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Chemical Structure| 177167-52-1 Chemical Structure| 177167-52-1

Structure of 177167-52-1

Chemical Structure| 177167-52-1

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Product Details of [ 177167-52-1 ]

CAS No. :177167-52-1
Formula : C7H5Cl2I
M.W : 286.93
SMILES Code : CC1=C(Cl)C=C(I)C=C1Cl

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Application In Synthesis of [ 177167-52-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 177167-52-1 ]

[ 177167-52-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3032-81-3 ]
  • [ 77-78-1 ]
  • [ 177167-52-1 ]
YieldReaction ConditionsOperation in experiment
93% With lithium diisopropyl amide; In tetrahydrofuran; at -78℃; Preparation of 1,3-dichloro-5-iodo-2-methylbenzene To the mixture of LDA (5 mL, 8.6 mmol) in THF (20 mL) was added compound <strong>[3032-81-3]1,3-dichloro-5-iodobenzene</strong> (2.35 g, 8.6 mmol) under -78° C. Then the mixture was added to the pre-cooled solution of (CH3)2SO4 (12 mL, 10.3 mmol) in THF (10 mL) under -78° C. The solution was concentrated under vacuum. The residue was diluted with EA, washed with 1N HCl, 1N NaOH, brine, dried over Na2SO4, concentrated under vacuum to give the desired product (2.3 g, 93percent yield).
 

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