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Chemical Structure| 385-00-2 Chemical Structure| 385-00-2
Chemical Structure| 385-00-2

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Shalihi, Devy Janisca ; Murniati, Neni ; Rahman, Wiguna ; Hutabarat, Prima Wahyu Kusuma ; Lailaty, Intani Quarta ;

Abstract: Rhododendron multicolor Miq. exhibits distinctive morphoanatomical characteristics and various bioactive compounds with medicinal and horticultural potential. Numerous studies indicated Rhododendron species are widely utilized as medicinal and ornamental plants, owing to their diverse phytochemical profiles and distinctive morphoanatomical characteristics. However, comprehensive studies of the morphoanatomy and leaves metabolite profile of R. multicolor are still limited globally, as well as its minimal utilization by local communities, highlighting a significant knowledge gap. Therefore, this study aimed to analyze the morphology, paradermal anatomy, and metabolite profile of young leaves and mature leaves of R. multicolor. Morphoanatomy characteristics were analyzed descriptively, anatomical features were analyzed using specific formulas, and metabolite profiling was analyzed using qualitative phytochemicals and gas chromatography-mass spectrometry (GC-MS). The result shows that R. multicolor is a shrubby plant characterized by funnel-shaped flowers in a vibrant red hue, along with narrowly elliptic, scaly leaves. The scales are stellate lobed irregularly with lower density than stomata; the epidermis is polygonal to irregular that has a higher density compared to stomata. The results of the qualitative phytochemical test of Rhododendron multicolor are that it contains phenols, flavonoids, Mayer alkaloids, Bouchardat alkaloids, Dragendorf alkaloids, tannins, and saponins. Based on GC-MS analysis of young leaves and mature leaves of R. multicolor, a total of 31 metabolite compounds from 21 compound groups were identified, with the major compound being squalene from the terpenoid group, which has the potential to be an antioxidant, anticancer, antibacterial, antifungal, antitumor, and cardioprotective.

Keywords: Morphoanatomy ; metabolite compounds ; Rhododendron multicolor Miq ; Vireya ; Cibodas Botanic Garden

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Marie L. Mortensen ; Shubham Bisht ; Muhammad Abbas ; Hamid Firouzi ; Gregory T. McCandless ; Michael Shatruk , et al.

Abstract: Two fluoro-bridged lanthanide-containing metal–organic frameworks (MOFs) were synthesized using 2,2′-bipyridine-4,4′-dicarboxylic acid (BPDC), a fluorinated modulator, and a lanthanide nitrate. The syntheses of MOFs containing Gd3+ or Tb3+ and a closely related MOF structure containing Ho3+, Gd3+, or Tb3+ are presented. The presence of the fluorinated metal chains in these MOFs is shown through single crystal X-ray diffraction, energy dispersion X-ray spectroscopy, 19F nuclear magnetic resonance, and X-ray photoelectron spectroscopy. Magnetic measurements reveal weak antiferromagnetic exchange between the Ln3+ ions mediated by fluoride anions along the zigzag ladder chains present in the crystal structures of these MOFs.

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Ajoyan, Zvart ;

Abstract: The work described herein explores the field of metal–organic frameworks (MOFs) with a particular emphasis on rare-earth (RE) cluster-based MOFs. MOFs are materials that are of interest due to their permanent porosity, high surface areas, and tunable structures. This thesis focuses on three different MOFs: RE-UiO-66 (UiO = University of Oslo), RE-CU-10 and RE-CU-27 (CU = Concordia University). The synthesis, characterization, and photophysical properties of these MOFs are presented. Chapter 2 explores tuning of the RE-UiO-66 platform by synthesizing and characterizing mono-, bi- and tri-metal RE-UiO-66 analogues where RE = Tb(III), Gd(III), and Eu(III), ultimately leading to the formation of a white light emitting MOF. Furthermore, a study of the photophysical properties of this series of MOFs is conducted and as a proof of concept, Tb:Gd:Eu-UiO-66 is deposited on a UV light emitting diode (LED), leading to a white light emitting diode (WLED). Chapter 3 describes a facile route for modulating the photoluminescent and radioluminescent properties of Tb(III) cluster-based MOFs. By using Tb(III)-cluster nodes as Xray attenuators, and organic linkers with varying excited state energies as sensitizers, MOFs with metal-based, linker-based, and metal+linker-based photo- and radioluminescence are reported.

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Product Details of 2,6-Difluorobenzoic acid

CAS No. :385-00-2
Formula : C7H4F2O2
M.W : 158.10
SMILES Code : O=C(O)C1=C(F)C=CC=C1F
MDL No. :MFCD00002411
InChI Key :ONOTYLMNTZNAQZ-UHFFFAOYSA-N
Pubchem ID :9796

Safety of 2,6-Difluorobenzoic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313

Application In Synthesis of 2,6-Difluorobenzoic acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 385-00-2 ]
  • Downstream synthetic route of [ 385-00-2 ]

[ 385-00-2 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 385-00-2 ]
  • [ 6185-28-0 ]
YieldReaction ConditionsOperation in experiment
100% With sodium hydroxide In ethanol; water at 20℃; for 0.166667 h; Sodium 2,6-difluorobenzoate; To a solution of 2,6-difluorobenzoic acid (1.0Og1 6.3mmol) in EtOH and water (5:1 , 6OmL) was added 1 N aqueous sodium hydroxide solution (6.33mL, 6.3mmol). The reaction mixture was stirred for 10 minutes at room temperature and then solvents were removed in vacuo to yield sodium 2,6-difluorobenzoate (1.22g, 6.3mmol, quantitative) as an off white solid. 1H NMR (DMSO) δ 6.89 (2H, m), 7.15 (1 H, m).
References: [1] Patent: WO2008/139161, 2008, A1, . Location in patent: Page/Page column 89.
 

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