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Chemical Structure| 190071-23-9 Chemical Structure| 190071-23-9

Structure of 190071-23-9

Chemical Structure| 190071-23-9

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Product Details of [ 190071-23-9 ]

CAS No. :190071-23-9
Formula : C10H10INO3
M.W : 319.10
SMILES Code : O=C(OC)C1=CC=C(NC(C)=O)C(I)=C1
English Name :Methyl 4-acetamido-3-iodobenzoate
MDL No. :MFCD09998274

Safety of [ 190071-23-9 ]

Application In Synthesis of [ 190071-23-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 190071-23-9 ]

[ 190071-23-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6575-25-3 ]
  • [ 190071-23-9 ]
  • [ 1021165-74-1 ]
YieldReaction ConditionsOperation in experiment
With copper(l) iodide; methyl 1-thio-β-D-galactopyranoside In 1,4-dioxane at 100℃; 3-1 To a solution of 4-acetylamino-3-iodo-benzoic acid methyl ester (0.17 g) in TMG (1.5 mL) and dioxane (1.5 mL) were added l,3-dichloro-2-ethynyl-benzene (0.1 g), 10 mol % of Pd(PPh3)2Cl2, and 10 mol % of CuI. The reaction mixture was heated to 100 0C overnight. The solvent were evaporated and the resulting mixture was purified by column chromatography (SiO2, 2:3, EtOAc/Hexane) to give 2-(2,6-dichloro-phenyl)-lH- indole-5-carboxylic acid methyl ester: MS(m/z) 320.0 (M+l).
 

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