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Chemical Structure| 234107-52-9 Chemical Structure| 234107-52-9

Structure of 234107-52-9

Chemical Structure| 234107-52-9

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Product Details of [ 234107-52-9 ]

CAS No. :234107-52-9
Formula : C9H5ClOS
M.W : 196.65
SMILES Code : O=CC1SC2C(=CC=C(C=2)Cl)C=1
MDL No. :MFCD20483652

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Application In Synthesis of [ 234107-52-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 234107-52-9 ]

[ 234107-52-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 66490-20-8 ]
  • [ 234107-52-9 ]
YieldReaction ConditionsOperation in experiment
With n-butyllithium; N,N-dimethyl-formamide; In tetrahydrofuran; at -78 - 20℃; A. 6-Chlorobenzo[b]thiophene-2-carboxaldehyde. To a solution of <strong>[66490-20-8]6-chlorobenzo[b]thiophene</strong> (1.0 g, 5.93 mmol) in THF (60 ML) at -78 C. is added a 1.6 M solution of n-BuLi in THF (3.9 ML, 6.23 mmol).After 10 minutes, 0.5 ML of DMF is added.The solution is stirred for 0.5 hours, then allowed to warm to ambient temperature.The solution is poured into a solution of saturated NH4Cl. The solution is diluted with ether and the layers are separated.The organic layer is washed with H2O and saturated NaCl. The organic layer is dried over MgSO4, filtered and concentrated.The title compound is obtained as a white solid. MS (EI): m/z 196 (M+).
 

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