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Chemical Structure| 1427391-09-0 Chemical Structure| 1427391-09-0

Structure of 1427391-09-0

Chemical Structure| 1427391-09-0

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Product Details of [ 1427391-09-0 ]

CAS No. :1427391-09-0
Formula : C9H11BrN2
M.W : 227.10
SMILES Code : CN1CCNC2=C1C=C(Br)C=C2
MDL No. :MFCD23708979

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Application In Synthesis of [ 1427391-09-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1427391-09-0 ]

[ 1427391-09-0 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 106-93-4 ]
  • [ 337915-79-4 ]
  • [ 1427391-09-0 ]
YieldReaction ConditionsOperation in experiment
233.0 mg With tetrabutylammomium bromide; at 60℃; for 12h; A mixture of 5-bromo-M-m ethylbenzene- 1, 2-diamine (1.0 g, 4.97 mmol), 1,2- dibromoethane (2.13 mL, 24.8 mmol) and TBAB (4.80 g, 14.9 mmol) was stirred at 60 C for 12 hours. The mixture was concentrated in vacuo and purified by flash silica gel chromatography (petroleum ether/EtOAc = 1/0 to 2/1) to give 7-bromo- 1 -methyl- 1,2, 3,4- tetrahydroquinoxaline (233.0 mg, 21% yield) as a brown solid. LCMS m/z [M+H]+ = 226.9/228.9.
 

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