Home Cart Sign in  
Chemical Structure| 1384427-80-8 Chemical Structure| 1384427-80-8

Structure of 1384427-80-8

Chemical Structure| 1384427-80-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1384427-80-8 ]

CAS No. :1384427-80-8
Formula : C13H15NO2
M.W : 217.26
SMILES Code : O=C1C2CN(CC3=CC=CC=C3)CC1OC2
MDL No. :MFCD22196365

Safety of [ 1384427-80-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1384427-80-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1384427-80-8 ]

[ 1384427-80-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 22929-52-8 ]
  • [ 50-00-0 ]
  • [ 100-46-9 ]
  • [ 1384427-80-8 ]
YieldReaction ConditionsOperation in experiment
20% With acetic acid; In methanol; at 23℃; for 20h;Reflux; Inert atmosphere; a)(rac)-3-Benzyl-6-oxa-3-aza-bicyclo[3.2.1]octan-8-oneA solution of benzylamine (1.26 mL, 11.6 mmol) in methanol (2 mL) was added drop wise to a refluxing solution of dihydro-furan-3-one (1 g, 11.6 mmol), paraformaldehyde (1.04 g, 34.84 mmol), and glacial acetic acid (0.67 mL, 11.61 mmol) in methanol (8 mL) over a period of 3 hours under nitrogen.Reflux was continued for 1 hour after which, the brown reaction mixture was stirred at 23° C. for 16 hours.The reaction mixture was concentrated in vacuo.The resulting oil was diluted with water and basified with 6 N aqueous NaOH solution.The aqueous solution was extracted with ethyl acetate, washed with water, brine, dried over sodium sulfate, filtered and concentrated under reduced pressure.The crude product was purified by flash column chromatography on silica gel with 25-30percent ethyl acetate in hexane as eluent.The title compound was obtained as a colorless sticky liquid (500 mg, 20percent).
 

Historical Records