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Chemical Structure| 17412-18-9 Chemical Structure| 17412-18-9

Structure of 17412-18-9

Chemical Structure| 17412-18-9

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Product Details of [ 17412-18-9 ]

CAS No. :17412-18-9
Formula : C8H8ClN3
M.W : 181.62
SMILES Code : CC1=C(C)C(Cl)=NN2C1=NC=C2
MDL No. :MFCD29068335

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Application In Synthesis of [ 17412-18-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17412-18-9 ]

[ 17412-18-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 76593-36-7 ]
  • [ 2032-35-1 ]
  • [ 17412-18-9 ]
YieldReaction ConditionsOperation in experiment
90% With hydrogen bromide; In isopropyl alcohol; for 2.0h;Reflux; Preparation of 6-chloro-7,8-dimethylimidazo[1,2-b]pyridazine To a solution of <strong>[76593-36-7]6-chloro-4,5-dimethylpyridazin-3-amine</strong> (2.00 g, 12.7 mmol, 1.0 equiv) in isopropanol (40 mL) was added bromoacetaldehyde diethyl acetal (5.23 mL, 34.8 mmol, 2.7 equiv), and hydrobromic acid (2.00 mL) and heated to reflux for 2 h. The reaction mixture was diluted with saturated aqueous sodium bicarbonate and extracted with ethyl acetate. Purification by column chromatography using 20% ethyl acetate in hexanes elution gave 2.07 g of the white solid, 90%.
 

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