[ CAS No. 1703-07-7 ] {[proInfo.proName]}

Name: 1703-07-7|6-Chloro-5-methylpyridazin-3(2H)-one|97%
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Quality Control of [ 1703-07-7 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 1703-07-7 ]

Product Details of [ 1703-07-7 ]

CAS No. :	1703-07-7	MDL No. :	MFCD04971427
Formula :	C₅H₅ClN₂O	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	UGDOVAWXAHZLEV-UHFFFAOYSA-N
M.W :	144.56	Pubchem ID :	164871
Synonyms :

Calculated chemistry of [ 1703-07-7 ]

Physicochemical Properties

Num. heavy atoms :	9
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.2
Num. rotatable bonds :	0
Num. H-bond acceptors :	2.0
Num. H-bond donors :	1.0
Molar Refractivity :	34.83
TPSA :	45.75 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-6.68 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.25
Log Po/w (XLOGP3) :	0.71
Log Po/w (WLOGP) :	0.73
Log Po/w (MLOGP) :	0.79
Log Po/w (SILICOS-IT) :	2.17
Consensus Log Po/w :	1.13

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-1.68
Solubility :	3.04 mg/ml ; 0.021 mol/l
Class :	Very soluble
Log S (Ali) :	-1.25
Solubility :	8.15 mg/ml ; 0.0564 mol/l
Class :	Very soluble
Log S (SILICOS-IT) :	-2.54
Solubility :	0.418 mg/ml ; 0.00289 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	0.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.93

Safety of [ 1703-07-7 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P280-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302-H315-H319-H332-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 1703-07-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 1703-07-7 ]
Downstream synthetic route of [ 1703-07-7 ]

[ 1703-07-7 ] Synthesis Path-Upstream 1~7

1
[ 1703-07-7 ]
[ 54709-94-3 ]

Reference： [1] Pharmaceutical Bulletin, 1957, vol. 5, p. 229,233
[2] Yakugaku Zasshi, 1962, vol. 82, p. 304,307[3] Chem.Abstr., 1963, vol. 58, # 3427,

2
[ 19064-64-3 ]
[ 1834-27-1 ]
[ 1703-07-7 ]

Yield	Reaction Conditions	Operation in experiment
18%	Stage #1: at 110 - 115℃; for 3 h; Stage #2: With sodium hydrogencarbonate In water	3,6-Dichloro-4-methylpyridazine (30.6 g, 190 mmol) was suspended in glacial AcOH (800 mL) at ambient temperature and heated in an oil bath thermostatted at 110-115 °C for 3 h. (The mixture became homogenous after 1 h.) The mixture was allowed to cool and the AcOH was removed by vacuum distillation. The resulting solid residue was slowly treated with sat. NaHCO₃ solution (200 mL) to give a pale yellow heterogenous mixture that was adjusted to pH 6 by the slow addition of solid NaHCO₃ with vigorous stirring. The mixture was extracted with dichloromethane (2 x 250 mL) and the combined organic phase was washed with sat. NaCl solution (60 mL), dried (MgSO₄) and evaporated to afford a solid (20.9 g). The crude material was subjected to column chromatography (gradient 1percent MeOH/CH₂Cl₂ to 5percent MeOH/CH₂Cl₂) to afford, 6-chloro-4-methyl-2H-pyridazin-3-one (13.4 g, 92.7 mmol; 49percent) [R_f 0.21 (2.5percent MeOH/CH₂Cl₂)] and 6-chloro-5-methyl-2H-pyridazin-3-one (5.00 g, 34.6 mmol; 18percent) [R_f 0.11 (2.5percent MeOH/CH₂Cl₂)] as a colourless solids. 6-Chloro-4-methyl-2H-pyridazin-3-one: ¹H NMR (200 MHz, CDCl₃-CD₃OD): 2.12 (3H, s), 3.55 (1H, brs), 7.05 (1H, s); ¹³C NMR (50 MHz, CDCl₃): 16.1 (CH₃), 131.7 (CH-5), 139.0 (C-6), 143.0 (C-4), 161.9 (C-3). 6-Chloro-5-methyl-2H-pyridazin-3-one: mp 172-173 °C (from CH₂Cl₂/light petrol); ¹H NMR (200 MHz, CDCl₃) δ 2.20 (3H, d, J = 1.3 Hz), 7.13 (1H, q, J = 1.3 Hz); ¹³C NMR (50 MHz, CDCl₃) 16.3 (CH₃), 131.9 (CH-5), 139.2 (C-4), 143.2 (C-6), 161.9 (C-3). LRMS (EI): 144 ([M⁺]). Anal. calcd for C₅H₅ClN₂O: C, 41.54; H, 3.49; N, 19.38. Found: C, 41.55; H, 3.51; N, 19.22.
46%	Stage #1: for 2 h; Reflux Stage #2: With acetic acid In water	Intermediate VII6-Chloro-4-methyl-2H-pyridazin-3-one and 6-chloro-5-methyl-2H-pyridazin-3-one A suspension of 3,6-dichloro-4-methylpyridazine (6.60 g) in 3.3 M aqueous NaOH solution (66 mL) was stirred at reflux temperature for 2 h. The heating bath was removed and 50percent aqueous acetic acid (25 mL) was added. The aqueous solution was adjusted to pH value 6 and the precipitate formed thereafter was separated by filtration and washed with little water. The precipitate was chromatographed on silica gel (cyclohexane/ethyl acetate 90:10->0:100) to separate the two title compounds.6-Chloro-4-methyl-2H-pyridazin-3-one: Yield: 2.70 g (46percent of theory). Mass spectrum (ESI⁺): m/z=145/147 (Cl) [M+H]⁺. ¹H NMR (400 MHz, DMSO-d₆) δ 2.06 (d, J=1.3 Hz, 3H), 7.44 (incompletely resolved q, J=1.3 Hz, 1H), 13.03 (broad s, 1H).6-Chloro-5-methyl-2H-pyridazin-3-one: Yield: 1.90 g (32percent of theory). Mass spectrum (ESI⁺): m/z=145/147 (Cl) [M+H]⁺. ¹H NMR (400 MHz, DMSO-d₆) δ 2.19 (d, J=1.3 Hz, 3H), 6.91 (incompletely resolved q, J=1.3 Hz, 1H), 13.02 (broad s, 1H).

Reference： [1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 5, p. 1644 - 1658
[2] Patent: US2012/108578, 2012, A1, . Location in patent: Page/Page column 26
[3] Acta Chemica Scandinavica (1947-1973), 1961, vol. 15, p. 1660,1665
[4] Pharmaceutical Bulletin, 1957, vol. 6, p. 587,589
[5] Pharmaceutical Bulletin, 1957, vol. 5, p. 229,233

3
[ 19064-64-3 ]
[ 1834-27-1 ]
[ 1703-07-7 ]

Yield	Reaction Conditions	Operation in experiment
18%	Stage #1: at 110 - 115℃; for 3 h; Stage #2: With sodium hydrogencarbonate In water	3,6-Dichloro-4-methylpyridazine (30.6 g, 190 mmol) was suspended in glacial AcOH (800 mL) at ambient temperature and heated in an oil bath thermostatted at 110-115 °C for 3 h. (The mixture became homogenous after 1 h.) The mixture was allowed to cool and the AcOH was removed by vacuum distillation. The resulting solid residue was slowly treated with sat. NaHCO₃ solution (200 mL) to give a pale yellow heterogenous mixture that was adjusted to pH 6 by the slow addition of solid NaHCO₃ with vigorous stirring. The mixture was extracted with dichloromethane (2 x 250 mL) and the combined organic phase was washed with sat. NaCl solution (60 mL), dried (MgSO₄) and evaporated to afford a solid (20.9 g). The crude material was subjected to column chromatography (gradient 1percent MeOH/CH₂Cl₂ to 5percent MeOH/CH₂Cl₂) to afford, 6-chloro-4-methyl-2H-pyridazin-3-one (13.4 g, 92.7 mmol; 49percent) [R_f 0.21 (2.5percent MeOH/CH₂Cl₂)] and 6-chloro-5-methyl-2H-pyridazin-3-one (5.00 g, 34.6 mmol; 18percent) [R_f 0.11 (2.5percent MeOH/CH₂Cl₂)] as a colourless solids. 6-Chloro-4-methyl-2H-pyridazin-3-one: ¹H NMR (200 MHz, CDCl₃-CD₃OD): 2.12 (3H, s), 3.55 (1H, brs), 7.05 (1H, s); ¹³C NMR (50 MHz, CDCl₃): 16.1 (CH₃), 131.7 (CH-5), 139.0 (C-6), 143.0 (C-4), 161.9 (C-3). 6-Chloro-5-methyl-2H-pyridazin-3-one: mp 172-173 °C (from CH₂Cl₂/light petrol); ¹H NMR (200 MHz, CDCl₃) δ 2.20 (3H, d, J = 1.3 Hz), 7.13 (1H, q, J = 1.3 Hz); ¹³C NMR (50 MHz, CDCl₃) 16.3 (CH₃), 131.9 (CH-5), 139.2 (C-4), 143.2 (C-6), 161.9 (C-3). LRMS (EI): 144 ([M⁺]). Anal. calcd for C₅H₅ClN₂O: C, 41.54; H, 3.49; N, 19.38. Found: C, 41.55; H, 3.51; N, 19.22.
46%	Stage #1: for 2 h; Reflux Stage #2: With acetic acid In water	Intermediate VII6-Chloro-4-methyl-2H-pyridazin-3-one and 6-chloro-5-methyl-2H-pyridazin-3-one A suspension of 3,6-dichloro-4-methylpyridazine (6.60 g) in 3.3 M aqueous NaOH solution (66 mL) was stirred at reflux temperature for 2 h. The heating bath was removed and 50percent aqueous acetic acid (25 mL) was added. The aqueous solution was adjusted to pH value 6 and the precipitate formed thereafter was separated by filtration and washed with little water. The precipitate was chromatographed on silica gel (cyclohexane/ethyl acetate 90:10->0:100) to separate the two title compounds.6-Chloro-4-methyl-2H-pyridazin-3-one: Yield: 2.70 g (46percent of theory). Mass spectrum (ESI⁺): m/z=145/147 (Cl) [M+H]⁺. ¹H NMR (400 MHz, DMSO-d₆) δ 2.06 (d, J=1.3 Hz, 3H), 7.44 (incompletely resolved q, J=1.3 Hz, 1H), 13.03 (broad s, 1H).6-Chloro-5-methyl-2H-pyridazin-3-one: Yield: 1.90 g (32percent of theory). Mass spectrum (ESI⁺): m/z=145/147 (Cl) [M+H]⁺. ¹H NMR (400 MHz, DMSO-d₆) δ 2.19 (d, J=1.3 Hz, 3H), 6.91 (incompletely resolved q, J=1.3 Hz, 1H), 13.02 (broad s, 1H).

4
[ 19064-64-3 ]
[ 1703-07-7 ]

Reference： [1] Yakugaku Zasshi, 1962, vol. 82, p. 304,307[2] Chem.Abstr., 1963, vol. 58, # 3427,
[3] Yakugaku Zasshi, 1962, vol. 82, p. 1005,1009[4] Chem.Abstr., 1963, vol. 58, # 4559,
[5] Patent: EP2168959, 2010, A1, . Location in patent: Page/Page column 112
[6] Patent: US2008/207902, 2008, A1, . Location in patent: Page/Page column 62

5
[ 89466-36-4 ]
[ 1703-07-7 ]

Reference： [1] Yakugaku Zasshi, 1962, vol. 82, p. 1005,1009[2] Chem.Abstr., 1963, vol. 58, # 4559,
[3] Yakugaku Zasshi, 1962, vol. 82, p. 304,307[4] Chem.Abstr., 1963, vol. 58, # 3427,

6
[ 616-02-4 ]
[ 1703-07-7 ]

Reference： [1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 5, p. 1644 - 1658

7
[ 5754-18-7 ]
[ 1703-07-7 ]

Reference： [1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 5, p. 1644 - 1658

[ 1703-07-7 ] Synthesis Path-Downstream 1~5

1
[ 19064-64-3 ]
[ 1834-27-1 ]
[ 1703-07-7 ]

Yield	Reaction Conditions	Operation in experiment
49%; 18%		3,6-Dichloro-4-methylpyridazine (30.6 g, 190 mmol) was suspended in glacial AcOH (800 mL) at ambient temperature and heated in an oil bath thermostatted at 110-115 C for 3 h. (The mixture became homogenous after 1 h.) The mixture was allowed to cool and the AcOH was removed by vacuum distillation. The resulting solid residue was slowly treated with sat. NaHCO3 solution (200 mL) to give a pale yellow heterogenous mixture that was adjusted to pH 6 by the slow addition of solid NaHCO3 with vigorous stirring. The mixture was extracted with dichloromethane (2 x 250 mL) and the combined organic phase was washed with sat. NaCl solution (60 mL), dried (MgSO4) and evaporated to afford a solid (20.9 g). The crude material was subjected to column chromatography (gradient 1% MeOH/CH2Cl2 to 5% MeOH/CH2Cl2) to afford, 6-chloro-4-methyl-2H-pyridazin-3-one (13.4 g, 92.7 mmol; 49%) [Rf 0.21 (2.5% MeOH/CH2Cl2)] and 6-chloro-5-methyl-2H-pyridazin-3-one (5.00 g, 34.6 mmol; 18%) [Rf 0.11 (2.5% MeOH/CH2Cl2)] as a colourless solids. 6-Chloro-4-methyl-2H-pyridazin-3-one: 1H NMR (200 MHz, CDCl3-CD3OD): 2.12 (3H, s), 3.55 (1H, brs), 7.05 (1H, s); 13C NMR (50 MHz, CDCl3): 16.1 (CH3), 131.7 (CH-5), 139.0 (C-6), 143.0 (C-4), 161.9 (C-3). 6-Chloro-5-methyl-2H-pyridazin-3-one: mp 172-173 C (from CH2Cl2/light petrol); 1H NMR (200 MHz, CDCl3) delta 2.20 (3H, d, J = 1.3 Hz), 7.13 (1H, q, J = 1.3 Hz); 13C NMR (50 MHz, CDCl3) 16.3 (CH3), 131.9 (CH-5), 139.2 (C-4), 143.2 (C-6), 161.9 (C-3). LRMS (EI): 144 ([M+]). Anal. calcd for C5H5ClN2O: C, 41.54; H, 3.49; N, 19.38. Found: C, 41.55; H, 3.51; N, 19.22.
46%; 32%		Intermediate VII6-Chloro-4-methyl-2H-pyridazin-3-one and 6-chloro-5-methyl-2H-pyridazin-3-one A suspension of 3,6-dichloro-4-methylpyridazine (6.60 g) in 3.3 M aqueous NaOH solution (66 mL) was stirred at reflux temperature for 2 h. The heating bath was removed and 50% aqueous acetic acid (25 mL) was added. The aqueous solution was adjusted to pH value 6 and the precipitate formed thereafter was separated by filtration and washed with little water. The precipitate was chromatographed on silica gel (cyclohexane/ethyl acetate 90:10->0:100) to separate the two title compounds.6-Chloro-4-methyl-2H-pyridazin-3-one: Yield: 2.70 g (46% of theory). Mass spectrum (ESI+): m/z=145/147 (Cl) [M+H]+. 1H NMR (400 MHz, DMSO-d6) delta 2.06 (d, J=1.3 Hz, 3H), 7.44 (incompletely resolved q, J=1.3 Hz, 1H), 13.03 (broad s, 1H).6-Chloro-5-methyl-2H-pyridazin-3-one: Yield: 1.90 g (32% of theory). Mass spectrum (ESI+): m/z=145/147 (Cl) [M+H]+. 1H NMR (400 MHz, DMSO-d6) delta 2.19 (d, J=1.3 Hz, 3H), 6.91 (incompletely resolved q, J=1.3 Hz, 1H), 13.02 (broad s, 1H).

Reference： [1]Bioorganic and Medicinal Chemistry,2012,vol. 20,p. 1644 - 1658
[2]Patent: US2012/108578,2012,A1 .Location in patent: Page/Page column 26
[3]Acta Chemica Scandinavica (1947),1961,vol. 15,p. 1660,1665
[4]Pharmaceutical Bulletin,1957,vol. 6,p. 587,589
[5]Pharmaceutical Bulletin,1957,vol. 5,p. 229,233

2
[ 1703-07-7 ]
[ 54709-94-3 ]

Reference： [1]Pharmaceutical Bulletin,1957,vol. 5,p. 229,233

3
[ 1703-07-7 ]
[ 89283-31-8 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: palladium/charcoal; aqueous NH₃ / Hydrogenation 2: POCl₃

Reference： [1]Takahayashi [Pharmaceutical Bulletin, 1957, vol. 5, p. 229,233]

4
[ 5754-18-7 ]
[ 1703-07-7 ]

Reference： [1]Bioorganic and Medicinal Chemistry,2012,vol. 20,p. 1644 - 1658

5
[ 1703-07-7 ]
[ 877160-63-9 ]
6-(4-amino-2-chlorophenyl)-5-methylpyridazin-3(2H)-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
4.5%	With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium carbonate In water; N,N-dimethyl-formamide at 20 - 100℃; for 16h; Inert atmosphere;

Reference： [1]O'Malley, Daniel P.; Ahuja, Vijay; Fink, Brian; Cao, Carolyn; Wang, Cindy; Swanson, Jesse; Wee, Susan; Gavai, Ashvinikumar V.; Tokarski, John; Critton, David; Paiva, Anthony A.; Johnson, Benjamin M.; Szapiel, Nicolas; Xie, Dianlin [ACS Medicinal Chemistry Letters, 2019, vol. 10, # 10, p. 1486 - 1491]

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P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 1703-07-7 ] {[proInfo.proName]}

Quality Control of [ 1703-07-7 ]

Related Doc. of [ 1703-07-7 ]

Product Details of [ 1703-07-7 ]

Calculated chemistry of [ 1703-07-7 ]

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 1703-07-7 ]

Application In Synthesis of [ 1703-07-7 ]

[ 1703-07-7 ] Synthesis Path-Upstream 1~7

[ 1703-07-7 ] Synthesis Path-Downstream 1~5

Related Functional Groups of [ 1703-07-7 ]

Chlorides

Amides

Related Parent Nucleus of [ 1703-07-7 ]

Pyridazines

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 1703-07-7 ]

Related Parent Nucleus of
[ 1703-07-7 ]