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Chemical Structure| 148560-00-3 Chemical Structure| 148560-00-3

Structure of 148560-00-3

Chemical Structure| 148560-00-3

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Product Details of [ 148560-00-3 ]

CAS No. :148560-00-3
Formula : C11H22ClNO
M.W : 219.75
SMILES Code : O=C(N(C)CCCCCCCC)CCl
MDL No. :MFCD24465133

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Application In Synthesis of [ 148560-00-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 148560-00-3 ]

[ 148560-00-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2439-54-5 ]
  • [ 79-04-9 ]
  • [ 148560-00-3 ]
YieldReaction ConditionsOperation in experiment
66.4% In diethyl ether; at -2℃; for 3h; Chloroacetyl chloride in diethylether was added dropwise to N-methyloctylamine in diethylether at ?2° C. The organic solution was returned to room temperature, followed by stirring for 3 hours. The resulting solution was successively washed with an aqueous 1 mol/L hydrochloric acid solution and water, and then dried over anhydrous sodium sulfate. After removal the solvent under vacuum, the residue was purified by silica gel column chromatography (hexane:ethyl acetate=23:2) to give N-methyl-N-octyl-chloroacetamide (yield: 66.4percent). (0087) The analytical results of the resultant product are shown blow. (0088) IR (neat, vcm?1): 1658 (C?O). (0089) Elementary analysis: Found: C=59.51percent; H=10.00percent; N=6.25percent. (0090) Calculated for C11H22NOCl: C=60.12percent; H=10.10percent; N=6.37percent. (0091) 1H-NMR (400 MHz, CDCl3, tauppm): (0092) 0.88(3H, CH2CH3); 1.2 to 1.4(10H, CH3(CH2)5; 1.5 to 1.7(2H, NCH2CH2), 2.96 and 3.07(3H, NCH3); 3.25 to 3.40(2H, NCH2); 4.09 (2H, ClCH2CO)
 

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