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Chemical Structure| 503-87-7 Chemical Structure| 503-87-7
Chemical Structure| 503-87-7

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2-Thiohydantoin is an inhibitor used to prevent corrosion of low-carbon steel, effectively protecting metal surfaces from corrosion damage.

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Product Details of 2-Thiohydantoin

CAS No. :503-87-7
Formula : C3H4N2OS
M.W : 116.14
SMILES Code : S=C(N1)NCC1=O
MDL No. :MFCD00005277
InChI Key :UGWULZWUXSCWPX-UHFFFAOYSA-N
Pubchem ID :1274030

Safety of 2-Thiohydantoin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P301+P312+P330

Application In Synthesis of 2-Thiohydantoin

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 503-87-7 ]

[ 503-87-7 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 503-87-7 ]
  • [ 40359-32-8 ]
  • (Z)-5-[(3-allyloxy)benzylidene]-2-thiohydantoin [ No CAS ]
  • 2
  • [ 503-87-7 ]
  • [ 118289-17-1 ]
  • 5-((2-bromopyridin-4-yl)methylene)-2-thioxoimidazolidin-4-one [ No CAS ]
  • 3
  • [ 503-87-7 ]
  • [ 178546-34-4 ]
  • 5-(3-bromo-5-fluoro-2-hydroxybenzylidene)-2-thioxoimidazolidin-4-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
29% With sodium acetate; In acetic acid; for 12h;Reflux; General procedure: A mixture of compound 20, aldehyde (0.5 mmol, 1 equiv 20), compound 21 (1.2 equiv), and NaOAc (3 equiv) in glacial AcOH (4 mL) was stirred at reflux (12 h) until no starting material remained, assessed by TLC (SiO2, hexane/ethyl acetate, 1:1, v/v). The reaction mixture was cooled down to room temperature, followed by the addition of iced water. The resulting precipitate was filtered and washed successively with water and Et2O (10 mL). The product was subjected to column purification (hexane/ethyl acetate, 0/35%).
  • 4
  • [ 2631-77-8 ]
  • [ 503-87-7 ]
  • 5-(2-hydroxy-3,5-diiodobenzylidene)-2-thioxoimidazolidin-4-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
50% With piperidine; In ethanol; at 80 - 90℃; General procedure: A mixture of aldehyde (0.5 mmol, 1 equiv 20), compound 21 (1.2 equiv), and few drops of piperidine in EtOH (4 mL) was stirred at 80-90C (4-12 h) until no starting material remained, assessed by TLC (SiO2, hexane/ethylacetate, 1:1, v/v). The reaction mixture was cooled down to room temperature. The resulting precipitate was filtered and washed successively with water and Et2O (10 mL).
 

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