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Chemical Structure| 2031-62-1 Chemical Structure| 2031-62-1

Structure of Methyldiethoxysilane
CAS No.: 2031-62-1

Chemical Structure| 2031-62-1

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Product Details of [ 2031-62-1 ]

CAS No. :2031-62-1
Formula : C5H14O2Si
M.W : 134.25
SMILES Code : C[SiH](OCC)OCC
MDL No. :MFCD00026749
InChI Key :GAURFLBIDLSLQU-UHFFFAOYSA-N
Pubchem ID :6327387

Safety of [ 2031-62-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H315-H319-H335
Precautionary Statements:P210-P261-P305+P351+P338
Class:3
UN#:1993
Packing Group:

Application In Synthesis of [ 2031-62-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 2031-62-1 ]
  • Downstream synthetic route of [ 2031-62-1 ]

[ 2031-62-1 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 2031-62-1 ]
  • [ 1571-08-0 ]
  • [ 146781-28-4 ]
YieldReaction ConditionsOperation in experiment
94%
Stage #1: With dicarbonyl(pentamethylcyclopentadienyl)(4-methoxyphenyl)iron In dichloromethane for 4 h; Inert atmosphere; Irradiation; Schlenk technique
Stage #2: With sodium hydroxide In methanol; waterSchlenk technique; Inert atmosphere
General procedure: In a Schlenk tube under 1 atm of argon, a solution of the substrate (2 mmol, 1 equiv), the precatalyst (0.04 mmol, 0.02 equiv), and the silane (3 mmol, 1.5 equiv) in methylene chloride (15 mL) was irradiated for 4h. After removal of the solvent, methanol (5 mL) and aqueous NaOH solution (2.5 M, 5 mL) were added and the resulting suspension was stirred overnight. Neutralization with aqueous HCl solution (2 M, 30 mL) and brine (20 mL) followed by standard workup gave the desired products as pure yellow oils.
References: [1] Tetrahedron Letters, 2012, vol. 53, # 37, p. 5015 - 5018.
 

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