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Chemical Structure| 25560-00-3 Chemical Structure| 25560-00-3

Structure of 25560-00-3

Chemical Structure| 25560-00-3

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Product Details of [ 25560-00-3 ]

CAS No. :25560-00-3
Formula : C9H20N2
M.W : 156.27
SMILES Code : NCCCN1C(C)CCCC1
MDL No. :MFCD00006517
InChI Key :YYAYTNPNFKPFNG-UHFFFAOYSA-N
Pubchem ID :520211

Safety of [ 25560-00-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:3267
Packing Group:

Application In Synthesis of [ 25560-00-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 25560-00-3 ]

[ 25560-00-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 25560-00-3 ]
  • [ 207399-07-3 ]
  • [ 1501-26-4 ]
  • [ 1313374-54-7 ]
YieldReaction ConditionsOperation in experiment
1 (300 mg, 0.45 mmol, 1 equiv) and l-(3-aminopropyl)-2-pipecoline (170 mg, 0.9 mmol, 2 equiv) were dissolved in ACN (2 mL), and DIEA (87 iL, 0.67 mmol, 1.5 equiv) was added. The reaction mixture was heated at 80 C for 40 minutes, and the resulting blue mixture was neutralized with 0.1 N HCl and concentrated under vacuum. The blue mixture was dissolved in DCM under N2 atmosphere, and treated with excess DIEA (700 iL, 5.39 mmol, 12 equiv) and methyl 4- (chloroformyl)butyrate (110 μ, 0.67 mmol, 1.5 equiv) at 0 C for 15 minutes. The resulting green product 2 was washed with 0.1 N HCl and brine, concentrated under vacuum, and used without further purification.
 

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