 Novartis Investigative Site Campinas, Brazil, 13087-567 Novartis Investigative Site Caxias do Sul, Brazil, 95070-561 Novartis Investigative Site Porto Alegre, Brazil, 90610-000 France Novartis Investigative Site Montpellier, France, 34059 Germany Novartis Investigative Site Berlin, Germany, 13353 Novartis Investigative Site Marburg, Germany, 35039 Guatemala Novartis Investigative Site Guatemala City, Guatemala, 01010 Novartis Investigative Site Guatemala, Guatemala, 01001 Novartis Investigative Site Guatemala, Guatemala, 1010 Hungary Novartis Investigative Site Budapest, Hungary, H 1096 Novartis Investigative Site Budapest, Hungary, H-1083 Novartis Investigative Site Szeged, Hungary, 6725 Italy Novartis Investigative Site Bologna, BO, Italy, 40138 Novartis Investigative Site San Donato Milanese, MI, Italy, 20097 Novartis Investigative Site Palermo, Italy, 90134 Lithuania Novartis Investigative Site Vinius, Lithuania, 08406 Poland Novartis Investigative Site Bialystok, Poland, 15-274 Novartis Investigative Site Gdansk, Poland, 80-952 Novartis Investigative Site Krakow, Poland, 30-663 Novartis Investigative Site Lodz, Poland, 93-338 Novartis Investigative Site Lublin, Poland, 20-093 Novartis Investigative Site Poznan, Poland, 61-825 Novartis Investigative Site Szczecin, Poland, 71-252 Novartis Investigative Site Warszawa, Poland, 04-154 Less <<
NCT01617681 - Completed - -
NCT00416468 Healthy Phase 1 Completed - United States, New Jersey ... More >> Novartis Investigative Site East Hanover, New Jersey, United States, 07936-1080 Less <<
NCT02343250 Hypertension Phase 1 Completed - -
NCT00416728 Healthy Phase 1 Completed - United States, New Jersey ... More >> Novartis Investigative Site East Hanover, New Jersey, United States, 07936-1080 Less <<
NCT01767259 Healthy Normotensive Participa... More >>nts Less << Not Applicable Completed - Egypt ... More >> Pharmaceutics Department, Faculty of Pharmacy, Damanhour University Damanhour, Egypt Less <<
NCT02788656 Congestive Heart Failure Not Applicable Recruiting March 2019 United States, Massachusetts ... More >> Brigham and Women's Hospita Recruiting Boston, Massachusetts, United States, 02115 Contact: Lynne Stevenson, MD    617-732-5500    lstevenson@partners.org    Contact: Akshay Desai, MD    917-732-5500    adesai@partners.org Less <<
NCT02088008 Healthy Volunteers Phase 1 Unknown - Korea, Republic of ... More >> Seoul National University Hospital Not yet recruiting Seoul, Korea, Republic of Contact: Kyungsang Yu          Principal Investigator: Kyungsang Yu Less <<
NCT01878201 Essential Hypertension Phase 2 Completed - Korea, Republic of ... More >> Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Less <<
NCT02884206 Chronic Heart Failure (CHF) Phase 3 Recruiting May 23, 2022 -
NCT00858299 Chronic Kidney Disease ... More >> Proteinuria Less << Phase 4 Unknown December 2011 Korea, Republic of ... More >> Division of Nephrology, Samsung Medical Center Not yet recruiting Seoul, Korea, Republic of, 135-710 Principal Investigator: Yoon-Goo Kim, Professor Less <<
NCT01918332 Hypertension, ... More >> Hyperlipidemia Less << Phase 3 Completed - Korea, Republic of ... More >> Yonsei University Health System Severance Hospital Seoul, Korea, Republic of Less <<
NCT01241487 Primary Hypertension Phase 4 Completed - Egypt ... More >> Dr Ahmed Anwar Clinic, Cairo, Egypt Less <<
NCT00745953 Metabolic Syndrome ... More >> Lipotoxicity Less << Phase 4 Unknown August 2009 United States, Texas ... More >> University of Texas Southwestern Medical Center Recruiting Dallas, Texas, United States, 75390 Less <<
NCT00457626 Hypertension Phase 3 Completed - -
NCT01918332 - Completed - -
NCT02058446 Essential Hypertension Phase 4 Completed - Taiwan ... More >> Taichung Veterans General Hospital Taichung, Taiwan, 40705 Less <<
NCT03553303 Heart Failure, Systolic Phase 4 Recruiting May 2022 Norway ... More >> Ringerike Hospital Vestre Viken Hospital Trust Recruiting Hønefoss, Buskerud, Norway, 3511 Contact: Christian Hall    +4747500900       Contact: Hall Less <<
NCT00140790 Hypertension Phase 4 Terminated(The number of actua... More >>l events was extremely low. We extended the study period, but it was still not enough. Also, many patients were loss of follow up.) Less << - Japan ... More >> Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University Kumamoto, Japan, 860-8556 Department of Cardiovascular Medicine, Kumamoto University Hospital Kumamoto, Japan, 860-8556 Less <<
NCT01402843 Hypertension ... More >>Dyslipidemia Less << Phase 3 Completed - Korea, Republic of ... More >> Chungbuk National University Hospital Chung Ju, Korea, Republic of Konyang University Hospital Daejeon, Korea, Republic of Asan Medical Center Seoul, Korea, Republic of Gangnam Severance Hospital Seoul, Korea, Republic of Hallym University Medical Center Seoul, Korea, Republic of Korea University Guro Hospital Seoul, Korea, Republic of Samsung Medical Center Seoul, Korea, Republic of Seoul National University Hospital Seoul, Korea, Republic of Severance Hospital Seoul, Korea, Republic of Ajou University Medical Center Suwon, Korea, Republic of Less <<
NCT03476616 Hypertension ... More >>Obesity Less << Phase 4 Not yet recruiting September 1, 2020 Greece ... More >> Hypertension Unit, First Cardiology Clinic, Hippocration General Hospital, University of Athens, Athens, Greece Not yet recruiting Athens, Greece, 11527 Contact: Konstantinos P Tsioufis, Ass. Prof.    6932586087 ext +30    ktsioufis@hippocratio.gr    Contact: Panayiotis P Iliakis, MD    6937489286 ext +30    panayiotisiliakis@gmail.com    Principal Investigator: Konstantinos P Tsioufis, Ass. Prof.          Sub-Investigator: Kyriakos S Dimitriadis, MD, PhD          Sub-Investigator: Panayiotis P Iliakis, MD Less <<
NCT01767298 Healthy Normotensive Participa... More >>nts Less << Not Applicable Completed - -
NCT00208767 Carotid Artery Diseases ... More >> Atherosclerosis Less << Phase 2 Completed - United States, Georgia ... More >> Emory University School of Medicine Atlanta, Georgia, United States, 30322 Less <<
NCT02299310 Chronic Kidney Disease Phase 4 Unknown December 2015 China, Beijing ... More >> Chinese PLA General Hospital Beijing, Beijing, China, 100853 Less <<
NCT02480764 Essential Hypertension Phase 3 Completed - -
NCT03387163 - Recruiting June 17, 2019 United States, New York ... More >> Novartis Investigative Site Recruiting New York, New York, United States, 10029 Less <<
NCT01001572 - Completed - -
NCT01764178 Hyperlipidemia ... More >> Hypertension Less << Phase 1 Completed - Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Less <<
NCT00149227 Hypertension ... More >>Ischemic Heart Disease Congestive Heart Failure Stroke Less << Phase 4 Completed - Japan ... More >> Kyoto Prefectural University of Medicine Kyoto, Japan, 602-8566 Less <<
NCT00149227 - Completed - -
NCT01095822 Diabetes Mellitus Phase 4 Unknown March 2011 United States, Maryland ... More >> Dr. Pokov's Polyclinic. 6821 Reisterstown Road Suite 206 Baltimore, Maryland, United States, 21215 Less <<
NCT00208767 - Completed - -
NCT02662894 Hypertension ... More >>Dyslipidemia Less << Phase 3 Not yet recruiting December 2020 -
NCT02197442 Healthy Not Applicable Completed - India ... More >> Lambda Therapeutic Research Ltd., Ahmedabad, Gujarat, India, 380 061 Less <<
NCT01001572 Essential Hypertension Phase 3 Completed - -
NCT02197494 Healthy Not Applicable Completed - India ... More >> Lambda Therapeutic Research Ltd. Navi Mumbai, Maharashtra, India, 400 614 Less <<
NCT00931710 Stage 2 Systolic Hypertension Phase 4 Completed - United States, New Jersey ... More >> sites in USA East Hanover, New Jersey, United States Less <<
NCT03552575 Heart Failure Phase 3 Not yet recruiting August 31, 2020 -
NCT01920711 Heart Failure With Preserved E... More >>jection Fraction Less << Phase 3 Active, not recruiting May 31, 2019 -
NCT03300427 Heart Failure Phase 4 Recruiting September 2, 2019 Finland ... More >> Novartis Investigative Site Recruiting Turku, Finland Less <<
NCT02817217 Type 2 Diabetes Phase 1 Unknown - China, Sichuan ... More >> People's Liberation Army General Hospital of Chengdu Military Region Recruiting Chengdu, Sichuan, China Contact: Xiaolan Yong, docter    028-86571275    Yongxiaolan@126.com Less <<
NCT01070043 - Completed - -
NCT01070043 Hypertension ... More >>High Blood Pressure Less << Phase 4 Completed - Taiwan ... More >> Taipei, Taiwan, 11217 Less <<
NCT00809926 Stage 2 Hypertension Phase 4 Completed - United States, New Jersey ... More >> Sites in USA East Hanover, New Jersey, United States, 07936 Less <<
NCT02887183 Heart Failure Phase 4 Recruiting October 18, 2018 -
NCT01681576 Salt-sensitive Hypertension Phase 2 Completed - United States, California ... More >> Novartis Investigative Site Anaheim, California, United States, 92801 Novartis Investigative Site Cypress, California, United States, 90630 Novartis Investigative Site Glendale, California, United States, 91206 Hong Kong Novartis Investigative Site Hong Kong, Shatin, NT, Hong Kong Korea, Republic of Novartis Investigative Site Bucheon, Gyeonggi-do, Korea, Republic of, 424-717 Novartis Investigative Site Koyang-si, Gyeonggi-do, Korea, Republic of, 410-773 Novartis Investigative Site Seoul, Korea, Korea, Republic of, 110 744 Novartis Investigative Site Seoul, Korea, Republic of, 120-752 Novartis Investigative Site Seoul, Korea, Republic of, 152-703 Singapore Novartis Investigative Site Singapore, Singapore, 119228 Novartis Investigative Site Singapore, Singapore, 169609 Taiwan Novartis Investigative Site Taipei, Taiwan, ROC, Taiwan, 112 Novartis Investigative Site Taichung, Taiwan, 40447 Novartis Investigative Site Taipei, Taiwan, 10002 Novartis Investigative Site Taipei, Taiwan, 114 Less <<
NCT00809926 - Completed - -
NCT01541189 Hypertension Phase 4 Completed - China, Beijing ... More >> Novartis Investigative Site Beijing, Beijing, China, 100044 Less <<
NCT01681576 - Completed - -
NCT01805804 First Time Dual Chamber Pacema... More >>ker Implantation Less << Phase 4 Recruiting February 2019 Poland ... More >> II Dept. of Cardiology in Zabrze Medical University of Silesia Recruiting Zabrze, Upper Silesia, Poland, 41-800 Principal Investigator: Andrzej R Tomasik, MD PhD FESC          Sub-Investigator: Beata Bialkowska, MD          Sub-Investigator: Wojciech Jachec, MD PhD          Sub-Investigator: Celina Wojciechowska, MD PhD          Sub-Investigator: Damian Kawecki, MD PhD          Sub-Investigator: Katarzyna Wozniak, MD          Sub-Investigator: Grzegorz Banasik, MD Less <<
NCT01425411 Hypertension ... More >>Left Ventricular Hypertrophy Less << Phase 4 Completed - Turkey ... More >> Mustafa Kemal University School of Medicine, Department of Cardiology Antioch, Turkey, 31100 Less <<
NCT01115972 Healthy Pharm... More >>acokinetics of Valsartan Less << Phase 1 Completed - Japan ... More >> Tokyo, Japan Less <<
NCT00657241 Hypertension Phase 3 Completed - United States, New York ... More >> Erie County Medical Center Buffalo, New York, United States, 14215 Less <<
NCT00446524 Hypertension Phase 3 Completed - Japan ... More >> Novartis Investigative Site Fukuoka, Japan Less <<
NCT01850160 Hypertension Phase 3 Completed - Colombia ... More >> Centro de Diagnostico Cardiologico Cartagena, Bolivar, Colombia, 130001 Fundacion Cardiomet Cequin Armenia, Quindio, Colombia, 630001 MedPlus Bogota DC, Colombia, 11001 Ecuador Centro AMCOR Quito, Ecuador, EC170150 Centro Clinico quirurgico Quito, Ecuador, EC170150 Centro médico de hipertensión arterial Quito, Ecuador, EC170150 Clínica DAME Quito, Ecuador, EC170150 Consultorio Edificio Novoa Quito, Ecuador, EC170150 Less <<
NCT02916160 Chronic Heart Failure ... More >> Sleep Apnea Syndrome Less << Not Applicable Recruiting June 22, 2019 France ... More >> Centre Hospitalier Universitaire de Montpellier Recruiting Montpellier, France, 34295 Principal Investigator: François Roubille, MD, PhD          Sub-Investigator: Kamila Solecki, MD          Sub-Investigator: Jean Pierre Mallet, MD          Sub-Investigator: Dany Jaffuel, MD          CHU Nimes Recruiting Nimes, France, 30029 Sub-Investigator: Jean Etienne Ricci, MD          Sub-Investigator: Patrice Ray, MD          Clinique Pasteur Recruiting Toulouse, France, 31000 Principal Investigator: Atul Pathak, MD, PhD Less <<
NCT02518451 Healthy Not Applicable Completed - Indonesia ... More >> PT Equilab International Jakarta, Indonesia, 12430 Less <<
NCT03168568 Heart Failure Phase 4 Recruiting June 30, 2019 Switzerland ... More >> University Heart Center Zurich Recruiting Zurich, Switzerland, 8091 Contact: Frank Ruschitzka, MD    +41442553353    frank.ruschitzka@usz.ch Less <<
NCT00931710 - Completed - -
NCT02631031 Healthy Normotensive Volunteer... More >>s Less << Phase 1 Completed - Egypt ... More >> Ain Shams university Cairo, Egypt, 11566 Less <<
NCT02815657 Type 2 Diabetes Phase 1 Completed - China ... More >> People's Liberation Army General Hospital of Chengdu Military Region Chengdu, China Less <<
NCT03535376 - Recruiting October 2026 Norway ... More >> St. Olavs University Hospital Recruiting Trondheim, Norway Contact: Magnus Strømmen, MSc Less <<
NCT03594825 Hypertension;Nephropathy Phase 4 Not yet recruiting December 2023 -
NCT01912534 Hypertrophic Cardiomyopathy Phase 2 Active, not recruiting July 2019 United States, California ... More >> Stanford University Stanford, California, United States, 94305 United States, Colorado University of Colorado Aurora, Colorado, United States, 80045 United States, Illinois University of Chicago Chicago, Illinois, United States, 60637 United States, Maryland Johns Hopkins University Baltimore, Maryland, United States, 21287 United States, Massachusetts Brigham & Women's Hospital Boston, Massachusetts, United States, 02115 Children's Hospital Boston Boston, Massachusetts, United States, 02115 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109 United States, Missouri Washington University School Medicine Saint Louis, Missouri, United States, 63110 United States, Ohio Cinncinnati Children's Hospital Medical Center Cincinnati, Ohio, United States, 45229 Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee Vanderbilt University Nashville, Tennessee, United States, 37232 Canada, Ontario Toronto General Hospital Toronto, Ontario, Canada, M4W3S5 Toronto Sick Kids Toronto, Ontario, Canada, M5G1X8 Less <<
NCT02690974 Hearth Failure With Reduced Ej... More >>ection Fraction (HFrEF) Less << Phase 4 Completed - Canada, Alberta ... More >> Novartis Investigative Site Edmonton, Alberta, Canada, T5H 3V9 Canada, British Columbia Novartis Investigative Site New Westminster, British Columbia, Canada, V3L 3W4 Novartis Investigative Site Vancouver, British Columbia, Canada, V6Z 1Y6 Canada, Manitoba Novartis Investigative Site Winnipeg, Manitoba, Canada, R2H 2A6 Canada, New Brunswick Novartis Investigative Site Moncton, New Brunswick, Canada, E1C 2Z3 Novartis Investigative Site Moncton, New Brunswick, Canada, E1G 1A7 Canada, Newfoundland and Labrador Novartis Investigative Site St. John's, Newfoundland and Labrador, Canada, A1B 3V6 Canada, Ontario Novartis Investigative Site Burlington, Ontario, Canada, L7M 4Y1 Novartis Investigative Site Cambridge, Ontario, Canada, N1R 6V6 Novartis Investigative Site London, Ontario, Canada, N6A 5A5 Novartis Investigative Site Mississauga, Ontario, Canada, L5K 2L3 Novartis Investigative Site Newmarket, Ontario, Canada, L3Y 2P6 Novartis Investigative Site Newmarket, Ontario, Canada, L3Y 8C3 Novartis Investigative Site Ottawa, Ontario, Canada, K1Y 4W7 Novartis Investigative Site Peterborough, Ontario, Canada, K9J 0B2 Novartis Investigative Site Sarnia, Ontario, Canada, N7T 4X3 Novartis Investigative Site Scarborough, Ontario, Canada, M1E 5E9 Novartis Investigative Site Scarborough, Ontario, Canada, M1P 2V5 Novartis Investigative Site Sudbury, Ontario, Canada, P3E 3B8 Novartis Investigative Site Sudbury, Ontario, Canada, P3E 5M9 Novartis Investigative Site Toronto, Ontario, Canada, M6R 1B5 Novartis Investigative Site Waterloo, Ontario, Canada, N2T 0C1 Novartis Investigative Site Weston, Ontario, Canada, M9N 1W4 Canada, Quebec Novartis Investigative Site Greenfield Park, Quebec, Canada, J4V 2G8 Novartis Investigative Site Joliette, Quebec, Canada, J6E 6J2 Novartis Investigative Site Montreal, Quebec, Canada, H1T 3Y7 Novartis Investigative Site St-Jean-sur-Richelieu, Quebec, Canada, J3A 1J2 Novartis Investigative Site Terrebonne, Quebec, Canada, J6V 2H2 Canada Novartis Investigative Site Brossard, Canada, J4Z 2K9 Novartis Investigative Site Hamilton, Canada, L8L 0A9 Novartis Investigative Site Quebec, Canada, GIV 4G5 Novartis Investigative Site St-Lambert, Canada, J4P 2J2 Less <<
NCT03180593 Hypertension Complicated ... More >> Hypertrophy, Left Ventricular Blood Pressure Less << Phase 4 Completed - United States, Texas ... More >> Trinity Hypertension & Metabolic Research Institute Carrollton, Texas, United States, 75006 Less <<
NCT01918709 Hypertension, Hyperlipidemia Phase 1 Completed - Korea, Republic of ... More >> Clinical Trial Center, Samsung Medical Center Seoul, Korea, Republic of Less <<
NCT03371797 - Completed - Pakistan ... More >> Medicell Karachi, Sindh, Pakistan, 75290 Less <<
NCT02130687 Type 2 Diabetes Mellitus ... More >> Hypertension Less << Not Applicable Recruiting June 2020 United States, Tennessee ... More >> Vanderbilt University Recruiting Nashville, Tennessee, United States, 37232 Contact: Jessica R Wilson, M.D.       jessica.r.wilson@vanderbilt.edu    Contact: Scott Hubers, M.D.       scott.hubers@vanderbilt.edu    Principal Investigator: Nancy J Brown, M.D.          Sub-Investigator: Jessica Devin, M.D.          Sub-Investigator: Jessica R Wilson, M.D.          Sub-Investigator: Claudia E Ramirez, M.D.          Sub-Investigator: Scott Hubers, M.D. Less <<
NCT01245608 Cardiovascular Diseases Phase 3 Active, not recruiting September 2018 Iran, Islamic Republic of ... More >> Golestan Cohort Center Gonbad, Golestan, Iran, Islamic Republic of Less <<
NCT00457483 Primary Hypertension Phase 4 Completed - Netherlands ... More >> Nijmegen monitoring project coordinated from Nijmegen Nijmegen, Netherlands Less <<
NCT00309257 Alport Syndrome Phase 2 Completed - Italy ... More >> Clinical Research Center for Rare Diseases Ranica, Bergamo, Italy, 24020 Less <<
NCT03639493 Healthy Male Subjects Phase 1 Completed - Korea, Republic of ... More >> Korea University Anam Hospital Seoul, Korea, Republic of Less <<
NCT02787798 Heart Failure Phase 4 Recruiting May 2019 France ... More >> CHU de Toulouse Recruiting Toulouse, France Contact: Michel Galinier, MD       galinier.m@chu-toulouse.fr Less <<
NCT01823913 Healthy Phase 1 Completed - Korea, Republic of ... More >> Severance Hospital Seoul, Korea, Republic of, 120-752 Less <<
NCT00407680 Type 2 Diabetes Mellitus ... More >> Hypertension Less << Phase 4 Unknown March 2009 Japan ... More >> Kitasato University Recruiting 1-15-1 Kitasato Sagamihara, Kanagawa, Japan, 228-8111 Contact: Keiji Tanaka    +81-427-8111 ext 8706    keiji@med.kitasato-u.ac.jp    Principal Investigator: Keiji Tanaka, Keiji Tanaka Less <<
NCT00530595 Cardiovascular Disease Not Applicable Completed - -
NCT02824081 Major Depressive Episode ... More >> Suicidal Behavior Less << Not Applicable Unknown November 2017 France ... More >> University Hospital Recruiting Montpellier, France, 34295 Contact: Catherine GENTY, MD    +33 4 67 99 61 45 75    c-genty@chu-montpellier.fr Less <<
NCT00154271 Hypertension Phase 4 Completed - -
NCT02639637 Type 2 Diabetes Mellitus Phase 4 Completed - United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less <<
NCT02639637 - Completed - -
NCT00130156 High Blood Pressure Phase 4 Completed - Taiwan ... More >> National Taiwan University Hospital. Taipei, Taiwan Less <<
NCT03738878 Hypertension Phase 4 Recruiting December 31, 2020 United States, Tennessee ... More >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37205 Contact: Nancy J Brown, MD    615-343-8701       Contact: Dustin Mayfield, RN    615-343-8701 Less <<
NCT02924727 Acute Myocardial Infarction Phase 3 Recruiting April 27, 2020 -
NCT01652339 Healthy Male Subjects Phase 1 Completed - Korea, Republic of ... More >> Inje University Busan Paik Hospital Busan, Korea, Republic of, 614-735 Less <<
NCT01692301 - Completed - -
NCT02174328 Pre-Eclampsia Phase 3 Suspended(Halted prematurely d... More >>ue to low recruitment rate.) Less << May 31, 2018 Spain ... More >> Obstetrics Unit of La Fe University and Politechnic Hospital Valencia, Spain, 46026 Less <<
NCT03757390 Healthy Subjects Phase 1 Recruiting December 14, 2018 Korea, Republic of ... More >> Korea University Anam Hospital Recruiting Seoul, Korea, Republic of Less <<
NCT03541109 Ischemic Heart Disease ... More >> Acute Coronary Syndrome Revascularization Less << Phase 3 Not yet recruiting August 2023 Iran, Islamic Republic of ... More >> Cardiovascular Research Institute Not yet recruiting Isfahan, Iran, Islamic Republic of Contact: Safoora yazdekhasti    00983136115208    sfa.yazdekhasti@gmail.com    Sub-Investigator: Nizal Sarrafzadegan, Professor          Sub-Investigator: Shervin Gh Hoseini, MD, PhD          Sub-Investigator: Hamidreza Roohafza, MD          Sub-Investigator: Marjan Mansourian, PhD          Sub-Investigator: Jamshid Najafian, MD          Sub-Investigator: Alireza Nateghi Nateghi, PhD Less <<
NCT01692301 Hypertension Phase 2 Completed - -
NCT03066804 Heart Failure With Preserved E... More >>jection Fraction Less << Phase 3 Recruiting December 4, 2019 -
NCT01318395 Arterial Hypertension Phase 3 Completed - Germany ... More >> Clinical Research Unit, Department of Nephrology and Hypertension, University of Erlangen-Nürnberg Erlangen, Germany, 91054 Clinical Research Unit, Department of Nephrology and Hypertension, University of Erlangen-Nürnberg Nürnberg, Germany, 90471 Less <<
NCT00738972 Hypertension Phase 3 Terminated(Study terminated ea... More >>rly due to sample size, not possible to perform further statistical analysis.) Less << - -
NCT00738972 - Terminated(Study terminated ea... More >>rly due to sample size, not possible to perform further statistical analysis.) Less << - -
NCT01252238 - Terminated(Study sponsor termi... More >>nated study due to AE's reported with valsartan and aliskiren) Less << - -
NCT01917149 Dilated Cardiomyopathy Phase 4 Completed - China ... More >> Xijing Hospital, Department of Cardiology Xi'an, China, 710032 Less <<
NCT01353508 Hypertension Phase 2 Completed - Russian Federation ... More >> Novartis Investigative Site Moscow, Russian Federation, 117198 Less <<
NCT00878969 Oxidative Stress ... More >> Endothelial Dysfunction Less << Phase 3 Terminated(insufficient enroll... More >>ment and retention) Less << - United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less <<
NCT00171444 Hypertension Phase 4 Completed - -
NCT01252238 Insulin Sensitivity ... More >> Aortic Compliance Diastolic Function Less << Not Applicable Terminated(Study sponsor termi... More >>nated study due to AE's reported with valsartan and aliskiren) Less << - United States, Massachusetts ... More >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Less <<
NCT01353508 - Completed - -
NCT00878969 - Terminated(insufficient enroll... More >>ment and retention) Less << - -
NCT03657472 Hypertension ... More >>Hyperlipidemia Less << Phase 1 Completed - Korea, Republic of ... More >> Samsung Medical Center Seoul, Korea, Republic of, 135-710 Less <<
NCT01030458 Blood Pressure Phase 4 Completed - Cameroon ... More >> Ecole de Médecine de Douala Douala, Cameroon Hôpital Général de Yaoundé Yaoundé, Cameroon, BP 5408 Côte D'Ivoire Institut de Cardiologie d'Abidjan Abidjan, Côte D'Ivoire, BP V 206 Gabon Hôpital Central Universitaire de Libreville Libreville, Gabon, BP 4908 Nigeria University of Enugu Enugu, Nigeria University of Ilorin Ilorin, Nigeria, PMB 1515 Senegal Hôpital Aristide Le Dantec Dakar, Senegal Less <<
NCT03009474 Hypertension ... More >>Hyperlipidemias Less << Phase 1 Completed - Korea, Republic of ... More >> Korea University Anam Hospital Seoul, Korea, Republic of Less <<
NCT02572960 Osteoporosis ... More >>Vitamin D Deficiency Cardiovascular Disease Less << Phase 4 Completed - Denmark ... More >> Department of Endocrinology and Internal Medicine Aarhus, Denmark, 8000 Less <<
NCT01030458 - Completed - -
NCT01819779 Healthy Male Subjects Phase 1 Completed - Korea, Republic of ... More >> Metro Hospital Anyang, Kyung Gi, Korea, Republic of, 430-720 Less <<
NCT03336099 Osteoarthritis, Knee ... More >> Pain Less << Not Applicable Completed - France ... More >> Thermes de Vals Les Bains Vals Les Bains, Ardèche, France, 07600 Less <<
NCT00494715 Diabetes Phase 3 Completed - Italy ... More >> Clinical Research Center for Rare Diseases "Aldo e Cele Daccò" Ranica, Bergamo, Italy Hospital "Bolognini" Seriate, Bergamo, Italy Hospital "S.Marta e S.Venera" Acireale, Catania, Italy Hospital " Casa Sollievo della Sofferenza" - Unit of Nephrology San Giovanni Rotondo, Foggia, Italy Hospital "Azienda Ospedaliera Ospedali Riuniti di Bergamo" - Unit of Diabetology Bergamo, Italy Hospital "Vittorio Emanuele-Ferrarotto-Santo Bambino" Catania, Italy IRCCS San Raffaele - Unit of General Medicine Milan, Italy University "Federico II" Napoli, Italy Hospital "Azienda Ospedaliera di Parma" - Unit of Nephrology Parma, Italy Hospital "Azienda Ospedaliera di Treviglio e Caravaggio" - Ambulatory of Ponte San Pietro Ponte San Pietro, Italy Hospital "Azienda Ospedaliera di Treviglio e Caravaggio" Unit of Diabetology and Metabolic Diseases Romano di Lombardia, Italy University - AUSL 1 - Institute of Medical Pathology Sassari, Italy Hospital "G:Mazzini" Teramo, Italy Hospital "Azienda Ospedaliera di Treviglio-Caravaggio"Unit of Diabetology and Metabolic Diseases Treviglio, Italy Slovenia Clinical Department of Endocrinology, Diabetes and Metabolic Diseases University Medical Centre Ljubljana Ljubljana, Slovenia, 1000 Less <<
NCT00732069 End Stage Renal Failure on Dia... More >>lysis Complication of Hemodialysis Less << Phase 2 Completed - United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37323 Less <<
NCT00732069 - Completed - -
NCT00367562 IGA Nephropathy Phase 4 Completed - Argentina ... More >> Hospital Britanico de Buenos Aires Buenos Aires, Argentina, 1280 Less <<
NCT03532854 Healthy Male Volunteers Phase 1 Not yet recruiting September 18, 2018 Korea, Republic of ... More >> LG chem Not yet recruiting Seoul, Gangseo-Gu, Korea, Republic of, 07795 Contact: Subin Lee    02-6987-4153    leesubin@lgchem.com Less <<
NCT00239538 Hypertension ... More >>Diabetes Mellitus, Type 2 Less << Phase 4 Completed - -
NCT00921570 Diabetes Hype... More >>rtension Proteinuria Less << Phase 4 Completed - Turkey ... More >> GATA Nephrology Ankara, Turkey, 06108 Less <<
NCT01904981 Small Abdominal Aortic Aneurys... More >>m Less << Phase 4 Unknown October 2016 Korea, Republic of ... More >> Severance Hospital Recruiting Seoul, Korea, Republic of, 120-752 Contact: Dong-Hoon Choi, MD    82 2 2228 8449    cdhlyj@yuhs.ac Less <<
NCT02060019 Healthy Phase 1 Completed - Korea, Republic of ... More >> Kyungpook university hospital Deagu, Korea, Republic of Less <<
NCT02058823 Hypoxia Sleep... More >> Apnea Obstructive Sleep Apnea Less << Phase 4 Unknown December 2017 France ... More >> Laboratoire EFCR - Functional Cardio-respiratory Exploration Laboratory La Tronche, Isère, France, 38700 Less <<
NCT01672476 Hypertension Phase 3 Completed - Korea, Republic of ... More >> Severance Hospital Seoul, Korea, Republic of Less <<
NCT03508739 Diabetes Mellitus, Type 2 ... More >> Pre-diabetic Hypertension Elevated Blood Pressure Less << Phase 3 Recruiting June 30, 2020 United States, Pennsylvania ... More >> University of Pennsylvania Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Jessica R Wilson, MD, MSCI Less <<
NCT00821574 Hypertension, Dyslypidaemia Phase 4 Completed - -
NCT01699490 Major Depressive Disorder Phase 4 Unknown July 2015 Taiwan ... More >> Department of Psychiatry, National Cheng-Kung University Hospital Recruiting Tainan, Taiwan, 701 Contact: Po See Chen, M.D., Ph.D.    +886-6-2353535 ext 5213    chenps@mail.ncku.edu.tw Less <<
NCT01518855 Hypertension Phase 4 Completed - Japan ... More >> Sapporo, Hokkaido, Japan, 060-0003 Setagaya-ku, Tokyo, Japan, 158-0097 Shinjuku-ku, Tokyo, Japan, 163-6003 Hiroshima, Japan, 733-0011 Less <<
NCT00338936 Hypertension Phase 3 Completed - -
NCT03432468 Hypertension Not Applicable Not yet recruiting August 1, 2019 -
NCT00202618 Hypertension ... More >>Diabetes Mellitus Albuminuria Less << Phase 4 Unknown - Japan ... More >> Shiga University of Medical Science Recruiting Otsu, Shiga, Japan, 520-2192 Contact: Atsunori Kashiwagi, Professor    81-77-548-2221    kasiwagi@belle.shiga-med.ac.jp    Contact: Hiroshi Maegawa, A. Professor    81-77-548-2222    maegawa@belle.shiga-med.ac.jp    Principal Investigator: Hiroshi Maegawa          Principal Investigator: Yasuo Kida          Principal Investigator: Shu Yamada          Principal Investigator: Masataka Nishimura          Principal Investigator: Tetsuro Arimura          Principal Investigator: Noriko Takahara          Principal Investigator: Katsuya Egawa          Principal Investigator: Masanori Iwanishi          Principal Investigator: Toshiki Fujita          Principal Investigator: Aya Kadota Less <<
NCT03648333 Healthy Male Subjects Phase 1 Completed - -
NCT02765594 Primary IgA Nephropathy Phase 4 Recruiting June 2019 China ... More >> Peing Union Medical College Hospital Recruiting Beijing, China, 100730 Contact: Ruitong Gao, MD    86-010-69155058    gaoruitong@gmail.com Less <<
NCT00219180 Hypertension Phase 3 Completed - United States, New Jersey ... More >> Novartis Pharmaceuticals East Hanover, New Jersey, United States, 07936 Germany Investigative Centers, Germany Less <<
NCT02433119 Hypertension Phase 4 Completed - Korea, Republic of ... More >> Gachon University Gil Hospital Incheon, Korea, Republic of Less <<
NCT00409487 Hypertension, ... More >> Obstructive Sleep Apnea Less << Phase 4 Completed - France ... More >> University Hospital Grenoble Grenoble, France, 38000 Less <<
NCT00219102 Hypertension ... More >>Diabetes Less << Phase 3 Completed - United States, North Carolina ... More >> Investigative Site Salisbury,, North Carolina, United States, 28144 Belgium Investigative Site Kortrijk, Belgium Romania Investigative Site Bucharest, Romania Spain Investigative Site Madrid, Spain Sweden Investigative Site Stockholm, Sweden Switzerland Novartis Pharmaceuticals Basel, Switzerland Ukraine Investigative Site Kiev, Ukraine Less <<
NCT00089518 HIV Infections ... More >> Kidney Disease Less << Phase 3 Withdrawn - United States, Indiana ... More >> Indiana University Hospital Indianapolis, Indiana, United States, 46202-5250 Methodist Hospital of Indiana Indianapolis, Indiana, United States, 46202-5250 Wishard Hospital Indianapolis, Indiana, United States, 46202 United States, Missouri Washington University (St. Louis) St. Louis, Missouri, United States, 63108-2138 United States, New York NYU/Bellevue New York, New York, United States, 10016-6481 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Ohio MetroHealth Medical Center Cleveland, Ohio, United States, 44109-1998 United States, Rhode Island Rhode Island Hospital Providence, Rhode Island, United States, 02906 Stanley Street Treatment and Resource Providence, Rhode Island, United States, 02906 The Miriam Hospital Providence, Rhode Island, United States, 02906 Less <<
NCT00721773 Renal Function Disorder Not Applicable Completed - China, Guangdong ... More >> The 1st Affiliated Hospital, Sun Yet-sen University GuangZhou, Guangdong, China, 510080 Less <<
NCT00311740 Hypertension Phase 3 Completed - Japan ... More >> Novartis Pharmaceuticals Tokyo, Japan Less <<
NCT00627991 Cerebrovascular Accident Not Applicable Withdrawn - United States, California ... More >> Stanford University School of Medicine Stanford, California, United States, 94305 Less <<
NCT00922441 Essential Hypertension Phase 2 Completed - -
NCT03415906 Heart Failure Phase 2 Withdrawn(Difficulties in recr... More >>uiting patients) Less << - Germany ... More >> Clinical Research Center Hannover, Hannover Medical School Hannover, Germany, 30625 Less <<
NCT00922441 - Completed - -
NCT03536598 Hypertension With Hyperlipidem... More >>ia Less << Phase 3 Completed - -
NCT00732966 Hypertension Not Applicable Unknown - -
NCT02636283 Peripheral Arterial Disease Phase 2 Recruiting July 2019 United States, Minnesota ... More >> University of Minnesota Medical Center Recruiting Minneapolis, Minnesota, United States, 55455 Less <<
NCT00168779 Hypertension Phase 4 Completed - -
NCT00240448 Hypertension Phase 4 Completed - -
NCT02687932 Mitral Valve Insufficiency ... More >> Left Ventricular Dysfunction Less << Phase 4 Completed - Korea, Republic of ... More >> Inha University Hospital Incheon, Korea, Republic of Asan Medical Center Seoul, Korea, Republic of, 138-736 Samsung Medical Center Seoul, Korea, Republic of Yonsei University Medical Center Seoul, Korea, Republic of Less <<
NCT00549770 Hypertension Phase 2 Completed - -
NCT00394823 Hypertension Phase 3 Completed - Germany ... More >> Investigative Centers, Germany Switzerland Novartis Basel, Switzerland Less <<
NCT00500604 Hypertension Phase 4 Completed - Egypt ... More >> Sanofi-Aventis Administrative Office Cairo, Egypt Hong Kong Sanofi-Aventis Administrative Office Hong Kong, Hong Kong India Sanofi-Aventis Administrative Office Mumbai, India Indonesia Sanofi-Aventis Administrative Office Jakarta, Indonesia Korea, Republic of Sanofi-Aventis Administrative Office Seoul, Korea, Republic of Malaysia Sanofi-Aventis Administrative Office Kuala Lumpur, Malaysia Morocco Sanofi-Aventis Administrative Office Casablanca, Morocco Pakistan Sanofi-Aventis Administrative Office Karachi, Pakistan Philippines Sanofi-Aventis Administrative Office Makati City, Philippines Singapore Sanofi-Aventis Administrative Office Singapore, Singapore Taiwan Sanofi-Aventis Administrative Office Taipei, Taiwan Thailand Sanofi-Aventis Administrative Office Bangkok, Thailand Tunisia Sanofi-Aventis Administrative Office Megrine, Tunisia Vietnam Sanofi-Aventis Administrative Office Ho Chi Minh City, Vietnam Less <<
NCT00549770 - Completed - -
NCT00503152 Diabetes Phase 3 Completed - Italy ... More >> Hospital "Azienda Ospedaliera di Treviglio e Caravaggio" - Diabetologic Ambulatory of Ponte San Pietro Ponte San Pietro, Bergamo, Italy Clinical Research Center for Rare Diseases "Aldo e Cele Daccò" Ranica, Bergamo, Italy Hospital "Azienda Ospedaliera di Treviglio e Caravaggio" Unit of Diabetology and Metabolic Diseases Romano di Lombardia, Bergamo, Italy Hospital "Bolognini" Seriate, Bergamo, Italy Hospital "Azienda Ospedaliera di Treviglio-Caravaggio"Unit of Diabetology and Metabolic Diseases Treviglio, Bergamo, Italy Hospital "Casa Sollievo della Sofferenza" - Division of Endocrinology San Giovanni Rotondo, Foggia, Italy Hospital "Azienda Ospedaliera Ospedali Riuniti di Bergamo" - Unit of Diabetology Bergamo, Italy IRCCS San Raffaele - Unit of General Medicine Milano, Italy Azienda USL 2 Olbia, Italy Less <<
NCT00351130 Hypertension Phase 4 Completed - Germany ... More >> Investigative Centers, Germany Switzerland Novartis Pharmaceuticals Basel, Switzerland Less <<
NCT03553810 Hypertensive Heart Disease Phase 3 Not yet recruiting December 31, 2021 Singapore ... More >> National Heart Centre Singapore Not yet recruiting Singapore, Singapore, 169609 Contact: Calvin WL Chin, MD, PhD          Principal Investigator: Calvin WL Chin, MD, PhD Less <<
NCT02495324 Essential,Hypertension Phase 4 Completed - Korea, Republic of ... More >> The Catholic University of Korea, Seoul St.Mary's Hospital Seoul, Banpo-dong, Seocho-gu, Korea, Republic of, 137-701 The Catholic University of Korea, Incheon St.Mary's Hospital Incheon, Bupyeong-gu, Korea, Republic of, 403-720 The Catholic University of Korea, St. Paul's Hospital Seoul, Dongdaemun-gu, Korea, Republic of, 130-709 The Catholic University of Korea, St.Vincent's Hospital. Suwon-si, Gyeonggi-do, Korea, Republic of, 442-723 The Catholic University of Korea,Uijeongbu St.Mary's Hospital Uijeongbu, Gyeonggi-do, Korea, Republic of, 480-717 The Catholic University of Korea, Daejeon St. Mary's Hospital Daejeon, Jung-gu/Daeheung-ro, Korea, Republic of, 301-723 The Catholic University of Korea, Bucheon St.Mary's Hospital Bucheon, Kyunggi-Do, Korea, Republic of, 420-717 The Catholic University of Korea,Yeouido St.Mary's Hospital Seoul, Yeongdeungpo-gu, Korea, Republic of, 150-713 Less <<
NCT00171782 HYPERTENSION Phase 4 Completed - -
NCT00171132 Hypertension Phase 4 Completed - Germany ... More >> Investigative Centers, Germany Switzerland Novartis Pharmaceuticals Basel, Switzerland Less <<
NCT00129233 Hypertension ... More >>Type 2 Diabetes Mellitus Less << Phase 4 Completed - Japan ... More >> Department of Cardiology, Nagoya University Graduate School of Medicine Nagoya, Aichi, Japan, 466-8550 Less <<
NCT01071122 Hypertension Phase 4 Completed - Korea, Republic of ... More >> Goyang-si, Gyeonggido, Korea, Republic of, 411-706 Goyang, Gyeonggido, Korea, Republic of, 410-773 Chungchungbuk-do, Korea, Korea, Republic of, 361-711 Seoul, Korea, Korea, Republic of, 135-720 Seoul, Seoul Teugbyeolsi, Korea, Republic of, 152-703 Busan, Korea, Republic of Gwangju, Korea, Republic of, 501-757 Joong-gu, Korea, Republic of, 100-380 Kungki-do, Korea, Republic of, 463-707 Seoul, Korea, Republic of, 110-744 Seoul, Korea, Republic of, 120-752 Seoul, Korea, Republic of, 135-710 Seoul, Korea, Republic of, 136-705 Seoul, Korea, Republic of, 137-701 Suwan, Korea, Republic of, 443-721 Less <<
NCT00219193 Hypertension Phase 3 Completed - United States, New Jersey ... More >> Novartis Pharmaceuticals East Hanover, New Jersey, United States, 07936 Germany Investigative Centers, Germany Less <<
NCT00151229 Aged Systolic... More >> Hypertension Less << Phase 4 Completed - Japan ... More >> VALISH Data Center ING Corporation, 8-21, Shinjuku-ku, Tokyo, Japan, 162-0067 Less <<
NCT03639480 Hypertension ... More >>Hyperlipidemia Less << Phase 3 Enrolling by invitation October 2018 Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of Less <<
NCT00250562 Hypertension Phase 3 Completed - United States, New Jersey ... More >> Novartis Pharmaceuticals East Hanover, New Jersey, United States, 07936 Less <<
NCT00185055 Healthy Phase 4 Completed - -
NCT02606279 HIV Aging ... More >> Sarcopenia Angiotensin Receptor Antagonists Less << Not Applicable Terminated(Change in study des... More >>ign and inability to recruit participants) Less << - United States, North Carolina ... More >> Wake Forest University Health Sciences Winston-Salem, North Carolina, United States, 27157 Less <<
NCT02606279 - Terminated(Change in study des... More >>ign and inability to recruit participants) Less << - -
NCT00171535 Hypertension Phase 3 Completed - United States, New Jersey ... More >> Novartis Pharmaceuticals East Hanover, New Jersey, United States, 07936 Less <<
NCT00170989 Hypertension Phase 3 Completed - Germany ... More >> Investigative Centers, Germany Switzerland Novartis Pharmaceuticals Basel, Switzerland Less <<
NCT00327587 Hypertension Phase 3 Completed - United States, New Jersey ... More >> Novartis Pharmaceuticals Corporation E. Hanover, New Jersey, United States, 07936 Less <<
NCT01400256 Stroke, Acute Phase 4 Withdrawn(lack of recruitment/... More >>patient population) Less << - United States, California ... More >> Stanford University Medical Center Stanford, California, United States, 94304 Less <<
NCT01819220 Hypertension Phase 4 Completed - Korea, Republic of ... More >> Yonsei universty medical center Seoul, Korea, Republic of, 120-752 Less <<
NCT00241150 Hypertension ... More >>Metabolic Syndrome Less << Phase 4 Completed - -
NCT00308425 De Novo Renal Transplantation Phase 3 Completed - -
NCT01508026 Stage 1 Hypertension ... More >> Stage 2 Hypertension Less << Phase 3 Completed - -
NCT01281306 Systolic Hypertension Phase 2 Completed - -
NCT00696436 Hypertension Phase 3 Completed - -
NCT01281306 - Completed - -
NCT00518219 Membranous Nephropathy Phase 4 Completed - China, Jiangsu ... More >> Research Institute of Nephrology Nanjing, Jiangsu, China, 210002 Less <<
NCT03012763 Pharmacokinetics ... More >> Magnetic Resonance Imaging Administration, Oral Less << Phase 1 Completed - -
NCT02874794 Heart Failure and Reduced Ejec... More >>tion Fraction Less << Phase 4 Recruiting March 7, 2019 -
NCT00327145 Hypertension Phase 3 Completed - Switzerland ... More >> Novartis Pharmaceuticals Basel, Switzerland Less <<
NCT00696436 - Completed - -
NCT02996552 Tricuspid Disease ... More >> Mitral Regurgitation Less << Not Applicable Recruiting June 2021 Italy ... More >> Istituto Clinico Humanitas Recruiting Rozzano, Milano, Italy, 20089 Contact: Lucia Torracca, MD    00390282244330    lucia.torracca@humanitas.it    Principal Investigator: Lucia Torracca, MD          Sub-Investigator: Andrea Fumero, MD          IRCCS Ospedale San Raffaele Recruiting Milan, Italy, 20132 Contact: Michele De Bonis, MD    00390226437118    debonis.michele@hsr.it    Principal Investigator: Michele De Bonis, MD,FESC,FAHA          Sub-Investigator: Cinzia Trumello, MD          Sub-Investigator: Teodora Nisi, MD          Sub-Investigator: Elisabetta Lapenna, MD          Sub-Investigator: Ottavio Alfieri, MD          Poland Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland Recruiting Warsaw, Poland, 02-507 Contact: Piotr Suwalski, MD    0048225081260    suwalski.piotr@gmail.com    Principal Investigator: Piotr Suwalski, MD Less <<
NCT02923921 Pancreatic Cancer Phase 3 Recruiting March 31, 2020 -
NCT00399269 Anemia Phase 3 Completed - India ... More >> Dr. Shishir Gang Nadiad, Gujarat, India Less <<
NCT00297973 Hypertension Phase 4 Completed - -
NCT00804167 - Completed - -
NCT01078688 - Completed - -
NCT01258114 Overweight Ob... More >>esity Less << Phase 3 Completed - France ... More >> Cabinet Médical Brides les bains, France, 73000 Cabinet Medical Capvern les bains, France, 65000 Cabinet Medical Vals les bains, France, 07000 Cabinet Medical Vichy, France, 03000 Cabinet Medical Vittel, France, 88000 Less <<
NCT02694796 Physical Activity ... More >> Chronic Diseases Obesity Diabetes Rheumatic Diseases Cardiovascular Diseases Breast Cancer Chronic Obstructive Pulmonary Disease Less << Not Applicable Completed - France ... More >> Thermes CHEVALLEY Aix-les-Bains, France, 73100 Centre thermal d'Amélie-les-Bains Amélie-les-Bains, France, 66110 Thermes de Bourbon-Lancy Bourbon Lancy, France, 71140 Thermes de Brides-les-Bains Brides-les-Bains, France, 73573 Caleden Complexe Thermal Chaudes-Aigues, France, 15110 Centre thermal d'Eugénie-les-Bains Eugénie-les-Bains, France, 40320 Thermes du Boulou Le Boulou, France, 66160 Thermes de Vals-les-Bains Vals-les-Bains, France, 07600 Thermes CALLOU Vichy, France, 03200 Less <<
NCT01055353 - Completed - -
NCT00753636 - Completed - -
NCT01368536 Hypertension ... More >>Stage 2 Hypertension Diabetes Less << Phase 4 Terminated(Based on results fr... More >>om an ALTITUDE study interim analysis, testing aliskiren concomitantly with an ACE inhibitor or ARB, in diabetics with renal impairment) Less << - -
NCT00753636 Parkinson's Disease Phase 2 Completed - United States, Illinois ... More >> 710 N. Lake Shore Dr. Chicago, Illinois, United States, 60610 Less <<
NCT00833573 - Completed - -
NCT02200822 Heart Failure (HF) Phase 4 Unknown July 2017 Belgium ... More >> Ziekenhuis Oost Limburg Recruiting Genk, Limburg, Belgium, 3600 Contact: Petra Nijst, MD    3289761525    nijst.petra@gmail.com    Contact: Wilfried Mullens, MD, PhD    3289327110    wilfried.mullens@zol.Be    Principal Investigator: Petra Nijst, MD          Principal Investigator: Frederik Verbrugge, MD          Principal Investigator: Matthias Dupont, MD          Principal Investigator: Wilfried Mullens, MD, PhD Less <<
NCT01368536 - Terminated(Based on results fr... More >>om an ALTITUDE study interim analysis, testing aliskiren concomitantly with an ACE inhibitor or ARB, in diabetics with renal impairment) Less << - -
NCT02817360 Heart Diseases ... More >> Diabetes Mellitus, Type 2 Less << Phase 4 Recruiting February 2021 Austria ... More >> Internistische Ordination Recruiting Mödling, Niederösterreich, Austria, 2340 Contact: Christian Feinböck, MD    +43 2236 869 142    office@dr-feinboeck.at    Contact: Christiane Feinböck    +43 2236 869 142    office@dr-feinboeck.at    Sub-Investigator: Egbert Seyfried, MD          Principal Investigator: Christian Feinböck, MD          Klinischen Abteilung für Endokrinologie und Diabetologie MU Graz Recruiting Graz, Steiermark, Austria, 8036 Contact: Harald Sourij    +43-316-385-80363    ha.sourij@medunigraz.at    Contact: Michael Zink    +43-680-128-5120    m.zink@medunigraz.at    Sub-Investigator: Julia Mader, MD Prof          Sub-Investigator: Eva Novak, MD          Sub-Investigator: Caren Sourij, MD          Konventhospital der Barmherzigen Brüder Abteilung für Innere Medizin Recruiting Linz, Upper Austria, Austria, 4021 Contact: Martin Clodi, Prof.Dr.       martin.clodi@bblinz.at    Principal Investigator: Martin Clodi, Prof.Dr.          Sub-Investigator: Michael Resl, Dr.          Krankenanstalt Rudolfstiftung, 1. Medizinische Abteilung Recruiting Vienna, Austria, 1030 Contact: Bernhard Ludvik, Prof.Dr.    +43 1 711 65 ext 2107    bernhard.ludvik@wienkav.at    Principal Investigator: Bernhard Ludvik, Prof.Dr.          Sub-Investigator: Eva-Christina Krzizek, Dr.          Sub-Investigator: Johanna Brix, Dr.          Sub-Investigator: Astrid Feder, Dr.          Sub-Investigator: Florian Hoellerl, Dr.          Medical University of Vienna Univ.Clinic for Internal Medicine II Department of Cardiology Recruiting Vienna, Austria, 1090 Contact: Martin Huelsmann, Doz.Dr.    +43 1 40400 ext 46140    martin.huelsmann@meduniwien.ac.at    Principal Investigator: Martin Huelsmann, Doz.Dr.          Sub-Investigator: Raphael Wurm, Dr.          Univ. Klinik für Innere Medizin III Med. Uni Wien Recruiting Vienna, Austria, 1090 Contact: Anton Luger, Prof.Dr.    00 43 1 40400 ext 43100    anton.luger@meduniwien.ac.at    Principal Investigator: Anton Luger, Prof.Dr.          Sub-Investigator: Michael Krebs, Prof.Dr.          Universitätsklinik für Augenheilkunde und Optometrie Medizinische Universität Wien Recruiting Vienna, Austria, 1090 Contact: Sonja Prager, Dr.    +43 1 40400 ext 79470    sonja.prager@meduniwien.ac.at    Principal Investigator: Sonja Prager, Dr.          Sub-Investigator: Julia Hafner, Dr.          Diabetes & Stoffwechselambulanz Gesundheitszentrum Wien Süd Recruiting Vienna, Austria, 1100 Contact: Helmut Brath, OA Dr.    +43 1 60122 ext 4264    helmut.brath@wgkk.at    Principal Investigator: Helmut Brath, OA Dr.          3. Med. Abtlg., KH Hietzing mit Neurologischem Zentrum Rosenhügel Recruiting Vienna, Austria, 1130 Contact: Rudolf Prager, Prof.Dr.    +43 1 80110 ext 2351    rudolf.prager@wienkav.at    Principal Investigator: Rudolf Prager, Prof.Dr.          Sub-Investigator: Slobodan Peric, Dr.          Zentrum für Klinische Studien Recruiting Wien, Austria, 1060 Contact: Ursula Hanusch, MD    +43 1 266 21 91    dr.hanusch@dieinternistin.com    Contact: Michaela Mauritz    +43 1 266 21 91    office@dieinternistin.com    Sub-Investigator: Marita Spak, MD          Netherlands Maastricht University Medical Center; Dep. Cardiology Recruiting Maastricht, Netherlands, 6202 Contact: Hans-Peter Brunner-La Rocca, MD Prof    +31 43-3877097    hp.brunnerlarocca@mumc.nl    Contact: Mireille Spanjers    +31 43-3877099    m.spanjers@mumc.nl    Sub-Investigator: Nick Marks, MD          Sub-Investigator: Wouter Robaeys, MD          New Zealand Christchurch Heart Institute Recruiting Christchurch, New Zealand, 8140 Contact: Richard Troughton, MD Prof    +64 3 364 1063    Richard.Troughton@cdhb.health.nz    Contact: Lorraine Skelton    +64 3 364 1063    lorraine.skelton@cdhb@health.nz    Principal Investigator: Richard Troughton, MD Prof Less <<
NCT01569815 - Completed - -
NCT01569815 Mild and Moderate Renal Impair... More >>ment Less << Phase 1 Completed - Germany ... More >> Novartis Investigative Site Neuss, Germany, 41460 Russian Federation Novartis Investigative Site Moscow, Russian Federation, 117292 Serbia Novartis Investigative Site Belgrade, Serbia Less <<
NCT00741585 Essential Hypertension ... More >> Cardiovascular Disease Stroke Chronic Kidney Disease Less << Phase 4 Completed - Spain ... More >> CS Friol Friol, Lugo, Spain, 27220 CS Baiona Baiona, Pontevedra, Spain, 36300 CS Bueu Bueu, Pontevedra, Spain, 36930 CS A Estrada La Estrada, Pontevedra, Spain, 26680 CS A Guarda La Guardia, Pontevedra, Spain, 36780 CS Valmiñor Nigran, Pontevedra, Spain, 36250 CS Panxón Nigrán, Pontevedra, Spain, 36340 CS Tomiño Tomiño, Pontevedra, Spain, 36200 Bioengineering & Chronobilogy Labs., University of Vigo Vigo, Pontevedra, Spain, 36200 Hospital do Meixoeiro Vigo, Pontevedra, Spain, 36200 CS Calle Cuba Vigo, Pontevedra, Spain, 36202 CS A Doblada Vigo, Pontevedra, Spain, 36205 CS Coia Vigo, Pontevedra, Spain, 36209 CS Sardoma Vigo, Pontevedra, Spain, 36214 CS Teis Vigo, Pontevedra, Spain, 36216 CS Vilaboa Vilaboa, Pontevedra, Spain, 36141 CS San Roque Vilagarcía De Arousa, Pontevedra, Spain, 36600 CS Fingoi Lugo, Spain, 27002 Complexo Hospitalario Universitario de Ourense Orense, Spain, 32005 CS Lerez Pontevedra, Spain, 36156 Less <<
NCT00295542 Hypertension Phase 4 Completed - Spain ... More >> Hospital Clinico Universitario Santiago de Compostela, Spain, 15706 Less <<
NCT00000620 - Completed - -
NCT00000620 Atherosclerosis ... More >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Less << Phase 3 Completed - United States, Minnesota ... More >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Less <<
NCT01715584 Hypertension Phase 4 Recruiting December 31, 2019 Canada, Ontario ... More >> London Health Sciences Centre - Victoria Campus Recruiting London, Ontario, Canada, N6A 5W9 Contact: Craig J Railton, MD, PhD    519 685 8500 ext 58525    Craig.Railton@lhsc.on.ca    Principal Investigator: Craig J Railton, MD, PhD          Sub-Investigator: Jonathan Fairbairn, BSc          Sub-Investigator: George Nicoloau, MD          Sub-Investigator: Robert Gros, PhD          Sub-Investigator: Jason Franklin, MD          Sub-Investigator: John Yoo, MD          Sub-Investigator: Kevin Fung, MD          Sub-Investigator: Anthony Nichols, MD          Sub-Investigator: Danielle McNeil, MD Less <<
NCT00391846 Heart Failure ... More >> Ventricular Dysfunction, Left Less << Phase 4 Completed - Sweden ... More >> Research Site Alvesta, Sweden Research Site Arvika, Sweden Research Site Bjuv, Sweden Research Site Borensberg, Sweden Research Site Bromma, Sweden Research Site Dalby, Sweden Research Site Eskilstuna, Sweden Research Site Gagnef, Sweden Research Site Goeteborg, Sweden Research Site Hisings Karra, Sweden Research Site Huddinge, Sweden Research Site Huskvarna, Sweden Research Site Joenkoeping, Sweden Research Site Kalmar, Sweden Research Site Kungalv, Sweden Research Site Lerum, Sweden Research Site Lessebo, Sweden Research Site Lidkoping, Sweden Research Site Lilla Edet, Sweden Research Site Linkoeping, Sweden Research Site Ludvika, Sweden Research Site Lyckeby, Sweden Research Site Malmo, Sweden Research Site Moheda, Sweden Research Site Motala, Sweden Research Site Orebro, Sweden Research Site Ostersund, Sweden Research Site Skanor, Sweden Research Site Soderakra, Sweden Research Site Stenungsund, Sweden Research Site Stocksund, Sweden Research Site Timra, Sweden Research Site Uddevalla, Sweden Research Site Ulricehamn, Sweden Research Site Umea, Sweden Research Site Uppsala, Sweden Research Site Vasteras, Sweden Research Site Vastervik, Sweden Research Site Vaxjo, Sweden Less <<
NCT00391846 - Completed - -
NCT00661895 Hypertension Phase 4 Completed - United States, Nebraska ... More >> Creighton Community Health Center Omaha, Nebraska, United States, 68104 Less <<
NCT00661895 - Completed - -
NCT01536353 Hypertension Phase 1 Completed - Korea, Republic of ... More >> Asan Medical Center Seoul, Korea, Republic of Less <<
NCT03506412 Heart Failure With Preserved E... More >>jection Fraction Less << Phase 4 Recruiting April 30, 2019 United States, Minnesota ... More >> Mayo Clinic in Rochester Recruiting Rochester, Minnesota, United States, 55905 Less <<
NCT03436147 - Recruiting February 1, 2020 Turkey ... More >> Bakirkoy Dr. Sadi Konuk Training and Research Hospital Recruiting Istanbul, Turkey, 34147 Contact: ismail alay    0905462375638    dr_ismailalay@hotmail.com Less <<
NCT00670787 Hypertension Phase 3 Completed - Japan ... More >> Department of Medicine and Clinical Science, Kyushu University Fukuoka City, Fukuoka, Japan, 812-8582 Less <<
NCT01601470 Mild to Moderate Hypertension Phase 2 Completed - Germany ... More >> Novartis Investigative Site Berlin, Germany, 14050 Less <<
NCT01601470 - Completed - -
NCT01271985 Cardiovascular Diseases Phase 3 Unknown April 2018 Iran, Islamic Republic of ... More >> Golestan Cohort Study Center Gonbad, Golestan, Iran, Islamic Republic of Less <<
NCT00684489 Hypertension Not Applicable Completed - -
NCT03502031 Renal Insufficiency, Chronic ... More >> Diabetic Nephropathy Type 2 Less << Phase 4 Recruiting December 2020 United States, Georgia ... More >> NephroNet Recruiting Buford, Georgia, United States, 30518 Contact: James A Tumlin, MD    770-490-9203    jamestumlinmdnephronet@gmail.com    Contact: Julie Moss    404-790-0267    jmoss@nephronet.com Less <<
NCT00691314 Stroke Transi... More >>ent Ischemic Attack Atherosclerosis Stenosis Stents Less << Not Applicable Completed - China, Beijing ... More >> Beijing Tiantan Hospital Beijing, Beijing, China, 100050 Xuanwu Hospital Capital Medical University Beijing, Beijing, China, 100053 Peking Union Medical College Hospital Beijing, Beijing, China, 100730 China, Chongqing Southwest Hospital Chongqing, Chongqing, China, 400038 Daping Hospital Chongqing, Chongqing, China, 400042 China, Jiangsu Nanjing General Hospital of Nanjing Military Command Nanjing, Jiangsu, China, 210002 China, Jilin Jilin University Changchun, Jilin, China, 130021 China, Shanghai Huashan Hospital Fudan University Shanghai, Shanghai, China, 200040 China, Sichuan West China Center of Medical Sciences Chengdu, Sichuan, China, 610041 China, Tianjin The General Hospital Under Tianjin Medical Sciences University Tianjin, Tianjin, China, 300052 Less <<
NCT00310778 Healthy Phase 1 Completed - France ... More >> Centre d'Investigation Clinique 9201 Hôpital Européen Georges Pompidou Paris, France, 75908 Cedex 15 Less <<
NCT01198496 Hypertension ... More >>Stroke Blood Pressure Less << Phase 4 Recruiting December 2019 Japan ... More >> Jichi Medical Univercity Recruiting Shimotsuke, Tochigi, Japan, 329-0498 Contact: Kazuyuki Shimada, MD       kazuyuki@jichi.ac.jp    Principal Investigator: Kazuomi Kario, MD Less <<
NCT00664846 Stroke Not Applicable Completed - -
NCT02678312 Pediatric Heart Failure Phase 2 Phase 3 Recruiting April 21, 2021 -
NCT02147704 Hypertension Phase 4 Completed - Korea, Republic of ... More >> Clinical Trial Center, Dongguk University Ilsan Hospital Goyang, Gyeonggi-do, Korea, Republic of, 440-710 Less <<
NCT00424801 Microvascular Angina ... More >> Hypertension Less << Not Applicable Terminated(Due to recent findi... More >>ngs relating MRI contrast to nephrogenic systemic fibrosis) Less << December 2008 Denmark ... More >> Aarhus Hospital Aarhus, Denmark, 8000 Less <<
NCT00961207 Microalbuminuria ... More >> Macroalbuminuric Diabetic Nephropathy Diabetes Proteinuria Albuminuria Less << Phase 4 Terminated(Altitude trial whic... More >>h used similar drugs was terminated due to increased ADR.) Less << - United States, Illinois ... More >> John H Stroger Hospital of Cook County Chicago, Illinois, United States, 60612 Less <<
NCT03190304 Heart Failure ... More >> Exercise Tolerance Vasodilation Body Composition Muscle Strength Less << Phase 4 Recruiting December 14, 2018 Brazil ... More >> Marcelo Rodrigues dos Santos Recruiting São Paulo, SP, Brazil, 05403-900 Contact: Antonio P Barreto, PhD    +55 11 2661-5043    pereira.barreto@incor.usp.br Less <<
NCT02966717 Renal Insufficiency, Chronic ... More >> Nephrotic Syndrome Less << Phase 2 Active, not recruiting October 2021 China, Guangdong ... More >> Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China, 510282 Less <<
NCT01621633 Hepatic Impairment Phase 2 Completed - Germany ... More >> Novartis Investigative Site Grunstadt, Germany, D-67269 Less <<
NCT01621633 - Completed - -
NCT01776047 Healthy Male Volunteer Phase 1 Completed - -
NCT01805362 Chronic Kidney Disease Not Applicable Unknown February 2017 France ... More >> Department of Nephrology, Nice University Hospital Recruiting Nice, France, 06000 Contact: vincent Esnault, MD       esnault.v@chu-nice.fr    Principal Investigator: Vincent Esnault, MD Less <<
NCT03035474 Heart Failure Not Applicable Recruiting July 2020 -
NCT03005184 Heart Failure NYHA Class I ... More >> Heart Failure NYHA Class II Heart Failure NYHA Class III Less << Phase 2 Withdrawn(Study is being redes... More >>igned and submitted as a new study.) Less << January 2020 United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less <<
NCT01922089 Heart Failure With Reduced Eje... More >>ction Fraction Less << Phase 2 Completed - -
NCT01922089 - Completed - -
NCT02966665 Chronic Obstructive Pulmonary ... More >>Disease Pulmonary Artery Hypertension Heart Failure Hypertension Less << Phase 1 Recruiting August 2020 United States, Utah ... More >> George E Wahlen VA Medical Center Recruiting Salt Lake City, Utah, United States, 84132 Contact: Russell Richardson, Ph.D.    801-582-1565    r.richardson@hsc.utah.edu    Contact: Ashley Nelson, MD    801-582-1565 ext 4127    ash.nelson@hsc.utah.edu Less <<
NCT01377285 Chronic Renal Failure Phase 4 Unknown December 2018 Taiwan ... More >> National Taiwan University Hospital Recruiting Taipei, Taiwan, 100 Contact: Tun-Jun Tsai, M.D.; PhD    00886-2-23123456 ext 63953    tjtsai@ntuh.gov.tw    Contact: Yung-Ming Chen, M.D.    00886-2-23123456 ext 65993    chenym@ntuh.gov.tw    Principal Investigator: Tun-Jun Tsai, M.D.; PhD Less <<
NCT00200694 Heavy Proteinuria Phase 4 Terminated(difficulty in patie... More >>nts's inclusion) Less << - France ... More >> CHU de Nantes Nantes, France Less <<
NCT01870739 Hypertension Phase 2 Completed - Germany ... More >> Novartis Investigative Site Berlin, Germany, 10117 Novartis Investigative Site Erlangen, Germany, 91054 Switzerland Novartis Investigative Site Basel, Switzerland, 4031 United Kingdom Novartis Investigative Site Glasgow, Scotland, United Kingdom, G12 8TA Less <<
NCT00949351 Type 2 Diabetes With Nephropat... More >>hy Less << Phase 4 Unknown September 2010 Thailand ... More >> Lerdsin General Hospital Not yet recruiting Bangkok, Thailand, 10500 Contact: Krissanapong Manotham, Dr    662 3539799 ext 2501    kmanotham@hotmail.com    Contact: Tanaporn Ratanasuwan, Dr       tratanas@hotmail.com    Principal Investigator: Krissanapong Manotham, Dr Less <<
NCT00518479 Hypertension ... More >>Left Ventricular Hypertrophy Less << Not Applicable Completed - United Kingdom ... More >> Leeds Teaching Hospital NHS Trust Leeds, Wesst Yorkshire, United Kingdom, LS1 3EX Less <<
NCT01870739 - Completed - -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.30mL

0.46mL

0.23mL

11.48mL

2.30mL

1.15mL

22.96mL

4.59mL

2.30mL

References

 

Historical Records

Categories