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Chemical Structure| 148473-84-1 Chemical Structure| 148473-84-1

Structure of 148473-84-1

Chemical Structure| 148473-84-1

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Product Details of [ 148473-84-1 ]

CAS No. :148473-84-1
Formula : C13H19NO
M.W : 205.30
SMILES Code : OC1CN(CC2=CC=CC=C2)CCCC1
MDL No. :MFCD27998080

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Application In Synthesis of [ 148473-84-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 148473-84-1 ]

[ 148473-84-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 146407-32-1 ]
  • [ 148473-84-1 ]
YieldReaction ConditionsOperation in experiment
100% With lithium aluminium tetrahydride; In diethyl ether; at 20℃; for 0.5h; Under a nitrogen atmosphere, lithium aluminum hydride (1.4 mg, 0.0369 mmol) was added to a solution of <strong>[146407-32-1]1-benzylazepan-3-one</strong> (15 mg, 0.0738 mmol) in diethyl ether (1 ml) at 0C, and the resulting mixture was heated to room temperature. After 30 minutes, water, a 2M-aqueous sodium hydroxide solution and water were added in that order to the reaction solution. The resulting mixture was filtered by the use of Celite, and the filtrate was concentrated under reduced pressure and the resulting residue was purified by a silica gel column chromatography (eluent: chloroform/methanol) to obtain 1-benzylazepan-3-ol (16.2 mg, 100%).
 

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