[ CAS No. 1874-23-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

2D 3D

Structure of 1874-23-3 * Storage: {[proInfo.prStorage]}

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]}	{[ getRatePrice(item.pr_usd, 1,1) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]}	{[ item.pr_usastock ]}	Inquiry -	{[ item.pr_chinastock ]}	Inquiry -

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 110K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 1874-23-3 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 1874-23-3 ]

SDS Specification

Alternatived Products of [ 1874-23-3 ]

Product Details of [ 1874-23-3 ]

CAS No. :	1874-23-3	MDL No. :	MFCD00051956
Formula :	C₆H₅NO₅	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	UTLKCGPAJUYGOM-UHFFFAOYSA-N
M.W :	171.11	Pubchem ID :	94882
Synonyms :

Safety of [ 1874-23-3 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P280-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 1874-23-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 1874-23-3 ]
Downstream synthetic route of [ 1874-23-3 ]

[ 1874-23-3 ] Synthesis Path-Upstream 1~2

1
[ 1874-23-3 ]
[ 78-79-5 ]
[ 82788-37-2 ]
[ 82788-34-9 ]

Reference： [1] Tetrahedron Letters, 2005, vol. 46, # 50, p. 8711 - 8714

2
[ 1874-23-3 ]
[ 824-38-4 ]
[ 2217-65-4 ]

Reference： [1] Journal of Heterocyclic Chemistry, 1981, vol. 18, p. 1241 - 1244

[ 1874-23-3 ] Synthesis Path-Downstream 1~13

1
[ 1874-23-3 ]
[ 93-69-6 ]
[ 100621-57-6 ]

Reference： [1]Sherman,W.R. [Journal of Organic Chemistry, 1961, vol. 26, p. 88 - 95]

2
[ 1874-23-3 ]
[ 5304-59-6 ]
[ 96583-15-2 ]

Reference： [1]Sherman,W.R. [Journal of Organic Chemistry, 1961, vol. 26, p. 88 - 95]

3
[ 1874-23-3 ]
[ 824-38-4 ]
[ 2217-65-4 ]

Reference： [1]Journal of Heterocyclic Chemistry,1981,vol. 18,p. 1241 - 1244

4
[ 611-13-2 ]
[ 1874-23-3 ]

Yield	Reaction Conditions	Operation in experiment
90%		42 ml (0.88 mol) of fuming nitric acid was slowly added to 100 ml of acetic anhydride at -5 C.21.3 ml (0.2 mol) of methyl furoate was dissolved in 35 ml of acetic anhydride and slowly added dropwise at -5 CBetween not less than 30 minutes) fuming nitric acid / acetic anhydride system. The reaction was carried out at -5 C for 2 hoursShould be completed. Then quenched with ice water, extracted with ethyl acetate, the organic layers were combined and the organic layer was washed with saturated carbonic acidSodium hydrogen aqueous solution to neutral, and then washed once with water, anhydrous sodium sulfate drying, spinning to obtain a yellow solid(42 g, yield 92%). The yellow solid was dissolved in methylene chloride and added dropwise at -5 C(0.18 mol) of N, N-diisopropylethylamine. After the addition, the reaction was carried out at room temperature for 2 hours, and the reaction was completed by TLCall. The reaction solution was poured into 18 ml of concentrated hydrochloric acid and 125 g of ice water, extracted with methylene chloride, and the organic layers were combined,The organic layer was washed with a saturated aqueous solution of sodium hydrogencarbonate to a weak acid, washed once with water, dried over anhydrous sodium sulfate,A gray solid was recrystallized from methanol to give 28 g of methyl 5-nitrofuronate as a pale yellow solid (90% yield).
90%		To 100 mL of acetic anhydride at -5C was added 42 mL of fuming nitric acid. To this solution was added 21.3 mL(0.2 mol) of methyl furoate in 35 mL of acetic anhydride at -5C over 2 h. The reaction was stirred at -5oC for 2 hand then quenched with ice water (200 mL). The aqueous layer was extracted with ether (3 × 200 mL), and thecombined ethereal layers were washed with a saturated NaHCO3 solution (300 mL) and water (200 mL), and driedover Na2SO4. After removal of the solvent, the resulting yellow solid (42 g, 92 %) was used in the next stepwithout further purification.To a solution containing 42 g (0.18 mol) of the above solid in 175 mL of CH2Cl2 at -5C was added 31.8 mL (0.18mol) of N, N-diisopropylethylamine. After the addition, the mixture was allowed to warm to r.t., stirred for 15 h,and then poured over 17.5 mL of concentrated HCl and 125 g of ice. The aqueous layer was extracted with CH2Cl2(3 ×200 mL), and the combined organic extracts were washed with a saturated NaHCO3 solution (200 mL), andwater (200 mL), and dried over Na2SO4. Removal of the solvent under reduced pressure left a crude solid that wasdissolved in CH2Cl2 and filtered through a pad of silica gel. After removal of the solvent, the resulting residue wasrecrystallized from methanol to yield the product methyl 5-nitro-furoate as a pale yellow solid (28 g, 90 %). HRMS(ESI): m/z [M + Na]+ calcd for C6H5O5NNa: 194.0065; Found: 194.0054.

Reference： [1]Patent: CN105949213,2016,A .Location in patent: Paragraph 0039; 0040; 0041
[2]Synlett,2017,vol. 28,p. 1187 - 1190
[3]Journal of Heterocyclic Chemistry,1995,vol. 32,p. 1283 - 1287
[4]Journal of Organic Chemistry,1997,vol. 62,p. 4088 - 4096

5
[ 1874-23-3 ]
[ 22600-30-2 ]

Yield	Reaction Conditions	Operation in experiment
	With hydrogen;palladium 10% on activated carbon; In ethyl acetate; at 20℃; under 760.051 Torr; for 2h;	A solution of 100 mg of methyl 5-nitro-2-furoate (Lancaster Synthesis, Windham, N.H., USA) in 20 ml of EtOAc was stirred with 20 mg of Pd/C (10%) under one atmospheric pressure of hydrogen gas. After at RT for 2 hours, the mixture was filtered through a celite pad and concentrated. Pure methyl 5-amino-2-furoate was obtained by purification on a fresh silica gel column eluted with 30% EtOAc in hexane.
4.03 g	With palladium 10% on activated carbon; hydrogen; In ethanol; at 20℃; for 18h;	Pd/C 10% wet (2.5 g) was added to a solution of methyl-5-nitrofuran-2-carboxylate (5 g, 29.2 mmol) in EtOH (50 mL) and the reaction mixture was hydrogenated at rt for 18h under atmospheric pressure. Then the catalyst was filtered off and the filtrate concentrated in vacuum to give a dark red solid (4.03 g, 28.6 mmol). LC (Method F): 1.059 min. LCMS: Anal. Calcd. for C6H7NO3: 141.02, found: 142.04 (M+1)+; 1H NMR (600 MHz, CDCl3) δ ppm 7.03 (d, J= 3.6Hz, 1H), 5.20 (d, J=3.6Hz, 1H), 4.55 (sb, 2H), 3.75 (s, 3H).
	With palladium 10% on activated carbon; hydrogen; In methanol; at 20℃; for 2h;	Dissolve 4-18 (171mg, 1mmol) in methanol (10mL), add Pd/C (10%, 17mg),Place in a hydrogenator to react at room temperature for 2 hours, and TLC (PE:EA=3:1) detects that the reaction is complete.The reaction solution was filtered through Celite, and the filtrate was concentrated to obtain a yellow oil (3-27).

Reference： [1]Organic Letters,2005,vol. 7,p. 5087 - 5090
[2]Synthesis,2006,p. 3316 - 3340
[3]Helvetica Chimica Acta,2002,vol. 85,p. 4485 - 4517
[4]Journal of Heterocyclic Chemistry,1995,vol. 32,p. 1283 - 1287
[5]Advanced Synthesis and Catalysis,2020,vol. 362,p. 314 - 319
[6]Journal of Organic Chemistry,1997,vol. 62,p. 4088 - 4096
[7]Tetrahedron Letters,1996,vol. 37,p. 2903 - 2906
[8]Patent: US2005/256030,2005,A1 .Location in patent: Page/Page column 30
[9]Patent: WO2013/163244,2013,A1 .Location in patent: Paragraph 00260
[10]Patent: CN112107568,2020,A .Location in patent: Paragraph 0317-0320

6
[ 1874-23-3 ]
[ 118-58-1 ]
[ 174276-35-8 ]

Reference： [1]Journal of Heterocyclic Chemistry,2007,vol. 44,p. 1145 - 1148
[2]Chemical and Pharmaceutical Bulletin,1995,vol. 43,p. 2064 - 2067

7
[ 1874-23-3 ]
1-(N-acetyl-N-propylamino)-1,3-butadiene [ No CAS ]
[ 1646-27-1 ]

Reference： [1]Tetrahedron Letters,2005,vol. 46,p. 8711 - 8714

8
[ 1874-23-3 ]
[ 78-79-5 ]
[ 82788-37-2 ]
[ 82788-34-9 ]

Reference： [1]Tetrahedron Letters,2005,vol. 46,p. 8711 - 8714

9
[ 1874-23-3 ]
[ 473733-02-7 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 7 steps 1.1: 86 percent / tBuOK / hexamethylphosphoric acid triamide / 18 h / 20 °C 2.1: 78 percent / nBu₃SnH; AIBN / toluene / 4 h / 90 °C 3.1: 100 percent / LiAlH₄ / tetrahydrofuran / 3 h / 0 - 20 °C 4.1: 78 percent / Dess-Martin periodinane / CH₂Cl₂ / 3 h / 20 °C 5.1: MgSO₄ / CH₂Cl₂ / 48 h / 20 °C 6.1: Et₃N / CH₂Cl₂ 7.1: diethyl ether / -78 - -30 °C 7.2: H₅IO₆; MeNH₂ / methanol; H₂O / 20 °C

Reference： [1]Chao, Jianhua; Taveras, Arthur G.; Chao, Jianping; Aki, Cynthia; Dwyer, Michael; Yu, Younong; Purakkattle, Biju; Rindgen, Diane; Jakway, James; Hipkin, William; Fosetta, James; Fan, Xuedong; Lundell, Daniel; Fine, Jay; Minnicozzi, Michael; Phillips, Jonathan; Merritt, J. Robert [Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 13, p. 3778 - 3783]

10
[ 1874-23-3 ]
[ 3743-23-5 ]
methyl 5-[5-chloro-2-(methyloxy)phenyl]oxy}-2-furancarboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
		60% Sodium hydride (200mg, 5mmol) was added to a stirred solution of 5-chloro-2- methoxyphenol in dimethylformamide (8ml) and the mixture stirred for 10 minutes. Methyl 5-nitro-2-furoate (856mg, 5mmol) was added and the mixture heated at 1200C for 90 minutes then cooled to room temperature and diluted with diethyl ether/water. The organic phase was washed with 2M sodium hydroxide and water (x2), dried (magnesium sulphate) and evaporated to give the title compound as a pale coloured oil (1.19g). LC/MS: Rt=3.10, [MH]+ 283.1

Reference： [1]Patent: WO2006/114272,2006,A1 .Location in patent: Page/Page column 29

11
[ 1874-23-3 ]
[ 7341-24-4 ]
C₁₄H₁₄O₃S [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
67%	With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 80℃; for 3h;	7 General Method of E1 Synthesis 60% NaH (31 mg, 0.78 mmol) dissolved in oil was added to o-tolylmethanethiol (54 mg, 0.39 mmol) solution dissolved in anhydrous DMF (2 mL) at 0° C. and then the solution was left at a room temperature. Methyl 5-nitrofuran-2-carboxylate (67 mg, 0.39 mmol) was added to the reaction mixture and it was stirred at 70° C. for 3 hours. The mixture formed finally was cooled to a room temperature and was cooled down with water, and then was extracted with EtOAc and was washed with NaHCO3(aq.) solution. The organic layer was dried with anhydrous MgSO4 and then was evaporated in vacuo. A preferable product E1 of colorless oil was obtained by column chromatography (EtOAc/Hexane, 1:10).

Reference： [1]Current Patent Assignee: INSTITUT PASTEUR; ST PHARM CO.,LTD. - US2020/31816, 2020, A1 Location in patent: Paragraph 0794; 0795; 0796

12
[ 1874-23-3 ]
[ 2386-57-4 ]
[ 1206969-62-1 ]

Yield	Reaction Conditions	Operation in experiment
30.1%	With copper(l) iodide; In dimethyl sulfoxide; at 100℃; for 6h;Inert atmosphere;	A suspension of methyl 5-nitrofuran-2-carboxylate (1.0 g, 4.9 mmol), sodium methanesulfonate (115 mg, 9.8 mmol) and CuI (139 mg, 7.3 mmol) in DMSO (30 mL) was stirred at 100 C. for 6 hrs under N2 atmosphere. TLC showed the reaction was completed. The mixture was cooled down. The reaction was diluted with EtOAc (30 mL) and quenched with water (70 mL). The mixture was filtered, and the filtrate was extracted with EtOAc (10 mL). The combined organic layers were washed with brine, dried over Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by MPLC to give methyl 5-(methylsulfonyl)furan-2-carboxylate (0.3 g, yield: 30.1%) as brown oil. 1H NMR (400 MHz, CDCl3) delta=7.25 (d, J=3.4 Hz, 1H), 7.22 (d, J=3.4 Hz, 1H), 3.96 (s, 3H), 3.23 (s, 3H).

Reference： [1]Patent: US2020/123117,2020,A1 .Location in patent: Paragraph 1129; 1130

13
[ 1874-23-3 ]
[ 31230-24-7 ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C 2: 1 h / 20 °C

Reference： [1]Current Patent Assignee: PEKING UNIVERSITY - CN112107568, 2020, A

Same Skeleton Products

Related Products

Historical Records

Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 1874-23-3 ] {[proInfo.proName]}

Quality Control of [ 1874-23-3 ]

Related Doc. of [ 1874-23-3 ]

Product Details of [ 1874-23-3 ]

Safety of [ 1874-23-3 ]

Application In Synthesis of [ 1874-23-3 ]

[ 1874-23-3 ] Synthesis Path-Upstream 1~2

[ 1874-23-3 ] Synthesis Path-Downstream 1~13

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry