Structure of Hemin
CAS No.: 16009-13-5
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Hemin, an iron-containing porphyrin, acts as an inducer of Heme oxygenase (HO)-1.
Synonyms: Hemin chloride; protohemin; Chloro(protoporphyrinato)iron(III), Chlorohemin, Chloroprotoporphyrin IX iron(III), Ferriprotoporphyrin IX chloride, Hemin(chloride)
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CAS No. : | 16009-13-5 |
Formula : | C34H32ClFeN4O4 |
M.W : | 651.94 |
SMILES Code : | [Cl-][Fe+3]123[N-]4C5=C(CCC([O-])=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC([O-])=O)=[N]3C8=C5.[H+].[H+] |
Synonyms : |
Hemin chloride; protohemin; Chloro(protoporphyrinato)iron(III), Chlorohemin, Chloroprotoporphyrin IX iron(III), Ferriprotoporphyrin IX chloride, Hemin(chloride)
|
MDL No. : | MFCD00010726 |
InChI Key : | BTIJJDXEELBZFS-UHFFFAOYSA-K |
Pubchem ID : | 455658 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT01817530 | Heavy Uterine Bleeding ... More >> Uterine Fibroids Less << | Phase 2 | Completed | - | - |
NCT03086681 | Cervical Carcinoma | Phase 3 | Not yet recruiting | February 2020 | China, Guangxi ... More >> First Affiliated Hospital of Guangxi Medical University Not yet recruiting Nanning, Guangxi, China, 530021 Contact: Yong Zhang, M.D. 0086-13607884001 zhangyonggx@163.com Contact: Fang Wu, M.D. Sub-Investigator: Jian Li, M.D. Sub-Investigator: Hemin Lu, M.D. Sub-Investigator: Haixin Huang, Master Sub-Investigator: Zhanxiong Luo, Master Sub-Investigator: Meilian Liu, Master Sub-Investigator: Gaojuan Lin, Master Sub-Investigator: Sihui Liao, bachelor Sub-Investigator: Hongqian Wang, bachelor Less << |
NCT00307801 | Metrorrhagia | Phase 3 | Completed | - | - |
NCT00293059 | Metrorrhagia | Phase 3 | Completed | - | - |
NCT00307801 | - | Completed | - | - | |
NCT03338816 | Acute Hepatic Porphyria ... More >> Acute Intermittent Porphyria Porphyria, Acute Intermittent Acute Porphyria Hereditary Coproporphyria (HCP) Variegate Porphyria (VP) ALA Dehydratase Deficient Porphyria (ADP) Less << | Phase 3 | Active, not recruiting | September 2021 | - |
NCT02949830 | Acute Intermittent Porphyria | Phase 1 Phase 2 | Active, not recruiting | August 2020 | United States, California ... More >> Clinical Trial Site San Francisco, California, United States United States, New York Clinical Trial Site New York, New York, United States United States, Texas Clinical Trial Site Galveston, Texas, United States Sweden Clinical Trial Site Stockholm, Sweden United Kingdom Clinical Trial Site London, United Kingdom Less << |
NCT00293059 | - | Completed | - | - | |
NCT02082860 | Acute Intermittent Porphyria | Phase 1 | Completed | - | Spain ... More >> Clinica Universidad de Navarra Pamplona, Navarra, Spain, 31008 12 Octubre Hospital Madrid, Spain, 28041 Less << |
NCT01504308 | Uterine Fibroids | Phase 2 Phase 3 | Terminated(It was not possible... More >> to enroll patients into the study in a realistic timeframe.) Less << | - | United States, Illinois ... More >> University of Chicago Chicago, Illinois, United States, 60637 United States, Michigan University of Michigan Ann Arbor, Michigan, United States, 48109 United States, New York Montefiore Medical Center Bronx, New York, United States, 10467 United States, Oregon Oregon Science and Health University Portland, Oregon, United States, 97239 United States, Tennessee Vanderbilt Medical Center Nashville, Tennessee, United States, 37232 United States, Texas University of Texas Southwestern Medical Center Dallas, Texas, United States, 75235 St. Luke's Episcopal Hospital Houston, Texas, United States, 77030 Canada, Ontario Sunnybrook Health Sciences Centre Toronto, Ontario, Canada Korea, Republic of Samsung Medical Center Seoul, Korea, Republic of Less << |
NCT01735812 | Symptomatic Uterine Fibroids | Not Applicable | Unknown | - | Israel ... More >> Assaf Harofe Recruiting Zrifin, Israel, 70300 Contact: Moty Pansky, Prof. Principal Investigator: Moty Pansky, Prof Less << |
NCT02985541 | Contraception | Phase 3 | Active, not recruiting | June 4, 2021 | - |
NCT02654054 | Uterine Fibroids ... More >> Heavy Menstrual Bleeding Less << | Phase 3 | Active, not recruiting | December 19, 2018 | - |
NCT02794467 | Adenomyosis | Phase 2 | Withdrawn(Study was prematurel... More >>y discontinued due to GSK's change in prioritization for the portfolio and is not due to any safety concerns or regulatory interaction.) Less << | October 2016 | United States, District of Col... More >>umbia GSK Investigational Site Washington, DC, District of Columbia, United States, 20036 United States, Florida GSK Investigational Site West Palm Beach, Florida, United States, 33409 United States, Illinois GSK Investigational Site Champaign, Illinois, United States, 61820 United States, Louisiana GSK Investigational Site Mandeville, Louisiana, United States, 70471 GSK Investigational Site Metairie, Louisiana, United States, 70006 United States, Nebraska GSK Investigational Site Lincoln, Nebraska, United States, 68510 United States, Nevada GSK Investigational Site Las Vegas, Nevada, United States, 89128 United States, New Jersey GSK Investigational Site Lawrenceville, New Jersey, United States, 08648 United States, North Carolina GSK Investigational Site Durham, North Carolina, United States, 27713 GSK Investigational Site Raleigh, North Carolina, United States, 27612 United States, Ohio GSK Investigational Site Englewood, Ohio, United States, 45322 United States, Pennsylvania GSK Investigational Site Pittsburgh, Pennsylvania, United States, 15206 United States, Texas GSK Investigational Site Houston, Texas, United States, 77030 Less << |
NCT01569763 | Menorrhagia | Not Applicable | Completed | - | United States, Arizona ... More >> New Horizons Women's Care Chandler, Arizona, United States, 85224 Women's Health Research Phoenix, Arizona, United States, 85015 United States, Indiana Basinski, LLC Newburgh, Indiana, United States, 47630 United States, Kansas Cypress Medical Research Center, LLC Wichita, Kansas, United States, 67226 United States, Minnesota Minnesota Gynecology and Surgery Edina, Minnesota, United States, 55435 United States, Missouri Mercy Clinic Minimally Invasive Gynecology Saint Louis, Missouri, United States, 63141 United States, Tennessee Tennessee Women's Care PC Nashville, Tennessee, United States, 37203 United States, Texas Baylor Research Institute Fort Worth, Texas, United States, 76104 Canada, Ontario McMaster University/Hamilton Health Sciences Hamilton, Ontario, Canada, L8N3Z5 Canada, Quebec Hôpital LaSalle Ville Lassalle, Quebec, Canada, H8P 1C1 Canada, Saskatchewan Regina Qu'Appelle Health Region Regina, Saskatchewan, Canada, S4S 6X3 Canada La Cite Medicale Quebec, Canada, G1W 2J5 Mexico Hospital Universitario, UANL Monterrey, Nuevo Leon, Mexico, 64460 Less << |
NCT01199159 | Hysterectomy | Not Applicable | Completed | - | Hong Kong ... More >> University of Hong Kong Hong Kong, Hong Kong Less << |
NCT03271489 | Heavy Menstrual Bleeding ... More >> Uterine Fibroids Less << | Phase 3 | Recruiting | May 16, 2022 | - |
NCT03049735 | Heavy Menstrual Bleeding ... More >> Uterine Fibroid Less << | Phase 3 | Active, not recruiting | December 30, 2019 | - |
NCT03412890 | Heavy Menstrual Bleeding ... More >> Uterine Fibroid Less << | Phase 3 | Enrolling by invitation | July 30, 2020 | United States, Arizona ... More >> Mesa Mesa, Arizona, United States, 85209 United States, Colorado Denver Denver, Colorado, United States, 80209 United States, Florida Margate Margate, Florida, United States, 33063 United States, Louisiana Metairie Metairie, Louisiana, United States, 70001 United States, Nevada Las Vegas Las Vegas, Nevada, United States, 89128 United States, Ohio Englewood Englewood, Ohio, United States, 45322 United States, Texas Houston Houston, Texas, United States, 77054 Less << |
NCT01675011 | - | Terminated(Inadequate enrollme... More >>nt) Less << | - | - | |
NCT01569763 | - | Completed | - | - | |
NCT01276964 | - | Unknown | September 2012 | Italy ... More >> University of L'Aquila Recruiting L'aquila, Italy, 67100 Contact: napolitano marysanta@libero.it Principal Investigator: napolitano mariasanta, md University of Palermo Active, not recruiting Palermo, Italy, 90127 Casa Sollievo Della Sofferenza Irccs Recruiting San Giovanni Rotondo, Italy, 71013 Contact: grandone grandone@katamail.com Principal Investigator: elvira grandone, md Less << | |
NCT02076763 | - | Completed | - | Spain ... More >> Clinica Universidad de Navarra Pamplona, Navarra, Spain, 31008 12 Octubre Hospital Madrid, Spain, 28041 Less << | |
NCT02691494 | Uterine Fibroids ... More >> Heavy Menstrual Bleeding Less << | Phase 3 | Active, not recruiting | January 16, 2019 | - |
NCT01675011 | Uterine Fibroids | Not Applicable | Terminated(Inadequate enrollme... More >>nt) Less << | - | United States, New York ... More >> Albany Medical Center Albany, New York, United States North Shore LIJ Medical Center New Hyde Park, New York, United States Less << |
NCT01715025 | Menorrhagia | Phase 4 | Unknown | August 2015 | Australia, New South Wales ... More >> SCRHR Recruiting Sydney, New South Wales, Australia, 2131 Principal Investigator: Edith Weisberg, MB BS MM Less << |
NCT03103087 | Heavy Menstrual Bleeding ... More >> Uterine Fibroid Less << | Phase 3 | Active, not recruiting | February 28, 2020 | - |
NCT03070951 | Uterine Fibroids ... More >> Heavy Menstrual Bleeding Less << | Phase 3 | Recruiting | November 2019 | - |
NCT02925494 | Uterine Fibroids ... More >> Heavy Menstrual Bleeding Less << | Phase 3 | Active, not recruiting | April 8, 2019 | - |
NCT02131662 | Leiomyoma | Phase 2 | Completed | - | - |
NCT03751124 | Uterine Leiomyoma ... More >> Uterine Fibroids Less << | Phase 3 | Enrolling by invitation | March 31, 2021 | United States, Florida ... More >> United States, Florida West Palm Beach, Florida, United States, 33409 Less << |
NCT02131662 | - | Completed | - | - | |
NCT02935400 | Acute Intermittent Porphyria|H... More >>ereditary Coproporphyria|Variegate Porphyria Less << | ACTIVE_NOT_RECRUITING | 2025-12-31 | University of Texas Medical Br... More >>anch, Galveston, Texas, 77555, United States Less << | |
NCT02180412 | Acute Porphyrias | Phase 2 | Recruiting | August 31, 2020 | United States, Texas ... More >> University of Texas Medical Branch Recruiting Galveston, Texas, United States, 77555 Contact: Karl E Anderson, MD 409-772-4661 kanderso@utmb.edu Contact: Csilla Hallberg, MD 409-772-4661 challberg@utmb.edu Principal Investigator: Karl E Anderson, MD Less << |
NCT00467610 | - | Terminated(lack of efficacy.) | - | - | |
NCT03070899 | Uterine Fibroids ... More >> Heavy Menstrual Bleeding Less << | Phase 3 | Recruiting | February 2020 | - |
NCT01430156 | Graft Failure ... More >> Ischemia-reperfusion Injury Less << | Phase 3 | Completed | - | United Kingdom ... More >> Royal Infirmary of Edinburgh/ University of Edinburgh Edinburgh, Lothian, United Kingdom, EH16 4TJ Less << |
NCT01206582 | Gastroparesis ... More >> Diabetes Mellitus Less << | Phase 2 | Completed | - | United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55901 Less << |
NCT00882804 | Healthy Volunteers | Phase 1 | Completed | - | United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less << |
NCT01206582 | - | Completed | - | - | |
NCT01855841 | Post-ERCP Acute Pancreatitis | Phase 2 | Recruiting | February 2019 | Belgium ... More >> CHU Brugmann Terminated Brussels, Belgium, 1020 Erasme Hospital, Université Libre de Bruxelles (ULB) Recruiting Brussels, Belgium, 1070 Contact: Arnaud Lemmers, MD, PhD +3225556559 arnaud.lemmers@erasme.ulb.ac.be Contact: Mohammed Amrani +3225558382 mohammed.amrani@erasme.ulb.ac.be Principal Investigator: Arnaud Lemmers, MD, PhD Sub-Investigator: Olivier Le Moine, MD, PhD Sub-Investigator: Jacques Devière, MD, PhD Sub-Investigator: Myriam Delhaye, MD, PhD Sub-Investigator: Marianna Arvanitakis, MD, PhD Centre Hospitalier de Jolimont-Lobbes Recruiting Haine-St-Paul, Belgium, 7100 Contact: Didier Verset, MD +32 478 421 493 didier.verset@skynet.be Principal Investigator: Didier Verset, MD CHU Liège Sart Tilman Not yet recruiting Liège, Belgium, 4000 Contact: Jean-Philippe Loly, MD 04/366.74.39 jp.loly@hotmail.com Contact: Wertz Sylvie 04/366.74.39 swertz@chu.ulg.ac.be Hôpital Ambroise Paré Recruiting Mons, Belgium, 7000 Contact: Axel Hittelet, MD 065.39.37.48 axel.hittelet@hap.be Principal Investigator: Axel Hittelet, MD ISPPC CHU Vésale Terminated Montigny Le tilleul, Belgium, 6110 Italy San Raffaele Scientific Institute, Vita Salute San Raffaele University Not yet recruiting Milan, Italy, 20132 Contact: MariaChiara Petrone, MD petrone.mariachiara@hsr.it Principal Investigator: MariaChiara Petrone, MD Policlinico Gemelli Universita Cattolica Not yet recruiting Rome, Italy, 00168 Contact: Guido Costamagna, MD 06.35511515 gcostamagna@rm.unicatt.it Principal Investigator: Guido Costamagna, MD Sub-Investigator: Andrea Tringali, MD Taiwan National Taiwan University Hospital Recruiting Taipei, Taiwan Contact: Wei-Chih Liao, MD,PhD david.ntuh@gmail.com Principal Investigator: Wei-Chih Liao, MD,PhD Less << |
NCT00467610 | Myelodysplastic Syndrome | Phase 2 | Terminated(lack of efficacy.) | - | United States, Illinois ... More >> Rush University Medical Center Chicago, Illinois, United States, 60612 Less << |
NCT02922413 | Acute Intermittent Porphyria ... More >> Hereditary Coproporphyria Variegate Porphyria Less << | Phase 2 | Recruiting | September 2021 | United States, Texas ... More >> University of Texas Medical Branch Recruiting Galveston, Texas, United States, 77555 Contact: Karl E Anderson, MD 409-772-4661 kanderso@utmb.edu Contact: Csilla Hallberg, MD 409-772-4661 ext 24661 ckhallbe@UTMB.EDU Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
1.53mL 0.31mL 0.15mL |
7.67mL 1.53mL 0.77mL |
15.34mL 3.07mL 1.53mL |