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Chemical Structure| 127607-62-9 Chemical Structure| 127607-62-9
Chemical Structure| 127607-62-9

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Product Details of 2-(1-Trityl-1H-imidazol-4-yl)ethanol

CAS No. :127607-62-9
Formula : C24H22N2O
M.W : 354.44
SMILES Code : OCCC1=CN(C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C=N1
MDL No. :MFCD09926409

Safety of 2-(1-Trityl-1H-imidazol-4-yl)ethanol

Application In Synthesis of 2-(1-Trityl-1H-imidazol-4-yl)ethanol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 127607-62-9 ]

[ 127607-62-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 872-82-2 ]
  • [ 76-83-5 ]
  • [ 127607-62-9 ]
YieldReaction ConditionsOperation in experiment
40% With triethylamine; In N,N-dimethyl-formamide; at 20℃; for 12h; Triphenylmethyl chloride (29.84 g, 107.0 mmol, 1.2 eq) is added at room temperature to a stirred solution of <strong>[872-82-2]2-(1H-imidazol-4-yl)ethanol</strong> (10.0 g, 89.18 mmol, 1.0 eq) [872-82-2] in N,N-dimethylformamide (300 mL), followed by triethylamine (14.92 mL, 107.0 mmol, 1.2 eq). After 12 hours stirring at room temperature, the reaction mixture is poured into crushed ice and the resulting solid is collected by filtration, washed with water and acetone to afford 2-(1-tritylimidazol-4-yl)ethanol as a white solid (12.5 g, 40% yield). 1H-NMR (400 MHz, DMSO-d6) ^ ppm: 7.38 (m, 9H), 7.24 (s, 1H), 7.08 (m, 6H), 6.65 (s, 1H), 4.52 (t, J = 5.6 Hz, 1H), 3.57 (m, 2H), 2.58 (t, J = 7.2 Hz, 2H). MS m/z (+ESI): 355.2 [M+H]+
 

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