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[ CAS No. 20632-12-6 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 20632-12-6
Chemical Structure| 20632-12-6
Structure of 20632-12-6 *Storage: {[proInfo.prStorage]}

Quality Control of [ 20632-12-6 ]

Purity: {[proInfo.showProBatch.pb_purity]}

Related Doc. of [ 20632-12-6 ]

SDS

Product Details of [ 20632-12-6 ]

CAS No. :20632-12-6MDL No. :MFCD00859367
Formula :C11H12O3Boiling Point :-
Linear Structure Formula :-InChI Key :N/A
M.W :192.21Pubchem ID :3702569
Synonyms :

Computed Properties of [ 20632-12-6 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 20632-12-6 ]

Signal Word:WarningClassN/A
Precautionary Statements:P261-P305 P351 P338UN#:N/A
Hazard Statements:H302-H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 20632-12-6 ]

  • Downstream synthetic route of [ 20632-12-6 ]

[ 20632-12-6 ] Synthesis Path-Downstream   1~10

  • 2
  • [ 20632-12-6 ]
  • C13H14N2O2 [ No CAS ]
  • 3
  • [ 20632-12-6 ]
  • 6-propyl-1,4-benzodioxane [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium hydrogen sulfate; hydrogen; In isopropyl alcohol; at 110℃; under 5171.62 Torr;Autoclave; General procedure: 122 g of 1,3-benzodioxole and 150 g of ethylene dichloride were charged into a 1 litre reaction flask and the mixture was cooled to 0C under stirring followed by the addition of 44.5 g of Zinc oxide under stirring. Subsequently, 92.5 g of propionyl chloride was added to the above mixture in 4 hours while maintaining the temperature of the reaction medium between 0C and 5C under constant stirring. The reaction medium was stirred for another 1 hour until the acylation reaction was substantially completed. The reaction mass was subjected to aqueous workup to remove Zinc chloride and propionic acid, and the organic layer was separated and distilled to recover 64 g of unreacted 1,3-benzodioxole and 71 g of methyl enedioxybenzene propiophenone with a GC purity of > 99%. The methylenedioxybenzene propiophenone was charged into a 1 liter autoclave along with 125 g of isopropyl alcohol, 4 g of Raney Nickel catalyst and 0.1 g of anhydrous sodium hydrogen sulphate. The mixture was maintained at 110C under hydrogen at 100 psi pressure till unreacted methylenedioxybenzene propiophenone was reduced to less than 0.5% by GC analysis. The catalyst was separated, and the crude was distilled to give 61 g of dihydrosafrole with a yield of 105.2% (wt./wt. on 1,3-benzodioxole consumed) and purity of > 99% by GC analysis.
  • 4
  • [ 1670-14-0 ]
  • [ 20632-12-6 ]
  • 4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-phenylpyrimidine [ No CAS ]
  • 5
  • [ 71-23-8 ]
  • [ 20632-12-6 ]
  • 6-(1-propoxypropyl)-2,3-dihydro-1,4-benzodioxine [ No CAS ]
YieldReaction ConditionsOperation in experiment
100% General procedure: Carbonyl substrate, 0.02 mol, was added in portions to a suspension of 0.01 mol NaBH4 in 0.3 mol of the corresponding alcohol solvent, and the mixture was stirred for 2-2.5 h at 20C. The resulting boron derivatives of benzyl alcohols were decomposed with 10% aqueous HCl (3.7 mL), and the mixture was stirred for a required time at a required temperature(see Tables 1-5), cooled, and poured into 200 mL of cold water. The products were extracted with diethylether (2 × 40 mL), the combined extracts were washed with water and dried over anhydrous sodium sulfate, the solvent was distilled off on a rotary evaporator, and the residue was analyzed by 1H NMR. If necessary,benzyl ethers were isolated by chromatography. Alcohol coreactants poorly soluble in water were removed from the diethyl ether extracts by vacuum distillation, and the target ethers ware isolated from the still residue. Ethers 2a [9], 2c [3], 2h, 4a [10], 4b [11], 4i,4l, 7e, 10c, 10d, 10e [4], and 13a [12] were described previously. Ethers 2b, 2d-2g, 2i, 4c-4h, 4j, 4k, 4m-4w, 7a-7d, 7f, 7g, and 13b-13f are mobile liquids, and 7h-7j, 10a, 10b, and 10f-10i are viscous liquids.
  • 6
  • [ 78-83-1 ]
  • [ 20632-12-6 ]
  • 6-[1-(2-methylpropan-1-yloxy)propyl]-2,3-dihydro-1,4-benzodioxine [ No CAS ]
YieldReaction ConditionsOperation in experiment
100% General procedure: Carbonyl substrate, 0.02 mol, was added in portions to a suspension of 0.01 mol NaBH4 in 0.3 mol of the corresponding alcohol solvent, and the mixture was stirred for 2-2.5 h at 20C. The resulting boron derivatives of benzyl alcohols were decomposed with 10% aqueous HCl (3.7 mL), and the mixture was stirred for a required time at a required temperature(see Tables 1-5), cooled, and poured into 200 mL of cold water. The products were extracted with diethylether (2 × 40 mL), the combined extracts were washed with water and dried over anhydrous sodium sulfate, the solvent was distilled off on a rotary evaporator, and the residue was analyzed by 1H NMR. If necessary,benzyl ethers were isolated by chromatography. Alcohol coreactants poorly soluble in water were removed from the diethyl ether extracts by vacuum distillation, and the target ethers ware isolated from the still residue. Ethers 2a [9], 2c [3], 2h, 4a [10], 4b [11], 4i,4l, 7e, 10c, 10d, 10e [4], and 13a [12] were described previously. Ethers 2b, 2d-2g, 2i, 4c-4h, 4j, 4k, 4m-4w, 7a-7d, 7f, 7g, and 13b-13f are mobile liquids, and 7h-7j, 10a, 10b, and 10f-10i are viscous liquids.
  • 7
  • [ 20632-12-6 ]
  • [ 20625-47-2 ]
  • 8
  • [ 20632-12-6 ]
  • 6-[1-(pentyloxy)propyl]-2,3-dihydro-1,4-benzodioxine [ No CAS ]
  • 9
  • [ 20632-12-6 ]
  • 1-ethoxy-1-(3,4-ethylenedioxyphenyl)propane [ No CAS ]
  • 10
  • [ 20632-12-6 ]
  • 6-(1-methoxypropyl)-2,3-dihydro-1,4-benzodioxine [ No CAS ]
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