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Chemical Structure| 1431869-34-9 Chemical Structure| 1431869-34-9

Structure of 1431869-34-9

Chemical Structure| 1431869-34-9

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Product Details of [ 1431869-34-9 ]

CAS No. :1431869-34-9
Formula : C7H3ClINS
M.W : 295.53
SMILES Code : IC1=CC2=CC=C(Cl)N=C2S1
MDL No. :MFCD28658281

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Application In Synthesis of [ 1431869-34-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1431869-34-9 ]

[ 1431869-34-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 62226-18-0 ]
  • [ 1431869-34-9 ]
YieldReaction ConditionsOperation in experiment
With N-iodo-succinimide; In trifluorormethanesulfonic acid; at 20℃; for 4.0h; Step A: 6-Chloro-2-iodothieno[Z3-b1pyridine: To a flask charged with 6-Chlorothieno[2,3- b]pyridine (500 mg, 3.0 mmol) and a stir bar was added NIS (800 mg, 3.5 mmol) and Triflic acid (5 mL). The mixture was monitored by TLC and allowed to stir at RT for 4 hours. The reaction was poured into ice, neutralized with aqueous sodium carbonate, extracted with DCM, dried over sodium sulfate, concentrated and purified by flash chromatography (Hex: EtOAc gradient) to obtain the title product. LC-MS (IE, tn/z): 296 [M + 1]+.
 

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