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Chemical Structure| 202409-74-3 Chemical Structure| 202409-74-3

Structure of 202409-74-3

Chemical Structure| 202409-74-3

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Product Details of [ 202409-74-3 ]

CAS No. :202409-74-3
Formula : C13H11F3N2O2S
M.W : 316.30
SMILES Code : NC1=NC=C(C(F)(F)F)C=C1C2=CC=C(S(=O)(C)=O)C=C2

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Application In Synthesis of [ 202409-74-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 202409-74-3 ]

[ 202409-74-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 79456-30-7 ]
  • [ 202409-74-3 ]
YieldReaction ConditionsOperation in experiment
A mixture of 2-amino-3-(4-methylthio)phenyl-5-trifluoromethylpyridine (9.7 g), OsO4 (2 mL of a 4% solution in water) and NMO (13 g) in acetone/water (60 mL:5 mL) was stirred at r.t. overnight. Saturated aqueous Na2SO3 was then added and the resulting mixture was stirred for 30 min. The acetone was evaporated and the resulting mixture was extracted with ether and ethyl acetate. The combined organics were washed with Na2SO3, water, brine and then concentrated. The solid residue was stirred vigorously in hexane and ether for 1 h and then filtered to provide the title compound as a pale yellow solid (9.9 g).
 

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