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Chemical Structure| 25333-24-8 Chemical Structure| 25333-24-8

Structure of 25333-24-8

Chemical Structure| 25333-24-8

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Product Details of [ 25333-24-8 ]

CAS No. :25333-24-8
Formula : C11H12O3
M.W : 192.21
SMILES Code : O=C(OC)CCC(C1=CC=CC=C1)=O
MDL No. :MFCD00014906
InChI Key :XVRCVKWYKYJEIG-UHFFFAOYSA-N
Pubchem ID :141190

Safety of [ 25333-24-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 25333-24-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 25333-24-8 ]

[ 25333-24-8 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 42019-78-3 ]
  • [ 25333-24-8 ]
  • (E)-methyl 5-(4-chlorophenyl)-5-(4-hydroxyphenyl)-4-phenylpent-4-enoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
73% With titanium tetrachloride; zinc; In tetrahydrofuran; at 0 - 60℃; for 3h; General procedure: To a solution of zinc (8 eq.) in THF was added TiCl4 (4 eq.) was added at 0 °C. The resulting reaction mixture was refluxed at 60 °C for 2 h. A solution of 7aed (1 eq.) and methyl 3-benzoylpropionate (1.5 eq.) were added. The resulting mixturewas refluxed at 50 °C for 1 h. The mixture was poured onto a mixture of 10percent K2CO3 solution and EtOAc. The resulting black suspension was stirred for 30 min and filtered through a short pad of Celite®. The combined aqueous layers and extracted with EtOAc. The combined organic layers was washed with brine, dried over Na2SO4, filtered and concentrated under reduced pressure. This crude compound was purified by column chromatography.
 

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Technical Information

• Acyl Group Substitution • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Benzylic Oxidation • Birch Reduction • Blanc Chloromethylation • Bouveault-Blanc Reduction • Bucherer-Bergs Reaction • Catalytic Hydrogenation • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Ester Cleavage • Fischer Indole Synthesis • Friedel-Crafts Reaction • Grignard Reaction • Henry Nitroaldol Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Hydrogenolysis of Benzyl Ether • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Alkylbenzene • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions with Organometallic Reagents • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Carbodiimides and Related Reagents • Specialized Acylation Reagents-Ketenes • Stobbe Condensation • Tebbe Olefination • Ugi Reaction • Vilsmeier-Haack Reaction • Wittig Reaction • Wolff-Kishner Reduction

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