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Chemical Structure| 138-60-3 Chemical Structure| 138-60-3

Structure of Chelidamic acid
CAS No.: 138-60-3

Chemical Structure| 138-60-3

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Chelidamic acid is a pharmaceutical intermediate as well as a cosmetic material due to its anti-inflammatory and whitening effect.

Synonyms: Chelidamic acid hydrate

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Product Citations

Product Citations

Lew, Maria JH ; Kelber, Jacob A ; Van Vleet, Mary J ; Johnson, Adam R ; Jarvo, Elizabeth R ; Williams, Nancy SB

Abstract: A strong π-donor, weak σ-donor pyridonate pincer complex of is reported, a rare but important electronic ligand structure for promoting in late transition metals. Protonation of the complex 2,6-bis(diethylaminomethyl)-4- pyridonate platinum(II) methyl occurs initially at oxygen, with a second proton equivalent affording methane. Methyl triflate similarly methylates initially with oxygen and then . A computational study indicates that this terdentate pyridonate pincer greatly enhances the ability of late transition metals to cleave the C-H bond of methane compared to a classic NCN pincer. With bound to this π-donor pincer, the oxidative addition of methane is computationally predicted to be thermodynamically favorable.

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Product Details of Chelidamic acid

CAS No. :138-60-3
Formula : C7H5NO5
M.W : 183.12
SMILES Code : O=C(C1=CC(C=C(C(O)=O)N1)=O)O
Synonyms :
Chelidamic acid hydrate
MDL No. :MFCD00066478
InChI Key :XTLJJHGQACAZMS-UHFFFAOYSA-N
Pubchem ID :8743

Safety of Chelidamic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.46mL

1.09mL

0.55mL

27.30mL

5.46mL

2.73mL

54.61mL

10.92mL

5.46mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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