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Chemical Structure| 2039-76-1 Chemical Structure| 2039-76-1

Structure of 3-Acetylphenanthrene
CAS No.: 2039-76-1

Chemical Structure| 2039-76-1

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Product Details of [ 2039-76-1 ]

CAS No. :2039-76-1
Formula : C16H12O
M.W : 220.27
SMILES Code : CC(=O)C1=CC2=C(C=C1)C=CC1=C2C=CC=C1
MDL No. :MFCD00001169
InChI Key :JKVNPRNAHRHQDD-UHFFFAOYSA-N
Pubchem ID :74867

Safety of [ 2039-76-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 2039-76-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2039-76-1 ]

[ 2039-76-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2039-76-1 ]
  • [ 1892-54-2 ]
YieldReaction ConditionsOperation in experiment
81% With pyridine; hydroxylamine hydrochloride; In ethanol; at 75℃; for 1h; 50g (227 mmol) of 3-acetyl-phenanthrene and, pyridine of 63.8ml (7 90 mmol), and hydroxylammonium chloride of 42g (592 mmol) 30 It is dissolved in EtOH of 0 ml. Heating the batch to 75 C. After 1 hour of reaction, to cool the batch. The mixture is then partitioned between ethyl acetate and water, the organic phase is washed three times with water, dried over Na2SO4, is concentrated in a rotary evaporator. 300ml of polyphosphoric acid carefully added dropwise to the concentrated solution, and the mixture is heated for 1 hour at 75C. . It is then batchThen cooled to room temperature, carefully pour the ice water (300ml). The precipitated solid was filtered off with suction, rinsed with methanol. Finally, the addition of concentrated HCL of 800ml of MeOH and 70ml in solids. The reaction mixture for 8 hours, and heated at the boil. Thereafter, the mixture was neutralized using sodium hydroxide solution, partitioned between ethyl acetate and water, the organic phase is washed three times with water, dried over Na2SO4, evaporated in a rotary evaporator. The residue was dried at 40C. in a vacuum. Some in a yield of 35.5g (184 mmol) (81% of theory)
 

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