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Chemical Structure| 19611-93-9 Chemical Structure| 19611-93-9

Structure of 19611-93-9

Chemical Structure| 19611-93-9

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Product Details of [ 19611-93-9 ]

CAS No. :19611-93-9
Formula : C10H8BrNO
M.W : 238.08
SMILES Code : BrCC(C1=CNC2=C1C=CC=C2)=O
MDL No. :MFCD11182378

Safety of [ 19611-93-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 19611-93-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 19611-93-9 ]

[ 19611-93-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 56354-98-4 ]
  • [ 19611-93-9 ]
  • 3-(2-(1H-indol-3-yl)-2-oxoethyl)-6-aminobenzo[d]thiazol-2(3H)-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
60% General procedure: To a stirred suspension of benzo [d]oxazol-2(3H)-one derivative,or benzimidazole, or 2H-benzo [b] [1,4]oxazin-3(4H)-one(1.0 mmol), anhydrous K2CO3 (1.2 mmol) was added in the DMFsolvent for 20 min at 70 C. Then bromoacetylated 1a-1f or 2a-2c(1.3 mmol) and TBAI (0.1 mmol) were added simultaneously. Thereaction was stirred and heated for 4 h. After completion, themixture was extracted with EtOAc/H2O three times. The combinedorganic layers were washed with brine, dried over anhydrousNa2SO4, filtered and concentrated under reduced pressure. Thecrude product was purified by silica gel column chromatographyeluting with EtOAc/PE (3:1e8:1) to afford compounds B01-B29,C01-C03.
 

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