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Chemical Structure| 6698-26-6 Chemical Structure| 6698-26-6

Structure of 2',5'-Dideoxyadenosine
CAS No.: 6698-26-6

Chemical Structure| 6698-26-6

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2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site with an IC50 of 3 µM . 2',5'-Dideoxyadenosine is a nucleoside analog and exerts a potent antiadrenergic action in heart .

Synonyms: NSC 95943

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Product Details of 2',5'-Dideoxyadenosine

CAS No. :6698-26-6
Formula : C10H13N5O2
M.W : 235.24
SMILES Code : C[C@H]1O[C@H](C[C@@H]1O)N1C=NC2=C1N=CN=C2N
Synonyms :
NSC 95943
MDL No. :MFCD00210904

Safety of 2',5'-Dideoxyadenosine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of 2',5'-Dideoxyadenosine

GPCR

Isoform Comparison

Biological Activity

Description
2',5'-Dideoxyadenosine effectively inhibits adenylyl cyclase in a non-competitive manner by binding to the P-site, with an IC50 of 3 µM. It is a nucleoside analog and exhibits strong antiadrenergic effects in the heart[1][2].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.25mL

0.85mL

0.43mL

21.25mL

4.25mL

2.13mL

42.51mL

8.50mL

4.25mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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