Alternatived Products of [ 2091-46-5 ]
Product Details of [ 2091-46-5 ]
CAS No. : 2091-46-5
MDL No. : MFCD00011811
Formula :
C21 H18 BrP
Boiling Point :
-
Linear Structure Formula : -
InChI Key : AFZDAWIXETXKRE-UHFFFAOYSA-M
M.W :
381.25
Pubchem ID : 2724214
Synonyms :
Calculated chemistry of [ 2091-46-5 ]
Physicochemical Properties
Num. heavy atoms :
23
Num. arom. heavy atoms :
18
Fraction Csp3 :
0.05
Num. rotatable bonds :
4
Num. H-bond acceptors :
0.0
Num. H-bond donors :
0.0
Molar Refractivity :
107.72
TPSA :
13.59 Ų
Pharmacokinetics
GI absorption :
Low
BBB permeant :
No
P-gp substrate :
No
CYP1A2 inhibitor :
No
CYP2C19 inhibitor :
No
CYP2C9 inhibitor :
No
CYP2D6 inhibitor :
Yes
CYP3A4 inhibitor :
No
Log Kp (skin permeation) :
-5.44 cm/s
Lipophilicity
Log Po/w (iLOGP) :
-1.44
Log Po/w (XLOGP3) :
4.49
Log Po/w (WLOGP) :
0.7
Log Po/w (MLOGP) :
6.1
Log Po/w (SILICOS-IT) :
5.31
Consensus Log Po/w :
3.03
Druglikeness
Lipinski :
1.0
Ghose :
None
Veber :
0.0
Egan :
0.0
Muegge :
1.0
Bioavailability Score :
0.55
Water Solubility
Log S (ESOL) :
-5.35
Solubility :
0.00171 mg/ml ; 0.00000449 mol/l
Class :
Moderately soluble
Log S (Ali) :
-4.5
Solubility :
0.0122 mg/ml ; 0.0000319 mol/l
Class :
Moderately soluble
Log S (SILICOS-IT) :
-8.02
Solubility :
0.00000363 mg/ml ; 0.0000000095 mol/l
Class :
Poorly soluble
Medicinal Chemistry
PAINS :
0.0 alert
Brenk :
2.0 alert
Leadlikeness :
2.0
Synthetic accessibility :
4.35
Application In Synthesis of [ 2091-46-5 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Downstream synthetic route of [ 2091-46-5 ]
1
[ 106-96-7 ]
[ 603-35-0 ]
[ 2091-46-5 ]
Yield Reaction Conditions Operation in experiment
75.6%
With hydrogen bromide In 1,4-dioxane at 20℃; for 0.833333h;
With hydrogen bromide
With hydrogen bromide In 1,4-dioxane
In toluene at 110℃; for 2h;
Reference:
[1]Bagdasaryan; Pogosyan; Panosyan; Indzhikyan
[Russian Journal of General Chemistry, 2008, vol. 78, # 6, p. 1177 - 1183]
[2]Eiter,K.; Oedinger,H.
[Justus Liebigs Annalen der Chemie, 1965, vol. 682, p. 62 - 70]
Appleyard,G.D.; Stirling,C.J.M.
[Journal of the Chemical Society C: Organic, 1969, p. 1904 - 1908]
[3]Tamiaki, Hitoshi; Kouraba, Mitsuru
[Tetrahedron, 1997, vol. 53, # 31, p. 10677 - 10688]
[4]Chinthaparthi, Radha Rani; Gangireddy, Chandra Sekhar Reddy; Kandula, Madhu Kumar Reddy; Balam, Satheesh Krishna; Cirandur, Suresh Reddy
[Journal of Heterocyclic Chemistry, 2015, vol. 52, # 6, p. 1876 - 1882]
2
[ 110-89-4 ]
[ 2091-46-5 ]
[ 62460-47-3 ]
Yield Reaction Conditions Operation in experiment
93%
In acetonitrile Heating;
75%
In acetonitrile 1) reflux, 1 h, 2) r.t., 80 h;
75%
In acetonitrile 1.) reflux, 90 min, 2.) r.t., 80 h;
Reference:
[1]Barluenga,J.; Merino,I.; Palacios,F.
[Tetrahedron Letters, 1990, p. 6713]
[2]Booth, Brian L.; Lawrence, Nicholas J.; Pritchard, Robin G.; Rashid, Humayan S.
[Journal of the Chemical Society. Chemical communications, 1995, # 2, p. 287 - 290]
[3]Booth, Brian L.; Lawrence, Nicholas J.; Rashid, Humayan S.
[Journal of the Chemical Society. Perkin transactions I, 1997, # 23, p. 3509 - 3518]
3
[ 2091-46-5 ]
[ 59983-39-0 ]
[(E)-2-((S)-2-Methoxymethyl-pyrrolidin-1-ylamino)-propenyl]-triphenyl-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
85%
In chloroform Heating;
4
[ 2091-46-5 ]
[ 23102-11-6 ]
[ 107769-71-1 ]
Yield Reaction Conditions Operation in experiment
75%
In dichloromethane for 4h; Heating;
5
[ 2091-46-5 ]
[ 154634-96-5 ]
(-)-(S,S)-2-(3,5-dimethylmorpholino)-1-propenyltriphenylphosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
81%
In dichloromethane at 25℃; for 1h;
6
[ 2091-46-5 ]
[ 109-89-7 ]
[ 123095-03-4 ]
Yield Reaction Conditions Operation in experiment
92%
In acetonitrile Heating;
7
[ 123-75-1 ]
[ 2091-46-5 ]
2-pyrrolidinylpropenyl(triphenyl)phosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
96%
In acetonitrile 1) reflux, 1 h, 2) r.t., 80 h;
90%
In acetonitrile 1.) reflux, 90 min, 2.) r.t., 80 h;
82%
In acetonitrile for 2h; Heating;
Reference:
[1]Booth, Brian L.; Lawrence, Nicholas J.; Pritchard, Robin G.; Rashid, Humayan S.
[Journal of the Chemical Society. Chemical communications, 1995, # 2, p. 287 - 290]
[2]Booth, Brian L.; Lawrence, Nicholas J.; Rashid, Humayan S.
[Journal of the Chemical Society. Perkin transactions I, 1997, # 23, p. 3509 - 3518]
[3]Bitrus, Pogu; Booth, Brian L.
[Journal of Chemical Research, Miniprint, 1993, # 5, p. 1144 - 1155]
8
[ 2091-46-5 ]
[ 59983-39-0 ]
E-β-N-(S)-(-)-2-methoxymethylpyrrolidineamino prop-1-enylphosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
85%
With triethylamine In chloroform Heating;
9
[ 2627-86-3 ]
[ 2091-46-5 ]
(E)-triphenyl[2-(1-(S)-phenylethyl)aminoprop-1-enyl] phosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
76%
In acetonitrile 1.) reflux, 90 min, 2.) r.t., 80 h;
73%
In acetonitrile 1) reflux, 1 h, 2) r.t., 80 h;
Reference:
[1]Booth, Brian L.; Lawrence, Nicholas J.; Rashid, Humayan S.
[Journal of the Chemical Society. Perkin transactions I, 1997, # 23, p. 3509 - 3518]
[2]Booth, Brian L.; Lawrence, Nicholas J.; Pritchard, Robin G.; Rashid, Humayan S.
[Journal of the Chemical Society. Chemical communications, 1995, # 2, p. 287 - 290]
10
[ 2091-46-5 ]
[ 72748-99-3 ]
E-β-N-(R)-(+)-2-methoxymethylpyrrolidineamino prop-1-enylphosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
79%
With triethylamine In chloroform Heating;
11
[ 2091-46-5 ]
[ 60-34-4 ]
Z-β-methylhydrazino prop-1-enylphosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
91%
With triethylamine In chloroform Heating;
12
[ 3886-69-9 ]
[ 2091-46-5 ]
(E)-triphenyl[2-(1-(R)-phenylethyl)aminoprop-1-enyl] phosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
91%
In acetonitrile Heating;
13
[ 2091-46-5 ]
[ 106-49-0 ]
Triphenyl-((E)-2-p-tolylamino-propenyl)-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
78%
In acetonitrile Heating;
14
[ 2091-46-5 ]
[ 75-64-9 ]
((E)-2-tert-Butylamino-propenyl)-triphenyl-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
89%
In acetonitrile Heating;
15
[ 2091-46-5 ]
[ 107-11-9 ]
((E)-2-Allylamino-propenyl)-triphenyl-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
92%
In acetonitrile Heating;
16
[ 2091-46-5 ]
[ 459-73-4 ]
[(E)-2-(Ethoxycarbonylmethyl-amino)-propenyl]-triphenyl-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
81%
In acetonitrile Heating;
17
[ 2091-46-5 ]
[ 100-46-9 ]
((E)-2-Benzylamino-propenyl)-triphenyl-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
91%
In acetonitrile Heating;
18
[ 26961-27-3 ]
[ 2091-46-5 ]
[(E)-2-(2-Cyano-4,5-dimethoxy-phenylamino)-propenyl]-triphenyl-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
92%
In acetonitrile for 48h; Heating;
19
[ 2091-46-5 ]
[ 1885-29-6 ]
[(E)-2-(2-Cyano-phenylamino)-propenyl]-triphenyl-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
91%
In acetonitrile for 48h; Heating;
20
[ 41879-39-4 ]
[ 2091-46-5 ]
C27 H35 NOPSi(1+) *Br(1-)
[ No CAS ]
Yield Reaction Conditions Operation in experiment
90%
In chloroform Heating;
21
N-(p-toluenesulfonyl)-DL-alanine
[ No CAS ]
[ 2091-46-5 ]
triphenyl-{2-[2-(toluene-4-sulfonylamino)-propionyloxy]-allyl}-phosphonium; bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
62%
With triethylamine In dimethyl sulfoxide for 72h;
22
[ 2091-46-5 ]
[ 71-43-2 ]
(2,2-diphenyl-propyl)-triphenyl-phosphonium; chloride
[ No CAS ]
Yield Reaction Conditions Operation in experiment
85%
In trifluorormethanesulfonic acid
23
[ 110-91-8 ]
[ 2091-46-5 ]
4-{1-[(triphenyl-λ5 -phosphanylidene)-methyl]-vinyl}-morpholine
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Stage #1: morpholine; triphenyl(prop-2-ynyl)phosphonium bromide In dichloromethane at 20℃; for 1.5h;
Stage #2: With sodium hexamethyldisilazane In tetrahydrofuran at -60℃; for 4h;
Stage #3: With N,N,N,N,N,N-hexamethylphosphoric triamide In tetrahydrofuran at -30 - 20℃; Further stages.;
24
[ 2091-46-5 ]
[ 100-61-8 ]
methyl-phenyl-{1-[(triphenyl-λ5 -phosphanylidene)-methyl]-vinyl}-amine
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Stage #1: triphenyl(prop-2-ynyl)phosphonium bromide; N-methylaniline In dichloromethane at 20℃; for 1.5h;
Stage #2: With sodium hexamethyldisilazane In tetrahydrofuran at -60℃; for 4h;
Stage #3: With N,N,N,N,N,N-hexamethylphosphoric triamide In tetrahydrofuran at -30 - 20℃; Further stages.;
25
[ 2091-46-5 ]
[ 107-02-8 ]
1,2,3,4-hexatetraene
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Stage #1: triphenyl(prop-2-ynyl)phosphonium bromide With n-butyllithium In tetrahydrofuran at -10℃; for 0.5h;
Stage #2: acrolein In tetrahydrofuran at -40 - 0℃;
26
poly(3-azidopropyl methacrylate), atom transfer radical polymerization; monomer(s): 3-azidopropyl methacrylate; ethyl 2-bromoisobutyrate
[ No CAS ]
[ 2091-46-5 ]
polymer, atom transfer radical polymerization/Huisgen cycloaddition; monomer(s): 3-azidopropyl methacrylate; ethyl 2-bromoisobutyrate; propargyltriphenylphosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dimethylsulfoxide-d6 at 20℃;
27
[ 3588-30-5 ]
[ 2091-46-5 ]
[ 86-81-7 ]
C18 H22 O4
[ No CAS ]
C18 H22 O4
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Stage #1: 2-methoxy-1,3-butadiene; triphenyl(prop-2-ynyl)phosphonium bromide With zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
Stage #2: 3,4,5-trimethoxy-benzaldehyde With potassium <i>tert</i>-butylate In dichloromethane at 20℃; for 1h; Further stages. Title compound not separated from byproducts.;
28
[ 3588-30-5 ]
[ 2091-46-5 ]
[ 86-81-7 ]
[ 134029-62-2 ]
[ 97399-87-6 ]
[ 97399-88-7 ]
[ 134029-49-5 ]
Yield Reaction Conditions Operation in experiment
Stage #1: 2-methoxy-1,3-butadiene; triphenyl(prop-2-ynyl)phosphonium bromide With zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
Stage #2: 3,4,5-trimethoxy-benzaldehyde With potassium <i>tert</i>-butylate In dichloromethane at 20℃; for 1h;
Stage #3: With 2,3-dicyano-5,6-dichloro-p-benzoquinone In benzene at 20℃; for 1h; Further stages.;
29
[ 3588-30-5 ]
[ 434-45-7 ]
[ 2091-46-5 ]
C16 H15 F3 O
[ No CAS ]
C16 H15 F3 O
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Stage #1: 2-methoxy-1,3-butadiene; triphenyl(prop-2-ynyl)phosphonium bromide With zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
Stage #2: 2,2,2-Trifluoroacetophenone With potassium <i>tert</i>-butylate In dichloromethane at 20℃; for 1h; Further stages. Title compound not separated from byproducts.;
30
[ 3588-30-5 ]
[ 434-45-7 ]
[ 2091-46-5 ]
(E)-1-methoxy-4-(3,3,3-trifluoro-2-phenylprop-1-enyl)benzene
[ No CAS ]
(E)-1-methoxy-3-(3,3,3-trifluoro-2-phenylprop-1-en-1-yl)benzene
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Stage #1: 2-methoxy-1,3-butadiene; triphenyl(prop-2-ynyl)phosphonium bromide With zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
Stage #2: 2,2,2-Trifluoroacetophenone With potassium <i>tert</i>-butylate In dichloromethane at 20℃; for 1h;
Stage #3: With 2,3-dicyano-5,6-dichloro-p-benzoquinone In benzene at 20℃; for 1h; Further stages.;
31
[ 2091-46-5 ]
[ 513-81-5 ]
C27 H28 P(1+) *Br(1-)
[ No CAS ]
Yield Reaction Conditions Operation in experiment
With zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
With cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane]; zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
Reference:
[1]Hilt, Gerhard; Hengst, Christoph
[Journal of Organic Chemistry, 2007, vol. 72, # 19, p. 7337 - 7342]
[2]Hilt, Gerhard; Hengst, Christoph
[Synlett, 2006, # 19, p. 3247 - 3250]
32
[ 455-19-6 ]
[ 3588-30-5 ]
[ 2091-46-5 ]
C16 H15 F3 O
[ No CAS ]
C16 H15 F3 O
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Stage #1: 2-methoxy-1,3-butadiene; triphenyl(prop-2-ynyl)phosphonium bromide With zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
Stage #2: 4-Trifluoromethylbenzaldehyde With potassium <i>tert</i>-butylate In dichloromethane at 20℃; for 1h; Further stages. Title compound not separated from byproducts.;
33
[ 455-19-6 ]
[ 3588-30-5 ]
[ 2091-46-5 ]
1-[(Z)-2-(4-methoxyphenyl)ethenyl]-4-(trifluoromethyl)benzene
[ No CAS ]
(Z)-1-(3-methoxyphenyl)-2-(4-trifluoromethylphenyl)ethene
[ No CAS ]
[ 132312-99-3 ]
(E)-1-(3-methoxyphenyl)-2-(4-trifluoromethylphenyl)ethene
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Stage #1: 2-methoxy-1,3-butadiene; triphenyl(prop-2-ynyl)phosphonium bromide With zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
Stage #2: 4-Trifluoromethylbenzaldehyde With potassium <i>tert</i>-butylate In dichloromethane at 20℃; for 1h;
Stage #3: With 2,3-dicyano-5,6-dichloro-p-benzoquinone In benzene at 20℃; for 1h; Further stages. Title compound not separated from byproducts.;
34
[ 3588-30-5 ]
[ 2091-46-5 ]
C26 H26 PO(1+) *Br(1-)
[ No CAS ]
C26 H26 PO(1+) *Br(1-)
[ No CAS ]
Yield Reaction Conditions Operation in experiment
With zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h; Title compound not separated from byproducts.;
35
[ 2091-46-5 ]
C17 H17 F3
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Multi-step reaction with 2 steps
1: ZnI2 ; zinc / CoBr2 (dppe) / CH2 Cl2 / 0.5 h / 20 °C
2: potassium tert-butoxide / CH2 Cl2 / 1 h / 20 °C
36
[ 2091-46-5 ]
C16 H17 NO2
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Multi-step reaction with 2 steps
1: ZnI2 ; zinc / CoBr2 (dppe) / CH2 Cl2 / 0.5 h / 20 °C
2: potassium tert-butoxide / CH2 Cl2 / 1 h / 20 °C
37
[ 2091-46-5 ]
(E)-1,2-dimethyl-4-(4-(trifluoromethyl)styryl)benzene
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Multi-step reaction with 3 steps
1: ZnI2 ; zinc / CoBr2 (dppe) / CH2 Cl2 / 0.5 h / 20 °C
2: potassium tert-butoxide / CH2 Cl2 / 1 h / 20 °C
3: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 1 h / 20 °C
38
[ 2091-46-5 ]
(Z)-1,2-dimethyl-4-(4-(trifluoromethyl)styryl)benzene
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Multi-step reaction with 3 steps
1: ZnI2 ; zinc / CoBr2 (dppe) / CH2 Cl2 / 0.5 h / 20 °C
2: potassium tert-butoxide / CH2 Cl2 / 1 h / 20 °C
3: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 1 h / 20 °C
39
[ 2091-46-5 ]
(E)-1,2-dimethyl-4-(3-nitrostyryl)benzene
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Multi-step reaction with 3 steps
1: ZnI2 ; zinc / CoBr2 (dppe) / CH2 Cl2 / 0.5 h / 20 °C
2: potassium tert-butoxide / CH2 Cl2 / 1 h / 20 °C
3: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 1 h / 20 °C
40
[ 2091-46-5 ]
(Z)-1,2-dimethyl-4-(3-nitrostyryl)benzene
[ No CAS ]
Yield Reaction Conditions Operation in experiment
Multi-step reaction with 3 steps
1: ZnI2 ; zinc / CoBr2 (dppe) / CH2 Cl2 / 0.5 h / 20 °C
2: potassium tert-butoxide / CH2 Cl2 / 1 h / 20 °C
3: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 1 h / 20 °C
41
[ 3588-30-5 ]
[ 2091-46-5 ]
C26 H26 PO(1+) *Br(1-)
[ No CAS ]
Yield Reaction Conditions Operation in experiment
With cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane]; zinc(II) iodide; zinc In dichloromethane at 20℃; for 0.5h;
42
[ 106-96-7 ]
[ 603-35-0 ]
[ 2091-46-5 ]
[ 2236-01-3 ]
propadienyltriphenylphosphonium bromide
[ No CAS ]
Yield Reaction Conditions Operation in experiment
1: 45.5%
2: 16.6%
With hydrogen bromide In 1,4-dioxane at 100℃;
43
[ 2091-46-5 ]
[ 62-53-3 ]
[ 54774-75-3 ]
Yield Reaction Conditions Operation in experiment
96%
In acetonitrile at 20℃; for 27h; Reflux;
Reference:
[1]Location in patent: experimental part
Mazurkiewicz, Roman; Fryczkowska, Beata; Gabanski, Rafal; Grymel, Miroslawa; Libera, Justyna
[Phosphorus, Sulfur and Silicon and the Related Elements, 2008, vol. 183, # 6, p. 1365 - 1378]
44
[ 2091-46-5 ]
[ 100-46-9 ]
[ 123095-02-3 ]
Yield Reaction Conditions Operation in experiment
92%
In acetonitrile at 20℃; for 27h; Reflux;
Reference:
[1]Location in patent: experimental part
Mazurkiewicz, Roman; Fryczkowska, Beata; Gabanski, Rafal; Grymel, Miroslawa; Libera, Justyna
[Phosphorus, Sulfur and Silicon and the Related Elements, 2008, vol. 183, # 6, p. 1365 - 1378]
45
[ 2091-46-5 ]
[ 143-66-8 ]
triphenylpropargylphosphonium tetraphenylborate
[ No CAS ]
Yield Reaction Conditions Operation in experiment
97%
In methanol Inert atmosphere; Glovebox; Schlenk technique;
46
[ 2091-46-5 ]
[ 143-66-8 ]
C21 H18 P(1+) *BF4 (1-)
[ No CAS ]
Yield Reaction Conditions Operation in experiment
82%
In dichloromethane for 48h; Inert atmosphere; Schlenk technique; Glovebox;
47
[ 2091-46-5 ]
[ 143-66-8 ]
C21 H18 P(1+) *C24 H20 B(1-)
[ No CAS ]
Yield Reaction Conditions Operation in experiment
90%
In dichloromethane for 504h; Inert atmosphere; Schlenk technique; Glovebox;
48
pentafluorophenyl(tetrahydrothiophene)gold(I)
[ No CAS ]
[ 2091-46-5 ]
[Au(C6 F5 ){C(PPh3 )C=CH2 }]
[ No CAS ]
Yield Reaction Conditions Operation in experiment
85%
With caesium carbonate In dichloromethane at 20℃; for 3h;
49
Au(C6 F5 )3(tetrahydrothiophene)
[ No CAS ]
[ 2091-46-5 ]
[Ph3 PCH2 C≡CH][AuBr(C6 F5 )3 ]
[ No CAS ]
Yield Reaction Conditions Operation in experiment
97%
In dichloromethane at 20℃;
50
[ 39929-21-0 ]
[ 2091-46-5 ]
[AuBr{C(PPh3 )C=CH2 }]
[ No CAS ]
Yield Reaction Conditions Operation in experiment
63%
With caesium carbonate In dichloromethane at 20℃; for 4h;