Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | ||||||
{[ item.p_purity ]} | {[ item.pr_size ]} | Inquiry |
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price) ]} |
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price) ]} | {[ item.pr_usastock ]} | in stock Inquiry - | {[ item.pr_chinastock ]} | {[ item.pr_remark ]} in stock Inquiry - | Login | Inquiry |
Please Login or Create an Account to: See VIP prices and availability
CAS No. : | 22531-06-2 | MDL No. : | MFCD11518791 |
Formula : | C12H14O | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | BMHUHOFPKFAGAR-UHFFFAOYSA-N |
M.W : | 174.24 | Pubchem ID : | 231508 |
Synonyms : |
|
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
![]() |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
84% | To a solution of carboxylic acid 41 (1.91 g, 9.93 mmol) and anhydrous DMF (7 drops) in anhydrous DCM (30 mL) cooled to 0 C was added oxalyl chloride (1.68 mL, 19.9 mmol) dropwise. The contents were stirred at 0 C for 1 hour, then at room temperature for 1.5 hours. The mixture was cooled to 0 C, and aluminium chloride (2.65 g, 19.9 mmol) was added. The reaction was returned to room temperature, stirred for 18 hours, and quenched at 0 C with 1N aqueous HC1 (7 mL). The reaction mixture was diluted with EtOAc (200 mL) and washed with brine (100 mL). The organic phase was dried over anhydrous Na2S04 and concentrated under reduced pressure. Purification by flash column chromatography (hexanes to 90: 10 hexanes/EtOAc) afforded 42 as a pale yellow oil (1.45 g, 84% yield). Rf = 0.40 (hexanes/EtOAc 90: 10 v/v). 1H NMR (400 MHz, CDCl3) delta 7.88 (s, 1H), 7.32 (d , J= 9.1 Hz, 1H), 7.17 (d, J= 7.8 Hz, 1H), 2.93 (t, J= 6.1 Hz, 2H), 2.71-2.62 (m, 4H), 2.12 (app quint, J= 6.4 Hz, 2H), 1.24 (t, J= 7.6 Hz, 3H). 13C NMR (101 MHz, CDCl3) delta 198.8, 142.9, 142.0, 133.4, 132.6, 128.9, 126.3, 39.4, 29.5, 28.6, 23.6, 15.7. MS (ESI+) calculated for [Ci2Hi50]+ [M+H]+, 175.1; found 175.1. | |
With PPA; | STAGE C 7-ETHYLTETRALONE STR53 25 g of polyphosphoric acid are poured into a 100-cm3 ground-necked round-bottomed flask. 2.5 g of 4-(4-ethylphenyl)butyric acid are added. The reaction mixture is stirred for 6 h at a temperature of 45 C. It is poured into ice. The resulting mixture is extracted with 3 volumes of ether. The organic phases are washed 3 times with 10% potassium carbonate solution, dried over magnesium sulfate and then evaporated to dryness. The oil obtained is purified by column chromatography. Infrared spectroscopic analysis: 3010 cm-1: nu aromatic CH 2980-2860 cm-1: nu alkyl CH 1680 cm-1: nu ketone CO 1605 cm-1: nu aromatic C=C |
[ 51015-29-3 ]
6-Methyl-3,4-dihydronaphthalen-1(2H)-one
Similarity: 1.00
[ 529-34-0 ]
3,4-Dihydronaphthalen-1(2H)-one
Similarity: 1.00
[ 22009-37-6 ]
7-Methyl-3,4-dihydronaphthalen-1(2H)-one
Similarity: 1.00
[ 13577-40-7 ]
1-(5,6,7,8-Tetrahydronaphthalen-1-yl)ethanone
Similarity: 1.00
[ 2142-76-9 ]
1-(2,6-Dimethylphenyl)ethanone
Similarity: 0.97
[ 51015-29-3 ]
6-Methyl-3,4-dihydronaphthalen-1(2H)-one
Similarity: 1.00
[ 529-34-0 ]
3,4-Dihydronaphthalen-1(2H)-one
Similarity: 1.00
[ 22009-37-6 ]
7-Methyl-3,4-dihydronaphthalen-1(2H)-one
Similarity: 1.00
[ 13577-40-7 ]
1-(5,6,7,8-Tetrahydronaphthalen-1-yl)ethanone
Similarity: 1.00
[ 2142-76-9 ]
1-(2,6-Dimethylphenyl)ethanone
Similarity: 0.97