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Chemical Structure| 1401462-04-1 Chemical Structure| 1401462-04-1

Structure of 1401462-04-1

Chemical Structure| 1401462-04-1

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Product Details of [ 1401462-04-1 ]

CAS No. :1401462-04-1
Formula : C7H11BrN2O
M.W : 219.08
SMILES Code : O=C1NC=CC(CCN)=C1.[H]Br
MDL No. :MFCD31561507

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Application In Synthesis of [ 1401462-04-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1401462-04-1 ]

[ 1401462-04-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1401462-03-0 ]
  • [ 1401462-04-1 ]
YieldReaction ConditionsOperation in experiment
86% With hydrogen bromide; In acetic acid; for 4.0h;Reflux; Step 4 4-(2-Aminoethyl)pyridin-2(1H)-one hydrobromide Procedure: A solution of <strong>[1401462-03-0]2-(2-methoxypyridin-4-yl)ethanamine hydrochloride</strong> (0.8 g, 4.23 mmol) was dissolved in 45% HBr (7 mL) and HOAc (7 mL). The mixture was heated to reflux for 4 hours and then the solvent was removed under reduce pressure. The residue was washed with THF (20 mL) and dried to give 4-(2-aminoethyl)pyridin-2(1H)-one hydrobromide (0.8 g 86%) as a grey solid. LC-MS: 139 [M+H]+, tR=0.28 min.
 

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