Alternatived Products of [ 21429-06-1 ]
Product Details of [ 21429-06-1 ]
CAS No. : | 21429-06-1 |
MDL No. : | MFCD08052659 |
Formula : |
C7H10N2OS
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
170.23
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Pubchem ID : | - |
Synonyms : |
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Application In Synthesis of [ 21429-06-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 21429-06-1 ]
- 1
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[ 110-91-8 ]
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[ 3034-52-4 ]
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[ 21429-06-1 ]
Yield | Reaction Conditions | Operation in experiment |
72% |
With 1H-imidazole; sodium chloride; In water; for 6h;Reflux; Green chemistry; |
General procedure: In a 50-mL, round-bottom flask, 0.87 g (0.01 mol) of morpholine, 0.68 g(0.01 mol) of imidazole, 0.274 g (0.001 mol) of tributylbenzyl ammonium choride,and 1.69 g (0.01 mol) <strong>[3034-52-4]2-chlorobenzothiazole</strong> were added to 20mL of 5% NaCl (aqueous)solution. The reaction mixture was refluxed for 6 h. The progress of the reactionwas monitored by thin-layer chromatography (TLC). After completion of the reaction,the aqueous layer was washed with ethyl acetate (310 mL). The combinedorganic layer was dried over anhydrous Na2SO4 and concentrated at reduced pressure.Products were purified either by crystallizing or by flash chromatography. Whitecrystalline solid |
Reference:
[1]RSC Advances,2013,vol. 3,p. 18783 - 18786
[2]Organic and Biomolecular Chemistry,2011,vol. 9,p. 1324 - 1327
[3]Synthetic Communications,2014,vol. 44,p. 2645 - 2655
[4]Chemische Berichte,1969,vol. 102,p. 1570 - 1579
- 2
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[ 14294-10-1 ]
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[ 2032-35-1 ]
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[ 21429-06-1 ]
Yield | Reaction Conditions | Operation in experiment |
97% |
With toluene-4-sulfonic acid In ethanol; water at 90℃; for 24h; |
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Reference:
[1]Herder, Martin; Utecht, Manuel; Manicke, Nicole; Grubert, Lutz; Paetzel, Michael; Saalfrank, Peter; Hecht, Stefan
[Chemical Science, 2013, vol. 4, # 3, p. 1028 - 1040]