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Chemical Structure| 251938-49-5 Chemical Structure| 251938-49-5

Structure of 251938-49-5

Chemical Structure| 251938-49-5

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Product Details of [ 251938-49-5 ]

CAS No. :251938-49-5
Formula : C9H16N2O3
M.W : 200.24
SMILES Code : O=C(OC(C)(C)C)N[C@H]1C(NCC1)=O
MDL No. :MFCD11616145
InChI Key :DVWCHAUBYVZILO-ZCFIWIBFSA-N
Pubchem ID :10774403

Safety of [ 251938-49-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 251938-49-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 251938-49-5 ]

[ 251938-49-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 121010-86-4 ]
  • [ 24424-99-5 ]
  • [ 251938-49-5 ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In methanol; at 20℃;Reflux; To a solution of (R) -aminopyrrolidin-2-one (1.7 g) and triethylamine (4.73 mL) in methanol (20 mL) was added di-tert- butyl bicarbonate (5.91 mL) . The reaction mixture was stirred at room temperature overnight and further heated under reflux for 2 hr. The reaction mixture was concentrated, and the residue was purified by silica gel column chromatography(ethyl acetate) .XH NMR (300 MHz, DMSO-d6) delta 1.38 (9H, s) , 1.70-1.93 (1H, m) , 2.11-2.35 (1H, m) , 3.12 (2H, dd, J = 9.3, 5.0 Hz), 3.88-4.11 (1H, m) , 7.00 (1H, d, J = 8.7 Hz), 7.69 (1H, s)
 

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