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Chemical Structure| 14377-33-4 Chemical Structure| 14377-33-4

Structure of 14377-33-4

Chemical Structure| 14377-33-4

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Product Details of [ 14377-33-4 ]

CAS No. :14377-33-4
Formula : C15H21ClO
M.W : 252.78
SMILES Code : O=C(Cl)C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1

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Application In Synthesis of [ 14377-33-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14377-33-4 ]

[ 14377-33-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 14377-33-4 ]
  • [ 30757-50-7 ]
  • 3,4-dicyanophenyl 3,5-di-tert-butylbenzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% With sodium hydroxide; In water; at 25 - 50℃; for 2h; 4-Hydroxyphthalodinitrile (1) (1.73 g, 0.01 mol) was dissolved in 50 mL of 10% NaOH solution. Then, 3,5-di-tert-butylbenzoyl chloride (2) (3.8 g, 0.015 mol) was added under stirring. The resulting suspension was stirred at 25 C for 1 h, and then at 40-50 C for another hour. The reaction mixture was cooled, poured into 200 mL of water. The resulting precipitate was filtered off, washed with 50 mL of water, and recrystallized from 95% ethanol. The yield of the target product was 2.5 g (70%). M.p. 149-151 C. IR (KBr), ν/cm-1: 2960, 2870 m (CH3), 2235 m (C≡N), 1737 s (C=O), 1599, 1482 m (C=CAr), 1225 s (C-O), 1108. 1H NMR (CDCl3), δ: 8.03 (d, 2 H, H(15,16), 4J = 1.8 Hz); 7.91 (d, 1 H, H(4), 3J =8.6 Hz); 7.79 (t, 1 H, H(19), 4J = 1.8 Hz); 7.77 (d, 1 H, H(3), 4J = 2.2 Hz); 7.68 (dd, 1 H, H(2), 3J = 8.7 Hz, 4J = 2.3Hz); 1.41 (s, 18 H, But). 13C NMR (CDCl3) δ: 31.33, 35.07, 112.93, 114.62, 114.98, 117.40, 124.64, 127.15, 127.30, 127.45, 129.08, 134.97, 151.89, 154.41, 164.46.
 

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