Home Cart Sign in  
Chemical Structure| 259269-58-4 Chemical Structure| 259269-58-4

Structure of 259269-58-4

Chemical Structure| 259269-58-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 259269-58-4 ]

CAS No. :259269-58-4
Formula : C11H8F3NO
M.W : 227.19
SMILES Code : FC(F)(F)OC1=CC=C(N2C=CC=C2)C=C1
MDL No. :MFCD00662480

Safety of [ 259269-58-4 ]

Application In Synthesis of [ 259269-58-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 259269-58-4 ]

[ 259269-58-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 109-97-7 ]
  • [ 103962-05-6 ]
  • [ 259269-58-4 ]
YieldReaction ConditionsOperation in experiment
95% With copper(II) acetate monohydrate; caesium carbonate; In N,N-dimethyl-formamide; at 20 - 110℃; for 24h;Inert atmosphere; Schlenk technique; General procedure: An oven-dried Schlenk tube was charged with Cu(OAc)2·H2O (0.1 mmol, 0.01 equiv), Cs2CO3(20 mmol, 2 equiv), and aryl iodide (if solid, 12 mmol, 1.2 equiv). The tube was degassed with argon for three times. Then DMF (20 mL), pyrrole (10 mmol, 1 equiv), and aryl iodide (if liquid,12 mmol, 1.2 equiv) were added via syringe under room temperature. The mixture was stirred at110 C for 24 h, and then cooled down to room temperature. The reaction mixture was quenched with water (40 mL) and extracted with ethyl ether (20 mL) for three times. The combined organic layers were dried with Na2SO4, filtered and concentrated. The crude products were purified using flash column chromatography on silica gel to afford the desired product.
 

Historical Records