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Chemical Structure| 172468-38-1 Chemical Structure| 172468-38-1

Structure of 172468-38-1

Chemical Structure| 172468-38-1

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Product Details of [ 172468-38-1 ]

CAS No. :172468-38-1
Formula : C6H11N3O2
M.W : 157.17
SMILES Code : [N-]=[N+]=NCCCCOC(C)=O

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Application In Synthesis of [ 172468-38-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 172468-38-1 ]

[ 172468-38-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4224-62-8 ]
  • [ 79598-53-1 ]
  • [ 172468-38-1 ]
YieldReaction ConditionsOperation in experiment
81% With sodium azide; In water; N,N-dimethyl-formamide; Example 1 Synthesis of 4-Azidobutyl Acetate (4.22) To a 500 mL flask was added 5.0 g (33 mmol, 1.0 eq) of 4-chlorobutylacetate and dissolved in 100 mL of DMF. Next 2.6 g (40 mmol, 1.2 eq) of sodium azide was added by a glass pipette. A water condenser was placed onto the flask and the reaction heated to 80° C. for 16 hr with stirring. The reaction was then cooled to room temperature and quenched with 300 mL of water to dissolve the sodium salts. The aqueous solution was extracted with diethyl ether 3*100 mL. The organic layers were combined and dried with MgSO4. The solution was filtered and concentrated under vacuum with no external heat, resulting in 4-azido-1-butylacetate (4.22), which was carried onto the next step without further purification; 1H NMR (CDCl3, 300 MHz): delta: 4.04 (t, J=6.0 Hz, 2H), 3.27 (t, J=6.2 Hz, 2H), 2.00 (s, 3H), 1.76-1.52 (m, 4H). 13C NMR (75 MHz, CDCl3) delta: 170.82, 63.55, 50.84, 25.73, 25.39, 20.73. 81percent yield, clear oil.
 

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