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Chemical Structure| 14034-90-3 Chemical Structure| 14034-90-3

Structure of 14034-90-3

Chemical Structure| 14034-90-3

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Product Details of [ 14034-90-3 ]

CAS No. :14034-90-3
Formula : C11H13NO4
M.W : 223.23
SMILES Code : O=C(O)C1=CC([N+]([O-])=O)=CC=C1C(C)(C)C
MDL No. :MFCD09965934

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Application In Synthesis of [ 14034-90-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14034-90-3 ]

[ 14034-90-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1077-58-3 ]
  • [ 14034-90-3 ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid; potassium nitrate; at 0℃; Compound 44b was dissolved in concentrated H2SO4 (25 mL) and cooled to 0 C. Then a solutionof KNO3 (20 mmol) in concentrated H2SO4 (25 mL) was dropwise added to the mixture. The mixturewas reacted at 0 C until the reaction was completed, and dropwise added to ice water. The resultedmixture was filtered and washed with water. The filter cake was dried and crystallized from EtOHto give intermediate 44b in yield of 40% over two steps. 1H-NMR (DMSO-d6): 13.75 (s, 1H), 8.21(dd, J = 8.8, 2.8 Hz, 1H), 8.10 (d, J = 2.8 Hz, 1H), 7.80 (d, J = 8.8 Hz, 1H), 1.43 (s, 9H) ppm; 13C-NMR(DMSO-d6): 170.88, 153.99, 144.99, 135.54, 128.88, 123.82, 122.76, 36.35, 30.62 ppm.
 

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