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Chemical Structure| 1615678-81-3 Chemical Structure| 1615678-81-3

Structure of 1615678-81-3

Chemical Structure| 1615678-81-3

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Product Details of [ 1615678-81-3 ]

CAS No. :1615678-81-3
Formula : C12H7Cl2IO
M.W : 364.99
SMILES Code : IC1=CC=C(OC2=CC=C(Cl)C=C2)C=C1Cl
MDL No. :N/A

Safety of [ 1615678-81-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 1615678-81-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1615678-81-3 ]

[ 1615678-81-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 106-48-9 ]
  • [ 101335-11-9 ]
  • [ 1615678-81-3 ]
YieldReaction ConditionsOperation in experiment
47% With caesium carbonate; In N,N-dimethyl-formamide; at 95℃; for 16h; To a solution of 2-chloro-4-fluoro-1 -iodo-benzene (9.0 g, 1 eq.) in DMF (46 ml.) was added cesium carbonate (22.8 g, 2 eq) then 4-chlorophenol (4.5 g, 1 eq.). The mixture was heated at 95 C for 16h. After cooling, an aq. solution of ammonium chloride (230ml_) was added, and extracted 3 times with diethylether. The organic phases were combined and washed successive- lywith an aq. solution of ammonium chloride (2x), aq. solution of NaOH (2%), water, then a saturated aq. solution of sodium chloride. The organic phase was dried and evaporated to give after purification on column chromatography on silica gel, 2-chloro-4-(4-chlorophenoxy)-1 -iodo- benzene as an oil (16,7 g, yield=47%).
 

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