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Chemical Structure| 15263-75-9 Chemical Structure| 15263-75-9

Structure of 15263-75-9

Chemical Structure| 15263-75-9

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Product Details of [ 15263-75-9 ]

CAS No. :15263-75-9
Formula : C7H10ClN3O2
M.W : 203.63
SMILES Code : C[N+](C)=CC1=C(O)N=CNC1=O.[Cl-]

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Application In Synthesis of [ 15263-75-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 15263-75-9 ]

[ 15263-75-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 68-12-2 ]
  • [ 1193-24-4 ]
  • [ 15263-75-9 ]
YieldReaction ConditionsOperation in experiment
139.4 g Add DCM (600ml) and POCl3 (80ml, 862mmol) to the reaction flask, stir evenly, and pass through nitrogenThe mixture was cooled to 5-10 C, and a solution of DMF (66.04 ml, 856 mmol) dissolved in DCM (200 ml) was added dropwise, and the mixture was stirred for 15-20 min, heated to 25-30 C, and stirred for 1-2 hours. 4,6-Dihydroxypyrimidine (80 g, 714 mmol) was added to the reaction mixture, and the reaction was carried out at 25-30 C for 22 hours, filtered, and the filter cake was washed twice with DCM (150 ml), dried, and vacuum at 40-45 C Drying gave 139.4 g of a yellow solid as the desired compound.
 

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