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Chemical Structure| 23378-88-3 Chemical Structure| 23378-88-3

Structure of 23378-88-3

Chemical Structure| 23378-88-3

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Product Details of [ 23378-88-3 ]

CAS No. :23378-88-3
Formula : C6H3Cl3O3S
M.W : 261.51
SMILES Code : O=S(C1=CC(Cl)=CC(Cl)=C1O)(Cl)=O
MDL No. :MFCD00007432

Safety of [ 23378-88-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 23378-88-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 23378-88-3 ]

[ 23378-88-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 369-26-6 ]
  • [ 23378-88-3 ]
  • methyl 3-((3,5-dichloro-2-hydroxyphenyl)sulfonamido)-4-fluorobenzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
67.7% With pyridine; at 20℃; for 6h; Into a 50-mL round-bottom flask, was placed 3,5- dichloro-2-hydroxybenzene-1-sulfonyl chloride (500 mg, 1.91 mmol, 1 equiv), methyl 3-amino- 4-fluorobenzoate (388.1 mg, 2.29 mmol, 1.2 equiv), pyridine (5 mL). The resulting solution was stirred for 6 h at room temperature. The resulting mixture was washed with 1 M HC1. The resulting solution was extracted with ethyl acetate (2 x 10 mL).The organic layers were combined and concentrated under vacuum. The residue was applied onto a TLC with dichloromethane/methanol (20:1). This resulted in 510 mg (67.7%) of 61.1 as a brown solid. (ES, m/z): [M-H] 391.9.
 

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