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Chemical Structure| 20877-88-7 Chemical Structure| 20877-88-7

Structure of 20877-88-7

Chemical Structure| 20877-88-7

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Product Details of [ 20877-88-7 ]

CAS No. :20877-88-7
Formula : C8H12N2
M.W : 136.19
SMILES Code : CNC1=CC=CC=C1CN
MDL No. :MFCD12828420

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Application In Synthesis of [ 20877-88-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 20877-88-7 ]

[ 20877-88-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17583-40-3 ]
  • [ 20877-88-7 ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; REFERENCE EXAMPLE 28 7-Ethylamino-4-(2-methyaminobenzylamino)-6-nitroquinazoline Lithium aluminum hydride (3.28 g, 86.4 mmol) was suspended in tetrahydrofuran (100 ml), followed by stirring under ice-cooling in an argon gas atmosphere. A solution of <strong>[17583-40-3]2-methylaminobenzonitrile</strong> (3.80 g, 28.8 mmol) obtained in Reference Example 1, dissolved in tetrahydrofuran (30 ml), was added dropwise and portionwise thereto. After the addition was completed, the solution was stirred for 3 hours under heating at reflux. After the reaction was completded, the reaction solution was cooled and sodium sulfate decahydrate was portionwise added thereto until foaming ceased. Thereafter, the insolubles were filtered off and the filtrate was concentrated under reduced pressure to give oily 2-methylaminobenzylamine.
 

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