Home Cart 0 Sign in  

[ CAS No. 2343-22-8 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 2343-22-8
Chemical Structure| 2343-22-8
Structure of 2343-22-8 *Storage: {[proInfo.prStorage]}

Quality Control of [ 2343-22-8 ]

Related Doc. of [ 2343-22-8 ]

SDS
Alternatived Products of [ 2343-22-8 ]
Alternatived Products of [ 2343-22-8 ]

Product Details of [ 2343-22-8 ]

CAS No. :2343-22-8MDL No. :MFCD00214461
Formula : C8H8FN Boiling Point : 224.1°C at 760 mmHg
Linear Structure Formula :-InChI Key :N/A
M.W :137.15Pubchem ID :-
Synonyms :

Computed Properties of [ 2343-22-8 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 2343-22-8 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 2343-22-8 ]

  • Upstream synthesis route of [ 2343-22-8 ]
  • Downstream synthetic route of [ 2343-22-8 ]

[ 2343-22-8 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 2343-22-8 ]
  • [ 443-69-6 ]
YieldReaction ConditionsOperation in experiment
87% With iodine pentoxide In dimethyl sulfoxide at 80℃; General procedure: Indoles 1 (0.5 mmol), DMSO (3mL) and I2O5 (1 mmol) were added into a flask and vigorously stirred at 80oC under air. The reaction was stopped until indoles were completely consumed as monitored by TLC analysis. After the completion of reaction, saturated Na2S2O3 solution (20 mL) was added to the mixture. The mixture was extracted with EtOAc (3×20 mL) and the organic layer was dried over anhydrous sodium sulfate, filtered and concentrated on a rotary evaporator. Then, the crude product was purified by column chromatography on silica gel using ethyl acetate and petroleum ether as the eluent to give the products 2.
Reference: [1] Tetrahedron Letters, 2017, vol. 58, # 18, p. 1747 - 1750
[2] Catalysis Letters, 2017, vol. 147, # 6, p. 1434 - 1440
Historical Records

Related Functional Groups of
[ 2343-22-8 ]

Fluorinated Building Blocks

Chemical Structure| 1013398-57-6

[ 1013398-57-6 ]

5-Fluoroindoline hydrochloride

Similarity: 0.98

Chemical Structure| 388078-34-0

[ 388078-34-0 ]

5-Fluoro-1-methylindoline

Similarity: 0.96

Chemical Structure| 2343-23-9

[ 2343-23-9 ]

6-Fluoroindoline

Similarity: 0.96

Chemical Structure| 954255-04-0

[ 954255-04-0 ]

5,6-Difluoroindoline

Similarity: 0.94

Chemical Structure| 1803567-63-6

[ 1803567-63-6 ]

6-Fluoroindoline hydrochloride

Similarity: 0.93

Related Parent Nucleus of
[ 2343-22-8 ]

Indolines

Chemical Structure| 1013398-57-6

[ 1013398-57-6 ]

5-Fluoroindoline hydrochloride

Similarity: 0.98

Chemical Structure| 388078-34-0

[ 388078-34-0 ]

5-Fluoro-1-methylindoline

Similarity: 0.96

Chemical Structure| 2343-23-9

[ 2343-23-9 ]

6-Fluoroindoline

Similarity: 0.96

Chemical Structure| 954255-04-0

[ 954255-04-0 ]

5,6-Difluoroindoline

Similarity: 0.94

Chemical Structure| 1803567-63-6

[ 1803567-63-6 ]

6-Fluoroindoline hydrochloride

Similarity: 0.93