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Chemical Structure| 1762-34-1 Chemical Structure| 1762-34-1

Structure of Abametapir
CAS No.: 1762-34-1

Chemical Structure| 1762-34-1

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Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases; enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. In vitro and ex vivo research has demonstrated that abametapir not only kills the lice, but also prevents hatching of their eggs. Xeglyze Lotion is emerging as a differentiated development candidate to treat head lice infestations.

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Product Details of Abametapir

CAS No. :1762-34-1
Formula : C12H12N2
M.W : 184.23
SMILES Code : CC1=CN=C(C=C1)C1=NC=C(C)C=C1
MDL No. :MFCD01740554
InChI Key :PTRATZCAGVBFIQ-UHFFFAOYSA-N
Pubchem ID :15664

Safety of Abametapir

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.43mL

1.09mL

0.54mL

27.14mL

5.43mL

2.71mL

54.28mL

10.86mL

5.43mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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