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Chemical Structure| 17903-42-3 Chemical Structure| 17903-42-3

Structure of 17903-42-3

Chemical Structure| 17903-42-3

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Product Details of [ 17903-42-3 ]

CAS No. :17903-42-3
Formula : C10H15BrSi
M.W : 243.22
SMILES Code : C[Si](C)(C1=CC=C(CBr)C=C1)C
MDL No. :MFCD20483504

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Application In Synthesis of [ 17903-42-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17903-42-3 ]

[ 17903-42-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3728-43-6 ]
  • [ 17903-42-3 ]
YieldReaction ConditionsOperation in experiment
65% With N-Bromosuccinimide; 1,1'-azobis(1-cyanocyclohexanenitrile); at 120℃; for 5.5h; N-Bromosuccinimide (NBS) (1.07g, 6.00mmol) was added to a solution of <strong>[3728-43-6]trimethyl(p-tolyl)silane</strong> (986mg, 6.00mmol) in α,α,α-trifluorotoluene (40mL). 1,1′-Azobis(cyclohexanecarbonitril) (ABCN) (15mg, 0.06mmol) was added, and the reaction was stirred at 120C for 5.5h. After cooling to room temperature, the mixture was washed with water (2×20mL). The water phases were back-extracted with diethyl ether (3×15mL). The combined organic phases were dried over Na2SO4. Evaporation of the solvent gave 1.53g of the crude product, which was purified by silica-gel column chromatography (hexane, Rf=0.23). This gave 943mg (3.88mmol, 65%) of clear oil. 1H NMR (CDCl3, 400MHz) δ: 0.26 (s, 9H), 4.49 (s, 2H), 7.36-7.39 (m, 2H), 7.48-7.52 (m, 2H). 1H NMR confirmed with that reported previously[26].
 

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