[ CAS No. 2032-33-9 ] {[proInfo.proName]}

Name: 2032-33-9|N-Benzylpropan-1-amine|97%
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3d Animation Molecule Structure of 2032-33-9

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Quality Control of [ 2032-33-9 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

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Product Details of [ 2032-33-9 ]

CAS No. :	2032-33-9	MDL No. :	MFCD00015197
Formula :	C₁₀H₁₅N	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	OUMBFMLKPJUWDQ-UHFFFAOYSA-N
M.W :	149.23	Pubchem ID :	74850
Synonyms :

Calculated chemistry of [ 2032-33-9 ]

Physicochemical Properties

Num. heavy atoms :	11
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.4
Num. rotatable bonds :	4
Num. H-bond acceptors :	1.0
Num. H-bond donors :	1.0
Molar Refractivity :	48.63
TPSA :	12.03 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	Yes
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	Yes
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-5.63 cm/s

Lipophilicity

Log Po/w (iLOGP) :	2.43
Log Po/w (XLOGP3) :	2.23
Log Po/w (WLOGP) :	2.03
Log Po/w (MLOGP) :	2.49
Log Po/w (SILICOS-IT) :	2.52
Consensus Log Po/w :	2.34

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	2.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-2.31
Solubility :	0.731 mg/ml ; 0.0049 mol/l
Class :	Soluble
Log S (Ali) :	-2.12
Solubility :	1.14 mg/ml ; 0.00762 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-4.03
Solubility :	0.0139 mg/ml ; 0.0000931 mol/l
Class :	Moderately soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	0.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.0

Safety of [ 2032-33-9 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P280	UN#:	N/A
Hazard Statements:	H302+H312+H332	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 2032-33-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 2032-33-9 ]

[ 2032-33-9 ] Synthesis Path-Downstream 1~88

2
[ 74-96-4 ]
[ 2032-33-9 ]
[ 148807-79-8 ]

Reference： [1]Journal of the American Chemical Society,1941,vol. 63,p. 1965

3
[ 64-18-6 ]
[ 2032-33-9 ]
[ 2532-72-1 ]

Reference： [1]Journal of the American Chemical Society,1941,vol. 63,p. 1965

4
[ 79-36-7 ]
[ 2032-33-9 ]
[ 29524-29-6 ]

Reference： [1]Journal of the American Chemical Society,1955,vol. 77,p. 3798,3800

5
[ 6852-55-7 ]
[ 2032-33-9 ]

Reference： [1]Organometallics,2012,vol. 31,p. 5239 - 5242,4
[2]Journal of Organic Chemistry,1984,vol. 49,p. 2021 - 2023
[3]Tetrahedron Letters,1980,vol. 21,p. 3385 - 3388
[4]Bulletin of the Chemical Society of Japan,2003,vol. 76,p. 143 - 151
[5]Monatshefte fur Chemie,2008,vol. 139,p. 117 - 123
[6]Applied Organometallic Chemistry,2013,vol. 27,p. 174 - 176
[7]Advanced Synthesis and Catalysis,2013,vol. 355,p. 1315 - 1322
[8]Journal of the American Chemical Society,1955,vol. 77,p. 3798,3800
[9]Justus Liebigs Annalen der Chemie,1888,vol. 245,p. 285
[10]Journal of Medicinal Chemistry,1984,vol. 27,p. 1111 - 1118
[11]Bulletin of the Chemical Society of Japan,1991,vol. 64,p. 3466 - 3467
[12]Macromolecules,2003,vol. 36,p. 8320 - 8329
[13]Journal of the American Chemical Society,2004,vol. 126,p. 14342 - 14343
[14]Phosphorus, Sulfur and Silicon and the Related Elements,2005,vol. 180,p. 2047 - 2050
[15]Journal of the Chemical Society. Perkin Transactions 1 (2001),2000,p. 3765 - 3774
[16]Food Chemistry,2012,vol. 130,p. 945 - 952
[17]Angewandte Chemie - International Edition,2013,vol. 52,p. 2538 - 2542
Angew. Chem.,2013,vol. 125,p. 2598 - 2602,5
[18]Green Chemistry,2019,vol. 21,p. 2252 - 2256

6
[ 6271-12-1 ]
[ 2032-33-9 ]

Reference： [1]Journal of the American Chemical Society,1927,vol. 49,p. 2908

7
[ 107-10-8 ]
[ 100-39-0 ]
[ 2032-33-9 ]

Reference： [1]Journal of the American Chemical Society,1959,vol. 81,p. 3725,3726

8
[ 2032-33-9 ]
[ 75-03-6 ]
[ 148807-79-8 ]

Reference： [1]Journal of the American Chemical Society,1941,vol. 63,p. 1965

9
[ 2032-33-9 ]
[ 598-31-2 ]
[ 137565-41-4 ]

Reference： [1]Journal of the American Chemical Society,1940,vol. 62,p. 910

10
[ 75-44-5 ]
[ 2032-33-9 ]
[ 55246-49-6 ]

Reference： [1]Bulletin of the Chemical Society of Japan,1977,vol. 50,p. 1872 - 1877
[2]Patent: FR2234293,1975,
Patent: DE2429523,1975,
Chem.Abstr.,1975,vol. 82

11
2-acetamino-5-cyano-benzylbromide [ No CAS ]
[ 2032-33-9 ]
[ 55413-64-4 ]

Yield	Reaction Conditions	Operation in experiment
		EXAMPLE 87 2-Acetamino-N-benzyl-5-cyano-N-n-propyl-benzylamine, m.p. 109-111C, was prepared from 2-acetamino-5-cyano-benzyl bromide and N-n-propyl-benzylamine analogous to Example 25.

Reference： [1]Patent: US3950393,1976,A
[2]Patent: CH609327,1979,
Patent: DE2318636,1974,
Chem.Abstr.,1975,vol. 82

12
[ 2032-33-9 ]
[ 90972-14-8 ]
[ 94436-84-7 ]

Reference： [1]Patent: BE619216,1962,
Chem.Abstr.,1963,vol. 59

13
[ 100368-56-7 ]
[ 2032-33-9 ]

Reference： [1]Chemische Berichte,1961,vol. 94,p. 1879 - 1882

14
[ 107-10-8 ]
[ 100-44-7 ]
[ 2032-33-9 ]

Reference： [1]Journal of the American Chemical Society,1968,vol. 90,p. 3502 - 3506

15
[ 2032-33-9 ]
[ 103-80-0 ]
N-benzyl-2-phenyl-N-propylacetamide [ No CAS ]

Reference： [1]Acta Chemica Scandinavica (1947),1960,vol. 14,p. 1129 - 1150

16
[ 110-87-2 ]
[ 220934-05-4 ]
[ 2032-33-9 ]
[ 99398-29-5 ]
[ 99398-24-0 ]
[ 99398-25-1 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5678 - 5686

17
[ 10400-19-8 ]
[ 2032-33-9 ]
[ 142566-01-6 ]

Reference： [1]Journal of Medicinal Chemistry,1992,vol. 35,p. 2952 - 2958

18
[ 50-00-0 ]
[ 2032-33-9 ]
[ 2532-72-1 ]

Reference： [1]Journal of Medicinal Chemistry,1984,vol. 27,p. 1335 - 1339

19
[ 111-34-2 ]
[ 220934-05-4 ]
[ 2032-33-9 ]
[ 99398-26-2 ]
[ 99398-24-0 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5678 - 5686
[2]Journal of Organic Chemistry,1985,vol. 50,p. 5678 - 5686

20
[ 6651-36-1 ]
[ 220934-05-4 ]
[ 2032-33-9 ]
[ 99398-30-8 ]
[ 99398-25-1 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5678 - 5686

21
[ 32426-80-5 ]
[ 220934-05-4 ]
[ 2032-33-9 ]
[ 99398-31-9 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5678 - 5686

22
[ 32426-79-2 ]
[ 220934-05-4 ]
[ 2032-33-9 ]
[ 99398-32-0 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5678 - 5686

23
[ 1835-02-5 ]
[ 2032-33-9 ]
[ 78095-22-4 ]

Reference： [1]Journal of Medicinal Chemistry,1981,vol. 24,p. 1013 - 1015

24
[ 2532-72-1 ]
[ 2032-33-9 ]

Reference： [1]Journal of the Indian Chemical Society,1985,vol. 62,p. 899 - 903

25
[ 2032-33-9 ]
[ 140715-56-6 ]
2-[3-(Benzyl-propyl-amino)-propyl]-5-nitro-isoindole-1,3-dione [ No CAS ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1991,vol. 39,p. 3225 - 3235

26
[ 2032-33-9 ]
[ 125207-39-8 ]
2-[4-(Benzyl-propyl-amino)-butyl]-5-nitro-isoindole-1,3-dione [ No CAS ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1991,vol. 39,p. 3225 - 3235

27
[ 2032-33-9 ]
[ 133637-47-5 ]
2-[5-(Benzyl-propyl-amino)-pentyl]-5-nitro-isoindole-1,3-dione [ No CAS ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1991,vol. 39,p. 3225 - 3235

28
[ 2032-33-9 ]
[ 84858-19-5 ]
[ 117096-62-5 ]

Reference： [1]Journal of Medicinal Chemistry,1989,vol. 32,p. 183 - 192

29
[ 2032-33-9 ]
[ 10313-60-7 ]
[ 151250-69-0 ]

Reference： [1]Synthetic Communications,1993,vol. 23,p. 1393 - 1402

30
C₂₈H₂₉NP⁽¹⁺⁾*I^(1-) [ No CAS ]
[ 2032-33-9 ]

Reference： [1]Phosphorus, Sulfur and Silicon and the Related Elements,1990,vol. 49/50,p. 151 - 154

31
[ 220934-05-4 ]
[ 2032-33-9 ]
[ 99398-24-0 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5678 - 5686

32
[ 220934-05-4 ]
[ 2032-33-9 ]
[ 99398-25-1 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5678 - 5686

33
[ 107-10-8 ]
[ 100-52-7 ]
[ 2032-33-9 ]

Yield	Reaction Conditions	Operation in experiment
65%		General procedure: The appropriate benzaldehydes (3.33 mmol) was dissolved in anhydrous methanol (20 ml) and cooled to 0 C under stirring. To this cold mixture of n-propylamine (0.39 ml, 6.66 mmol) was added dropwise and stirring was continued for 30 min at 0 C, then for 3 hr at ambient temp. The reaction mixture was again cooled to 0 C and NaBH4 (0.19 g, 5.0 mmol) was added in three portions at 10 min intervals. Then it was stirred at room temp for another 1 hr and the solvent was distilled to 1/3 of its original volume under vacuum. Cold water (5 ml) and NaHCO3 (0.28 g, 3.33 mmol) were added to the above concentrated solution, stirred for 10 min and extracted with methylene chloride (3 x 20 ml). Combined organic phases was dried over Na2SO4 and evaporated the solvent and dried under vacuum to get the compounds (1a-o).
		Add benzaldehyde (1 g, 9.43 mmol) to a 50 mL single-mouth bottle.N-propylamine (1.4 mL, 14.15 mmol),5 mL of methanol and 2 drops of glacial acetic acidAfter stirring at room temperature for half an hour, sodium borohydride (180 mg, 4.74 mmol) was added under ice bath.Stir at room temperature overnight and complete the reaction by TLC.The reaction was quenched with saturated aqueous sodium carbonate and extracted with ethyl acetate.Dry over anhydrous sodium sulfate,Combine the organic solvent and spin dry,Crude product 1.2g,The yield was 84.8%.

Reference： [1]Applied Organometallic Chemistry,2014,vol. 28,p. 113 - 115
[2]Synlett,2006,p. 431 - 434
[3]Bulletin of the Chemical Society of Japan,2003,vol. 76,p. 143 - 151
[4]Synthetic Communications,2008,vol. 38,p. 1976 - 1983
[5]Chinese Journal of Chemistry,2012,vol. 30,p. 1775 - 1780
[6]Organic Process Research and Development,2014,vol. 18,p. 1771 - 1776
[7]Journal of Organic Chemistry,1981,vol. 46,p. 3571 - 3574
[8]Journal of the American Chemical Society,2016,vol. 138,p. 10356 - 10364
[9]Tetrahedron,2004,vol. 60,p. 7899 - 7906
[10]Indian Journal of Heterocyclic Chemistry,2014,vol. 24,p. 115 - 118
[11]Journal of Organic Chemistry,1981,vol. 46,p. 3571 - 3574
[12]Synthesis,2000,p. 789 - 800
[13]Synthetic Communications,1993,vol. 23,p. 1393 - 1402
[14]Journal of the American Chemical Society,1999,vol. 121,p. 7933 - 7934
[15]Patent: CN109206346,2019,A .Location in patent: Paragraph 0320; 0323; 324; 0325

34
[ 2032-33-9 ]
[ 5332-06-9 ]
[ 89690-07-3 ]

Reference： [1]Journal of Organic Chemistry,1984,vol. 49,p. 2021 - 2023

35
[ 2032-33-9 ]
[ 528-76-7 ]
[ 32895-39-9 ]

Reference： [1]Journal of Pharmaceutical Sciences,1971,vol. 60,p. 803 - 805

36
[ 2032-33-9 ]
[ 101566-00-1 ]
[ 172328-06-2 ]

Reference： [1]Bulletin de la Societe Chimique de France,1995,vol. 132,p. 669 - 674
[2]Monatshefte fur Chemie,2014,vol. 145,p. 1139 - 1144

37
[ 10546-70-0 ]
[ 2032-33-9 ]

Reference： [1]European Journal of Medicinal Chemistry,1995,vol. 30,p. 973 - 982
[2]European Journal of Organic Chemistry,2014,vol. 2014,p. 5144 - 5148

38
[ 2032-33-9 ]
(4-Chloro-6-methyl-[1,3,5]triazin-2-yl)-(2,6-dimethyl-phenyl)-amine [ No CAS ]
N-Benzyl-N'-(2,6-dimethyl-phenyl)-6-methyl-N-propyl-[1,3,5]triazine-2,4-diamine [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 4354 - 4357

39
[ 2032-33-9 ]
[ 184021-48-5 ]
N-Benzyl-6-methyl-N-propyl-N'-(2,4,6-trimethyl-phenyl)-[1,3,5]triazine-2,4-diamine [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 4354 - 4357

40
[ 2032-33-9 ]
(4-Chloro-6-methyl-[1,3,5]triazin-2-yl)-(2,6-diethyl-phenyl)-amine [ No CAS ]
N-Benzyl-N'-(2,6-diethyl-phenyl)-6-methyl-N-propyl-[1,3,5]triazine-2,4-diamine [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 4354 - 4357

41
[ 2032-33-9 ]
[ 54871-31-7 ]
N-Benzyl-6-methyl-N-propyl-N'-p-tolyl-[1,3,5]triazine-2,4-diamine [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 4354 - 4357

42
[ 107-20-0 ]
[ 2032-33-9 ]
[ 767576-84-1 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1997,vol. 45,p. 996 - 1007

43
[ 27845-48-3 ]
[ 2032-33-9 ]

Reference： [1]Tetrahedron Letters,1997,vol. 38,p. 7487 - 7490
[2]Tetrahedron Letters,2005,vol. 46,p. 1667 - 1669

44
[ 2032-33-9 ]
[ 182251-52-1 ]
[ 1053611-61-2 ]

Reference： [1]Journal of Medicinal Chemistry,1998,vol. 41,p. 787 - 797

45
[ 2032-33-9 ]
[ 200292-45-1 ]
Benzyl-(2-butyl-thieno[3,2-d]pyrimidin-4-yl)-propyl-amine [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1998,vol. 41,p. 4021 - 4035

46
[ 107-08-4 ]
[ 100-46-9 ]
[ 2032-33-9 ]

Reference： [1]Bulletin of the Chemical Society of Japan,1998,vol. 71,p. 1973 - 1991

47
[ 75-15-0 ]
[ 2032-33-9 ]
[ 74-88-4 ]
Benzyl-propyl-dithiocarbamic acid methyl ester [ No CAS ]

Reference： [1]Bulletin of the Chemical Society of Japan,1998,vol. 71,p. 1973 - 1991

48
[ 71-23-8 ]
[ 100-46-9 ]
[ 20441-12-7 ]
[ 2032-33-9 ]

Reference： [1]Tetrahedron Letters,1999,vol. 40,p. 3689 - 3592

49
[ 4449-98-3 ]
[ 100-52-7 ]
[ 2032-33-9 ]

Reference： [1]Synlett,2000,p. 556 - 558

51
benzaldehyde propylimine [ No CAS ]
[ 2032-33-9 ]

Reference： [1]Journal of the American Chemical Society,1940,vol. 62,p. 910

52
[ 1074-42-6 ]
(CH₃)2CuLi [ No CAS ]
[ 2032-33-9 ]

Reference： [1]Tetrahedron Letters,1985,vol. 26,p. 1153 - 1156

53
[ 2032-33-9 ]
2-bromo-1-<3.4-dibenzyloxy-phenyl>-propanone-(1) [ No CAS ]
(1RS:2SR)-2-propylamino-1-(3.4-dihydroxy-phenyl)-propanol-⁽¹⁾ [ No CAS ]

Reference： [1]Patent: US2151459,1936,
[2]Patent: DE677127,1934,
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 23,p. 495

54
[ 79218-15-8 ]
[ 2032-33-9 ]
[ 265669-75-8 ]

Reference： [1]Journal of the Chemical Society. Perkin Transactions 1 (2001),2000,p. 3765 - 3774

55
[ 22014-89-7 ]
[ 2032-33-9 ]

Reference： [1]Journal of the Chemical Society. Perkin Transactions 1 (2001),2000,p. 3765 - 3774

56
[ 2032-33-9 ]
2-tert-butoxycarbonyloxycarbonyl-piperidine-1-carboxylic acid tert-butyl ester [ No CAS ]
[ 528597-90-2 ]

Reference： [1]Tetrahedron,2003,vol. 59,p. 781 - 787

57
[ 2032-33-9 ]
[ 215115-08-5 ]
benzyl-[8-(2,4-dichloro-phenyl)-2-methyl-quinolin-4-yl]-propyl-amine [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2003,vol. 13,p. 3375 - 3379

58
[ 2032-33-9 ]
[ 204062-61-3 ]
benzyl-[2-methyl-8-(2,4,6-trimethyl-phenyl)-quinolin-4-yl]-propyl-amine [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2003,vol. 13,p. 3375 - 3379

59
[ 2032-33-9 ]
[ 1514-50-7 ]
3-benzyl-1-(4-iodophenyl)-3-propyltriazene [ No CAS ]

Reference： [1]Helvetica Chimica Acta,2004,vol. 87,p. 698 - 718

60
[ 2032-33-9 ]
[ 195055-65-3 ]
benzyl-[3-(6-dimethylamino-4-methyl-pyridin-3-yl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-propyl-amine [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,2004,vol. 47,p. 4787 - 4798

61
[ 2032-33-9 ]
[ 744210-18-2 ]
benzyl-[3-(3-chloro-5-trifluoromethyl-pyridin-2-yl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-propyl-amine [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,p. 3943 - 3947

62
[ 50-00-0 ]
[ 2032-33-9 ]
[ 105-67-9 ]
N-benzyl-N-(3,5-dimethyl-2-hydroxybenzyl)-n-propylamine [ No CAS ]

Reference： [1]Macromolecules,2003,vol. 36,p. 8320 - 8329

63
[ 201230-82-2 ]
[ 2032-33-9 ]
[ 61214-23-1 ]

Reference： [1]Journal of the American Chemical Society,2004,vol. 126,p. 14342 - 14343
[2]Journal of Organic Chemistry,2006,vol. 71,p. 5951 - 5958

64
[ 2032-33-9 ]
[ 405878-88-8 ]
{5-[(Benzyl-propyl-amino)-methyl]-4-trifluoromethyl-thiazol-2-yl}-(2,4,6-trichloro-phenyl)-amine [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2005,vol. 15,p. 431 - 434

65
[ 2032-33-9 ]
[ 6852-55-7 ]

Reference： [1]Synthetic Communications,2005,vol. 35,p. 1989 - 1995

66
[ 444325-42-2 ]
[ 2032-33-9 ]
2-ethyl-7-(2,4,6-trimethyl-phenyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid benzyl-propyl-amide [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2005,vol. 15,p. 3870 - 3873

67
[ 444336-02-1 ]
[ 2032-33-9 ]
benzyl-propyl-[2-trifluoromethyl-8-(2,4,6-trimethyl-phenyl)-8H-1,3a,8-triaza-cyclopenta[a]inden-3-ylmethyl]-amine [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2005,vol. 15,p. 4029 - 4032

68
[ 444326-03-8 ]
[ 2032-33-9 ]
2-trifluoromethyl-8-(2,4,6-trimethyl-phenyl)-8H-1,3a,8-triaza-cyclopenta[a]indene-3-carboxylic acid benzyl-propyl-amide [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2005,vol. 15,p. 4029 - 4032

69
[ 123-38-6 ]
[ 100-46-9 ]
[ 2032-33-9 ]

Reference： [1]Tetrahedron,2005,vol. 61,p. 6988 - 6992

70
[ 123-38-6 ]
[ 932-90-1 ]
[ 20441-12-7 ]
[ 2032-33-9 ]
[ 103-49-1 ]

Reference： [1]Russian Journal of General Chemistry,2004,vol. 74,p. 379 - 383

71
[ 444326-22-1 ]
[ 2032-33-9 ]
benzyl-[8-(2-chloro-4,6-dimethyl-phenyl)-2-methyl-8H-1,3a,7,8-tetraaza-cyclopenta[a]inden-3-ylmethyl]-propyl-amine [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,p. 2026 - 2030

72
[ 2032-33-9 ]
benzyl-propyl-[2-trifluoromethyl-8-(2,4,6-trimethyl-phenyl)-8H-1,3a,8-triaza-cyclopenta[a]inden-3-ylmethyl]-amine [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2005,vol. 15,p. 4029 - 4032

73
[ 620-40-6 ]
[ 2032-33-9 ]

Reference： [1]Journal of the Chemical Society. Perkin Transactions 1 (2001),2000,p. 3765 - 3774

74
[ 103-49-1 ]
[ 2032-33-9 ]

Reference： [1]Journal of the Chemical Society. Perkin Transactions 1 (2001),2000,p. 3765 - 3774

75
[ 2032-33-9 ]
Benzyl-propyl-trifluoromethyl-amine [ No CAS ]

Reference： [1]Bulletin of the Chemical Society of Japan,1998,vol. 71,p. 1973 - 1991

76
[ 2032-33-9 ]
[ 193158-10-0 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1997,vol. 45,p. 996 - 1007

77
[ 2032-33-9 ]
N-[2-(Benzyl-propyl-amino)-ethyl]-N-ethyl-4-oxo-4-(6-oxo-5,6-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-11-yl)-butyramide [ No CAS ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1997,vol. 45,p. 996 - 1007

78
[ 2032-33-9 ]
4-(3,4-Dimethoxy-phenyl)-2-propyl-1,4-dihydro-2H-isoquinolin-3-one [ No CAS ]

Reference： [1]Synthetic Communications,1993,vol. 23,p. 1393 - 1402
[2]Synthetic Communications,1993,vol. 23,p. 1393 - 1402

79
[ 2032-33-9 ]
[ 151250-71-4 ]

Reference： [1]Synthetic Communications,1993,vol. 23,p. 1393 - 1402

80
[ 1576-37-0 ]
[ 2032-33-9 ]

Reference： [1]Journal of the American Chemical Society,1927,vol. 49,p. 2908

81
[ 2032-33-9 ]
4-ethoxy-3-nitro-benzoic acid-[2-(benzyl-propyl-amino)-ethyl ester] [ No CAS ]

Reference： [1]Journal of the American Chemical Society,1958,vol. 80,p. 4320,4323

82
[ 2032-33-9 ]
[ 95228-22-1 ]

Reference： [1]Acta Chemica Scandinavica (1947),1960,vol. 14,p. 1129 - 1150

83
[ 2032-33-9 ]
[ 97082-57-0 ]

Reference： [1]Acta Chemica Scandinavica (1947),1960,vol. 14,p. 1129 - 1150

84
[ 2032-33-9 ]
[ 95744-52-8 ]

Reference： [1]Acta Chemica Scandinavica (1947),1960,vol. 14,p. 1129 - 1150

85
[ 71-43-2 ]
(+-)-pentane-1,4-diol [ No CAS ]
[ 2032-33-9 ]

Reference： [1]Chemische Berichte,1961,vol. 94,p. 1879 - 1882

86
[ 373354-56-4 ]
[ 2032-33-9 ]
C₂₃H₂₂N₂O₃S [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
		Following the procedure of Example 74 using 5,5-Dioxo-2-(4-nitrobenzoxy-carbonylamino)dibenzothiophene (Example 24) and the appropriate amine the following compounds were prepared.

Reference： [1]Patent: US2003/225097,2003,A1 .Location in patent: Page 34,47

87
[ 107-10-8 ]
3-(N-benzyl-N-propylamino)-propionic acid [ No CAS ]
[ 2032-33-9 ]

Yield	Reaction Conditions	Operation in experiment
	With benzaldehyde;palladium;	EXAMPLE 14 3-(N-Benzyl-N-propylamino)-propane-1-hydroxy-1,1-diphosphonic acid Analogously to Example 3, from 3-(N-benzyl-N-propylamino)-propionic acid there is obtained the desired compound in a yield of 35% of theory; m.p. 112-115 C. (decomp.); Mrel =0.33. The starting material is obtained as follows: The oily Schiff base from propylamine and benzaldehyde (yield 86% of theory) is hydrogenated in the presence of palladium catalyst and gives N-benzyl-N-propylamine in a yield of 81% of theory.

Reference： [1]Patent: US4927814,1990,A

88
[ 2032-33-9 ]
[ 28188-41-2 ]
[ 55413-64-4 ]

Yield	Reaction Conditions	Operation in experiment
		EXAMPLE 59 2-Acetamino-N-benzyl-5-cyano-N-n-propyl-benzylamine, m.p. 109-111 C, was prepared from 2-acetamino:5-cyano-benzylbromide and N-n-propyl-benzylamine analogous to Example 8.

Reference： [1]Patent: US4101671,1978,A

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P378
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{[ item.p_purity ]}	{[ item.pr_size ]}	{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]}	{[ getRatePrice(item.pr_usd, 1,1) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]}	{[ item.pr_usastock ]}	Inquiry -	{[ item.pr_chinastock ]}	Inquiry -

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H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
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H221	Flammable gas
H222	Extremely flammable aerosol
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H261	In contact with water releases flammable gas
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Health hazards
Code	Phrase
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H301	Toxic if swallowed
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H303	May be harmful if swallowed
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H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
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H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
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H361d	Suspected of damaging the unborn child
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H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 2032-33-9 ] {[proInfo.proName]}

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[ 2032-33-9 ] Synthesis Path-Downstream 1~88

Pharmaceutical Intermediates of [ 2032-33-9 ]

Rotigotine Intermediates

Rotigotine Intermediates

Related Functional Groups of [ 2032-33-9 ]

Aryls

Amines

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[ 2032-33-9 ]

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[ 2032-33-9 ]