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Chemical Structure| 13862-13-0 Chemical Structure| 13862-13-0

Structure of 13862-13-0

Chemical Structure| 13862-13-0

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Product Details of [ 13862-13-0 ]

CAS No. :13862-13-0
Formula : C7H6I2O2
M.W : 375.93
SMILES Code : OC1=C(I)C=C(I)C=C1CO

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Application In Synthesis of [ 13862-13-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13862-13-0 ]

[ 13862-13-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2631-77-8 ]
  • [ 13862-13-0 ]
YieldReaction ConditionsOperation in experiment
91% With methanol; sodium tetrahydroborate; at 25℃; for 19h;Cooling with ice; 90 g (0.24 mol) of <strong>[2631-77-8]3,5-diiodosalicylaldehyde</strong> was dissolved in 900 ml of methanol, and 22.8 g (0.60 mol) of NaBH4 was added at 10C or lower. Then, after stirring for 3 hours under ice cooling, it was stirred at 25C for 16 hours for reaction, and methanol was distilled off under reduced pressure and concentrated. Water and ethyl acetate are added to the concentrate, and the organic phase is extracted.Magnesium sulfate was added to this organic phase and dried, and the solvent was distilled off under reduced pressure to obtain a crude product of 2-hydroxy-3,5-diiodobenzyl alcohol. The resulting crude product of 2-hydroxy-3,5-diiodobenzyl alcohol was purified by column chromatography,82.5 g of 2-hydroxy-3,5-diiodobenzyl alcohol shown below was obtained (yield 91%).
 

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