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Chemical Structure| 151225-38-6 Chemical Structure| 151225-38-6

Structure of 151225-38-6

Chemical Structure| 151225-38-6

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Product Details of [ 151225-38-6 ]

CAS No. :151225-38-6
Formula : C8H8N2O3
M.W : 180.16
SMILES Code : O=[N+](C1=CN=C2C(COCC2)=C1)[O-]

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Application In Synthesis of [ 151225-38-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 151225-38-6 ]

[ 151225-38-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 29943-42-8 ]
  • [ 14150-94-8 ]
  • [ 151225-38-6 ]
YieldReaction ConditionsOperation in experiment
47% With ammonia; In methanol; at 50℃; for 18h;Sealed tube; In a sealed tube, a solution of tetrahydro-4H-pyran-4-one (2.00 g, 19.98 mmol) and <strong>[14150-94-8]1-methyl-3,5-dinitro-1H-pyridin-2-one</strong> (3.98 g, 19.98 mmol) in ammonia (7N in MeOH) (34mL) was stirred at 50 C for 18 h. After cooling down to rt, the mixture was diluted withDCM and a saturated aqueous solution of NaHCO3 was added. The aqueous layer was separated and extracted with DCM (three times). The combined organic layers were dried over MgSO4, filtered off and evaporated in vacuo to give 1.70 g of intermediate 100 (47% yield, red solid).
 

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